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Association between birthweight and later body mass index: an individual-based pooled analysis of 27 twin cohorts participating in the CODATwins project
(Oxford University Press, 2017-10)
Background: There is evidence that birthweight is positively associated with body mass
index (BMI) in later life, but it remains unclear whether this is explained by genetic factors
or the intrauterine environment. We ...
Educational attainment of same-sex and opposite-sex dizygotic twins: An individual-level pooled study of 19 twin cohorts
(Elsevier, 2021-11)
Comparing twins from same- and opposite-sex pairs can provide information on potential sex differences in a
variety of outcomes, including socioeconomic-related outcomes such as educational attainment. It has been
suggested ...
Systematic review of the potential of MicroRNAs in the management of patients with follicular lymphoma
(Elsevier, 2021-03)
Follicular lymphoma (FL) is the second most common non-Hodgkin lymphoma and usually presents as an indolent disease. However, some patients present poor outcomes, and FL can transform into more aggressive lymphomas, such ...
Two-Sample Mendelian Randomization detects bidirectional causality between gut microbiota and celiac disease in individuals with high genetic risk
(Frontiers Media, 2023-06)
Background: Celiac Disease (CeD) is an autoimmune disorder triggered by gluten intake in genetically susceptible individuals. Highest risk individuals are homozygous for the Human Leucocyte Antigen (HLA) DQ2.5 haplotype ...
High frequency of mitochondrial haplogroups H and H2 in medieval individuals from the Cathedral of Santa María (Basque Country). Their contribution to the study of inflammatory arthropathies
(Elsevier, 2023-02)
The haplogroup H has been associated with high mitochondrial energy efficiency, which may have favoured survival and reproduction under adverse environmental conditions. On the other hand, it enhances the production of ...
The sheep miRNAome: Characterization and distribution of miRNAs in 21 tissues
(Elsevier, 2023-01)
MicroRNAs (miRNAs) are evolutionarily conserved small non-coding RNAs that regulate gene expression. In livestock species, miRNAs also show great potential as biomarkers for animal health and product quality. In sheep, few ...
Mitochondrial dysfunction promotes microbial composition that negatively impacts on ulcerative colitis development and progression
(Nature, 2023)
Recent evidence demonstrates potential links between mitochondrial dysfunction and inflammatory bowel diseases (IBD). In addition, bidirectional interactions between the intestinal microbiota and host mitochondria may ...
Association between serum fatty acids and lipoprotein subclass profile in healthy young adults: exploring common genetic and environmental factors
(Elsevier, 2014-01-21)
Objective
Little is known about the associations of serum fatty acids with lipoprotein profile and the underlying genetic and environmental etiology of these relationships. We aimed to analyze the phenotypic association ...
Genetic and environmental factors affecting birth size variation: a pooled individual-based analysis of secular trends and global geographical differences using 26 twin cohorts
(Oxford University Press, 2018-05-19)
Background: The genetic architecture of birth size may differ geographically and over
time. We examined differences in the genetic and environmental contributions to birthweight,
length and ponderal index (PI) across ...
Genetic and environmental influences on adult human height across birth cohorts from 1886 to 1994
(eLife Sciences Publications, 2016-12-14)
Human height variation is determined by genetic and environmental factors, but it
remains unclear whether their influences differ across birth-year cohorts. We conducted an
individual-based pooled analysis of 40 twin ...