Browsing Artículos by Author "Horrillo, Igor"
Now showing items 1-5 of 5
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Cannabis use selectively modulates circulating biomarkers in the blood of schizophrenia patients
Ibarra Lecue, Inés ; Unzueta Larrinaga, Paula; Barrena Barbadillo, Rocío; Villate Uribe, Aitor; Horrillo Furundarena, Igor ; Mendivil, Begoña; Landabaso, Miguel A.; Meana Martínez, José Javier ; Etxebarria Loizate, Nestor; Callado Hernando, Luis Felipe ; Urigüen Echeverría, Leyre (Wiley, 2022-11)Cannabis use disorder is frequent in schizophrenia patients, and it is associated with an earlier age of onset and poor schizophrenia prognosis. Serotonin 2A receptors (5-HT2AR) have been involved in psychosis and, like ... -
High S100B Levels Predict Antidepressant Response in Patients With Major Depression Even When Considering Inflammatory and Metabolic Markers
Navinés, Ricard; Oriolo, Giovanni; Horrillo Furundarena, Igor ; Cavero, Myriam ; Aouizerate, Bruno; Schaefer, Martin; Capuron, Lucile ; Meana Martínez, José Javier ; Martín Santos, Rocío (Oxford University, 2022-06)[EN] Background The relationship between antidepressant response and glial, inflammatory, and metabolic markers is poorly understood in depression. This study assessed the ability of biological markers to predict antidepressant ... -
Isolation and Differentiation of Neurons and Glial Cells from Olfactory Epithelium in Living Subjects
Unzueta Larrinaga, Paula; Barrena Barbadillo, Rocío; Ibarra Lecue, Inés ; Horrillo Furundarena, Igor ; Villate Uribe, Aitor; Recio Barbero, María; Meana Martínez, José Javier ; Díez Alarcia, Rebeca ; Mentxaka Solozabal, Oihane; Segarra Echevarria, Rafael; Etxebarria Loizate, Nestor; Callado Hernando, Luis Felipe ; Urigüen Echeverría, Leyre (Springer Nature, 2023)The study of psychiatric and neurological diseases requires the substrate in which the disorders occur, that is, the nervous tissue. Currently, several types of human bio-specimens are being used for research, including ... -
Pimavanserin exhibits serotonin 5-HT 2A receptor inverse agonism for G αi1 - and neutral antagonism for G αq/11 -proteins in human brain cortex
Muneta Arrate, Itziar ; Díez Alarcia, Rebeca ; Horrillo Furundarena, Igor ; Meana Martínez, José Javier (Elsevier, 2020-06-07)[EN] Pimavanserin is claimed as the first antipsychotic drug that shows selectivity for serotonin 5- HT 2 receptors (5-HT 2 Rs) and lacks of affinity for dopamine D 2 receptors (D 2 Rs). Cell-based func- tional assays ... -
Serotonin 5-HT2A, 5-HT2c and 5-HT1A receptor involvement in the acute effects of psilocybin in mice. In vitro pharmacological profile and modulation of thermoregulation and head-twich response
Erkizia Santamaría, Inés; Allés Pascual, Roser; Horrillo Furundarena, Igor ; Meana Martínez, José Javier ; Ortega Calvo, Jorge (Elsevier, 2022-10)The psychedelic 5-HT2A receptor (5HT2AR) agonist psilocybin (or the active metabolite psilocin) has emerged as potential useful drug for various neuropsychiatric diseases, with a rapid onset of therapeutic activity. However, ...