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Magnetic Cross-Linked Enzyme Aggregates (mCLEAs) of Candida antarctica Lipase: An Efficient and Stable Biocatalyst for Biodiesel Synthesis
(Public Library Science, 2014-12-31)
Enzyme-catalyzed production of biodiesel is the object of extensive research due to the global shortage of fossil fuels and increased environmental concerns. Herein we report the preparation and main characteristics of a ...
Detection of Atomic Scale Changes in the Free Volume Void Size of Three-Dimensional Colorectal Cancer Cell Culture Using Positron Annihilation Lifetime Spectroscopy
Axpe Iza, Eneko; López Euba, Tamara; Castellanos Rubio, Ainara; Mérida Sanz, David; ; Plaza-Izurieta, Leticia; Fernández-Jiménez, Nora; Plazaola Muguruza, Fernando 
; Bilbao Catalá, José Ramón (Public Library of Science, 2014-01-02)
; Bilbao Catalá, José Ramón (Public Library of Science, 2014-01-02)
Positron annihilation lifetime spectroscopy (PALS) provides a direct measurement of the free volume void sizes in polymers and biological systems. This free volume is critical in explaining and understanding physical and ...
Early Functional Deficit and Microglial Disturbances in a Mouse Model of Amyotrophic Lateral Sclerosis
(Public Library of Science, 2012-04-25)
Background: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by selective motoneurons degeneration. There is today no clear-cut pathogenesis sequence nor any treatment. However growing ...
Biotic vs. Abiotic Control of Decomposition: A Comparison of the Effects of Simulated Extinctions and Changes in Temperature
Boyero González, María Luz ; Cardinale, Bradley J.; Bastian, Mikis; Pearson, Richard G. (Public Library of Science, 2014-01)
; Cardinale, Bradley J.; Bastian, Mikis; Pearson, Richard G. (Public Library of Science, 2014-01)
The loss of species is known to have significant effects on ecosystem functioning, but only recently has it been recognized that species loss might rival the effects of other forms of environmental change on ecosystem ...
Autophagic Marker MAP1LC3B Expression Levels Are Associated with Carotid Atherosclerosis Symptomatology
(Public Library Science, 2014-12-12)
Objectives: The mechanism by which atheroma plaque becomes unstable is not completely understood to date but analysis of differentially expressed genes in stable versus unstable plaques may provide clues. This will be ...
Temperature-and pH-Sensitive Nanohydrogels of Poly(N-Isopropylacrylamide) for Food Packaging Applications: Modelling the Swelling-Collapse Behaviour
(Public Library Science, 2014-02-10)
Temperature-sensitive poly(N-isopropylacrylamide) (PNIPA) nanohydrogels were synthesized by nanoemulsion polymerization in water-in-oil systems. Several cross-linking degrees and the incorporation of acrylic acid as comonomer ...
Human Endogenous Retrovirus HERV-Fc1 Association with Multiple Sclerosis Susceptibility: A Meta-Analysis
(Public Library Science, 2014-03-03)
Background: Human endogenous retroviruses (HERVs) are repetitive sequences derived from ancestral germ-line infections by exogenous retroviruses and different HERV families have been integrated in the genome. HERV-Fc1 in ...
α2,3-Sialyltransferase ST3Gal III Modulates Pancreatic Cancer Cell Motility and Adhesion In Vitro and Enhances Its Metastatic Potential In Vivo
Pérez-Garay, Marta; Arteta Ruiz, Beatriz ; Pagès, Lluís; De Llorens, Rafael; De Bolòs, Carme; Vidal Vanaclocha, Fernando; Peracaula, Rosa (Public Library of Science, 2010-09-01)
; Pagès, Lluís; De Llorens, Rafael; De Bolòs, Carme; Vidal Vanaclocha, Fernando; Peracaula, Rosa (Public Library of Science, 2010-09-01)
Background: Cell surface sialylation is emerging as an important feature of cancer cell metastasis. Sialyltransferase expression has been reported to be altered in tumours and may account for the formation of sialylated ...
Optimal Resting-Growth Strategies of Microbial Populations in Fluctuating Environments
(Public Library of Science, 2011-04-15)
Bacteria spend most of their lifetime in non-growing states which allow them to survive extended periods of stress and starvation. When environments improve, they must quickly resume growth to maximize their share of limited ...
High-Throughput Sequencing of microRNAs in Peripheral Blood Mononuclear Cells: Identification of Potential Weight Loss Biomarkers
Milagro Yoldi, Fermín I.; Miranda Gómez, Jonatan ; Portillo Baquedano, María Puy ; Fernández Quintela, Alfredo ; Campión Zabalza, Javier; Martínez, José Alfredo (Public Library of Science (PLoS), 2013)
; Portillo Baquedano, María Puy ; Fernández Quintela, Alfredo ; Campión Zabalza, Javier; Martínez, José Alfredo (Public Library of Science (PLoS), 2013)
INTRODUCTION: MicroRNAs (miRNAs) are being increasingly studied in relation to energy metabolism and body composition homeostasis. Indeed, the quantitative analysis of miRNAs expression in different adiposity conditions ...