Browsing Artículos by Author "OCHOA DE RETANA MENDIBIL, ANA MARIA"
Now showing items 1-5 of 5
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BSA- and Elastin-Coated GO, but Not Collagen-Coated GO, Enhance the Biological Performance of Alginate Hydrogels
Raslan, Ahmed; Sáenz del Burgo Martínez, Laura ; Espona Noguera, Albert; Ochoa de Retana Mendibil, Ana María ; Sanjuán, María Luisa; Cañibano Hernández, Alberto; Gálvez Martín, Patricia; Ciriza Astrain, Jesús; Pedraz Muñoz, José Luis (MDPI, 2020-06-11)The use of embedded cells within alginate matrices is a developing technique with great clinical applications in cell-based therapies. However, one feature that needs additional investigation is the improvement of ... -
Design and Evaluation of New Phosphorus Substituted Aziridines as Antiproliferative Agents
De los Santos Ruiz, Jesús Manuel ; Carramiñana Jiménez, Víctor; Ochoa de Retana Mendibil, Ana María ; Vélez del Burgo Pérez, Ander; Palacios Gambra, Francisco Javier (MDPI, 2019-08-09)Covalent bond formation has become a safe and effective strategy applied not only by nature but also by the pharmaceutical industry to improve disease pharmacology. In the history of modern medicine, covalent drugs have ... -
Diastereoselective ZnCl2-Mediated Joullié–Ugi Three-Component Reaction for the Preparation of Phosphorylated N-Acylaziridines from 2H-Azirines
Allende, Julene; Olaizola Alvarez, Yurre; Ochoa de Retana Mendibil, Ana María ; Palacios, Francisco; De los Santos Ruiz, Jesús Manuel (MDPI, 2024-02-27)We disclose a direct approach to the diastereoselective synthesis of phosphorus substituted N-acylaziridines based on a one-pot ZnCl2-catalyzed Joullié–Ugi three-component reaction of phosphorylated 2H-azirines, carboxylic ... -
Modulation of Conductivity of Alginate Hydrogels Containing Reduced Graphene Oxide through the Addition of Proteins
Raslan, Ahmed; Ciriza Astrain, Jesús; Ochoa de Retana Mendibil, Ana María ; Sanjuán, María Luisa; Toprak, Muhammet S.; Gálvez Martín, Patricia; Sáenz del Burgo Martínez, Laura ; Pedraz Muñoz, José Luis (MDPI, 2021-09-15)Modifying hydrogels in order to enhance their conductivity is an exciting field with applications in cardio and neuro-regenerative medicine. Therefore, we have designed hybrid alginate hydrogels containing uncoated and ... -
Synthesis and Antiproliferative Activity of Phosphorus Substituted 4-Cyanooxazolines, 2-Aminocyanooxazolines, 2-Iminocyanooxazolidines and 2-Aminocyanothiazolines by Rearrangement of Cyanoaziridines
Carramiñana Jiménez, Víctor; Ochoa de Retana Mendibil, Ana María ; Palacios Gambra, Francisco Javier ; De los Santos Ruiz, Jesús Manuel (MDPI, 2021-07-14)Several phosphorus-substituted N-acylated cyanoaziridines 2 and N-carbamoylated cyanoziridines 5 were prepared in good to high yields. N-Acylated cyanoaziridines 2 were used, after ring expansion, in an efficient synthesis ...