Browsing Artículos by Author "M. de Pancorbo, Marian"
Now showing items 1-20 of 24
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A novel form of human disease with a protease-sensitive prion protein and heterozygosity methionine/valine at codon 129: Case report
Rodríguez Martínez, Ana B.; Garrido Urkullu, Joseba M.; Zarranz Imirizaldu, Juan José; Arteagoitia, Jose M.; Martínez de Pancorbo Gómez, María de los Angeles; Atares, Begona; Bilbao, Miren J.; Ferrer, Isidro; Juste Jordán, Ramón A. (BioMed Central, 2010-10)
Background: Sporadic Creutzfeldt-Jakob disease (sCJD) is a rare neurodegenerative disorder in humans included in the group of Transmissible Spongiform Encephalopathies or prion diseases. The vast majority of sCJD cases are ... -
Cell Patterning Technology on Polymethyl Methacrylate through Controlled Physicochemical and Biochemical Functionalization
Azuaje Hualde, Enrique; Komen, Job; Alonso Cabrera, Juncal Anne
; Van den Berg, Albert; Martínez de Pancorbo Gómez, María de los Angeles
; Van der Meer, Andries D.; Benito López, Fernando
; Basabe Desmonts, Lourdes
(MDPI, 2023-09-23)
In recent years, innovative cell-based biosensing systems have been developed, showing impact in healthcare and life science research. Now, there is a need to design mass-production processes to enable their commercialization ... -
Continuous Monitoring of Cell Transfection Efficiency with Micropatterned Substrates
Azuaje Hualde, Enrique; Rosique, Melania; Calatayud Sánchez, Alba
; Benito López, Fernando
; Basabe Desmonts, Lourdes
; Martínez de Pancorbo Gómez, María de los Angeles
(Wiley, 2021-04-10)
The effect of cell-cell contact on gene transfection is mainly unknown. Usually, transfection is carried out in batch cell cultures without control over cellular interactions, and efficiency analysis ... -
Design and Validation of a Process Based on Cationic Niosomes for Gene Delivery into Novel Urine-Derived Mesenchymal Stem Cells
Vado Ranedo, Yerai; Puras Ochoa, Gustavo; Rosique, Melania; Martín Plágaro, César Augusto
; Pedraz Muñoz, José Luis
; Jebari Benslaiman, Shifa; Martínez de Pancorbo Gómez, María de los Angeles
; Zarate Sesma, Jon
; Pérez de Nanclares Leal, Guiomar (MDPI, 2021-05-11)
Background: Mesenchymal stem cells (MSCs) are stem cells present in adult tissues. They can be cultured, have great growth capacity, and can differentiate into several cell types. The isolation of urine-derived mesenchymal ... -
Different Evolutionary History for Basque Diaspora Populations in USA and Argentina Unveiled by Mitochondrial DNA Analysis
Baeta Bafalluy, Miriam; Núñez Domingo, Carolina; Cardoso Martín, Sergio; Palencia Madrid, Leire
; Piñeiro Hermida, Sergio; Arriba Barredo, Miren; Villanueva Millán, María Jesús; Martínez de Pancorbo Gómez, María de los Angeles
(Public Library Science, 2015-12-14)
The Basque Diaspora in Western USA and Argentina represents two populations which have maintained strong Basque cultural and social roots in a completely different geographic context. Hence, they provide an exceptional ... -
Distinct Correlations Between Lipogenic Gene Expression and Fatty Acid Composition of Subcutaneous Fat Among Cattle Breeds
Gamarra, David; Aldai Elkoro-Iribe, Noelia; Arakawa, Aisaku; Rodríguez Barrón, Luis Javier; López Oceja, Andrés; Martínez de Pancorbo Gómez, María de los Angeles
; Taniguchi, Masaaki (Biomed Central, 2018-05-23)
Background: The fatty acid (FA) composition of adipose tissue influences the nutritional quality of meat products. The unsaturation level of FAs is determined by fatty acid desaturases such as stearoyl- CoA desaturases ... -
DNA methylation epigenotypes in breast cancer molecular subtypes
García Bediaga, Naiara; Acha Sagredo, Amelia; Guerra, Isabel; Viguri, Amparo; Albaina, Carmen; Ruiz Díaz, Irune; Rezola, Ricardo; Alberdi, María Jesús; Dopazo, Joaquín; Montaner, David; Renobales Scheifler, María Mercedes de; Fernández Fernández, Agustín; Field, John K.; Fraga, Mario F.; Liloglou, Liloglou; Martínez de Pancorbo Gómez, María de los Angeles(BioMed Central, 2010-09-29)
Introduction: Identification of gene expression-based breast cancer subtypes is considered a critical means of prognostication. Genetic mutations along with epigenetic alterations contribute to gene-expression changes ... -
Extracellular matrix protein microarray-based biosensor with single cell resolution: Integrin profiling and characterization of cell-biomaterial interactions
González Pujana, Ainhoa; Santos Vizcaíno, Edorta; García Hernando, Maite
; Hernáez Estrada, Beatriz; Martínez de Pancorbo Gómez, María de los Angeles
; Benito López, Fernando
; Igartua Olaechea, Manuela
; Basabe Desmonts, Lourdes
; Hernández Martín, Rosa María
(Elsevier, 2019-08-06)
In the search of biomaterials that promote cell adhesion, it is crucial to explore the integrin-substrate dynamic interactions given in a certain cell type to design successful biofunctionalization strategies. Here, we use ... -
Food groups, diet quality and colorectal cancer risk in the Basque Country
Alegría Lertxundi, Iker; Aguirre Gómez, Carmelo; Bujanda Fernández de Pierola, Luis; Fernández Pablos, Francisco Javier; Polo, Francisco; Ordovás, José María; Etxezarraga Zuluaga, María Carmen; Zabalza Estévez, Ignacio; Larzabal, Mikel; Portillo Villares, María Isabel; Martínez de Pancorbo Gómez, María de los Angeles
; García Etxebarria, Koldo; Rocandio Pablo, Ana María
; Arroyo Izaga, Marta (Baishideng Publishing Group Inc, 2020-07-28)
BACKGROUND The results obtained to date concerning food groups, diet quality and colorectal cancer (CRC) risk vary according to criteria used and the study populations. AIM To study the relationships between food groups, ... -
Genetic Characterization of the Local Pirenaica Cattle for Parentage and Traceability Purposes
Gamarra, David; Taniguchi, Masaaki; Aldai Elkoro-Iribe, Noelia; Arakawa, Aisaku; López Oceja, Andrés; Martínez de Pancorbo Gómez, María de los Angeles(MDPI, 2020-09-05)
Pirenaica is the most important autochthonous cattle breed within the Protected Geographic Indication (PGI) beef quality label in the Basque region, in northern Spain. The short tandem repeats (STRs) are powerful markers ... -
Gene–Diet Interactions in Colorectal Cancer: Survey Design, Instruments, Participants and Descriptive Data of a Case–Control Study in the Basque Country
Alegría Lertxundi, Iker; Aguirre Gómez, Carmelo; Bujanda Fernández de Pierola, Luis; Fernández Pablos, Francisco Javier; Polo, Francisco; Ordovás, José María; Etxezarraga Zuluaga, María Carmen; Zabalza Estévez, Ignacio; Larzabal, Mikel; Portillo Villares, María Isabel; Martínez de Pancorbo Gómez, María de los Angeles
; Palencia Madrid, Leire
; García Etxebarria, Koldo; Rocandio Pablo, Ana María
; Arroyo Izaga, Marta (MDPI, 2020)
Epidemiologic studies have revealed inconsistent evidence of gene-diet interaction in relation to colorectal cancer (CRC). The aim of this study was to analyze them in a sample of cases and controls from the population-based ... -
Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project
GRACE Consortium; DEGESCO Consortium; Alzheimers Dis Neuroimaging Initia; GRACE Study Group; Martínez de Pancorbo Gómez, María de los Angeles; López de Munain Arregui, Adolfo José (Elsevier Science INC, 2019-10)
Introduction: Large variability among Alzheimer's disease (AD) cases might impact genetic discoveries and complicate dissection of underlying biological pathways. Methods: Genome Research at Fundacio ACE (GR@ACE) is a ... -
Influence of methyl donor nutrients as epigenetic regulators in colorectal cancer: A systematic review of observational studies
Chávez Hidalgo, Lourdes Pilar; Martín Fernández de Labastida, Silvia; Martínez de Pancorbo Gómez, María de los Angeles; Arroyo Izaga, Marta (Baishideng, 2023)
BACKGROUNDDietary methyl donors might influence DNA methylation during carcinogenesis of colorectal cancer (CRC). However, whether the influence of methyl donor intake is modified by polymorphisms in such epigenetic ... -
Microtechnologies for Cell Microenvironment Control and Monitoring
Azuaje Hualde, Enrique; García Hernando, Maite
; Etxebarria Elezgarai, Jaione
; Martínez de Pancorbo Gómez, María de los Angeles
; Benito López, Fernando
; Basabe Desmonts, Lourdes
(MDPI, 2017-06)
A great breadth of questions remains in cellular biology. Some questions cannot be answered using traditional analytical techniques and so demand the development of new tools for research. In the near future, the development ... -
Mitochondrial DNA Reveals the Trace of the Ancient Settlers of a Violently Devastated Late Bronze and Iron Ages Village
Núñez Domingo, Carolina; Baeta Bafalluy, Miriam; Cardoso Martín, Sergio; Palencia Madrid, Leire
; García Romero, Noemí; Llanos, Armando; Martínez de Pancorbo Gómez, María de los Angeles
(Public Library Science, 2016-05-13)
La Hoya (Alava, Basque Country) was one of the most important villages of the Late Bronze and Iron Ages of the north of the Iberian Peninsula, until it was violently devastated around the 4th century and abandoned in the ... -
Naked Eye Y Amelogenin Gene Fragment Detection Using DNAzymes on a Paper-based Device
Azuaje Hualde, Enrique; Arroyo Jiménez, Susana; Garai Ibabe, Gaizka; Benito López, Fernando
; Martínez de Pancorbo Gómez, María de los Angeles
(Elsevier, 2020-05-07)
Nowadays, there are strong efforts in developing new technology for rapid detection of specific DNA sequences for environmental monitoring, forensic analysis and rapid biomedical diagnosis applications. That is where ... -
On-campus food purchase behaviors, choice determinants, and opinions on food availability in a Spanish university community
Martínez Pérez, Naiara; Telleria Aramburu, Nerea
; Insua Cerretani, Patricia; Hernández Pintor, Idoia; Telletxea Artzamendi, Saioa
; Ansotegui Alday, Laura; Rebato Ochoa, Esther Matilde
; Basabe Barañano, María Dolores
; Martínez de Pancorbo Gómez, María de los Angeles
; Rocandio Pablo, Ana María
; Arroyo-Izaga, Marta (Elsevier, 2022-11)
Objective: The aim of this study was to investigate food purchasing behaviors, choice determinants, and opin-ions about on-campus food availability by a university community and to analyze differences in these aspects ... -
Optical Single Cell Resolution Cytotoxicity Biosensor Based onSingle Cell Adhesion Dot Arrays
García Hernando, Maite; Calatayud Sánchez, Alba
; txebarria Elezgarai, Jaione; Martínez de Pancorbo Gómez, María de los Angeles
; Benito López, Fernando
; Basabe Desmonts, Lourdes
(American Chemical Society, 2020-05-28)
Low cost easy to use cell viability tests are needed in the pharmaceutical, biomaterial and environmental industry to measure adverse cellular effects. Herein we present a new methodology to track cell death with high ... -
Paper based microfluidic platform for single-step detection of mesenchymal stromal cells secreted VEGF
Azuaje Hualde, Enrique; Martínez de Pancorbo Gómez, María de los Angeles
; Benito López, Fernando
; Basabe Desmonts, Lourdes
(Elsevier, 2022-03-22)
[EN] Low cost and user-friendly paper microfluidic devices, combined with DNA-based biosensors with binding capacities for specific molecules, have been proposed for the developing of novel platforms that ease and speed-up ... -
Single nucleotide polymorphisms associated with susceptibility for development of colorectal cancer: Case-control study in a Basque population
Alegría Lertxundi, Iker; Aguirre Gómez, Carmelo; Bujanda Fernández de Pierola, Luis; Fernández Pablos, Francisco Javier; Polo, Francisco; Ordovás, José María; Etxezarraga Zuluaga, María Carmen; Zabalza Estévez, Ignacio; Larzabal, Mikel; Portillo Villares, María Isabel; Martínez de Pancorbo Gómez, María de los Angeles
; Palencia Madrid, Leire
; Rocandio Pablo, Ana María
; Arroyo Izaga, Marta (Public Library Science, 2019-12-10)
Given the significant population diversity in genetic variation, we aimed to investigate whether single nucleotide polymorphisms (SNPs) previously identified in studies of colorectal cancer (CRC) susceptibility were also ...