Browsing Artículos by Author "Caballero Camino, Francisco Javier"

Now showing items 1-4 of 4

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      Inhibition of NAE-dependent protein hyper-NEDDylation in cystic cholangiocytes halts cystogenesis in experimental models of polycystic liver disease 

      Lee-Law, Pui Y.; Olaizola Rebe, Paula; Caballero Camino, Francisco Javier ORCID; Izquierdo Sánchez, Laura; Rodrigues, Pedro M.; Perugorria Montiel, María Jesús; Azkargorta, Mikel; Elortza, Felix; Martínez Chantar, María Luz ORCID; Aspichueta Celaá, Patricia; Bujanda Fernández de Pierola, Luis ORCID; Drenth, Joost P. H.; Bañales Asurmendi, Jesús María ORCID (Sage, 2021-09)
      Background Polycystic liver diseases (PLDs) are genetic inherited disorders characterized by the progressive growth of numerous intrahepatic biliary cysts, which are the main cause of morbidity. Previous studies revealed ...
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      Synthetic Conjugates of Ursodeoxycholic Acid Inhibit Cystogenesis in Experimental Models of Polycystic Liver Disease 

      Caballero Camino, Francisco Javier ORCID; Rivilla de la Cruz, Iván ORCID; Herráez Aguilar, Elisa; Briz Sánchez, Oscar; Santos Laso, Álvaro; Izquierdo Sánchez, Laura; Lee-Law, Pui Y.; Rodrigues, Pedro M.; Muñoz Garrido, Patricia; Jin, Sujeong; Peixoto, Estanislao; Richard, Seth; Gradilone, Sergio A.; Perugorria Montiel, María Jesús; Esteller, Manel; Bujanda Fernández de Pierola, Luis ORCID; Marin, José J. G.; Bañales Asurmendi, Jesús María ORCID; Cossío Mora, Fernando Pedro ORCID (Wiley, 2020-09-22)
      Background and Aims Polycystic liver diseases (PLDs) are genetic disorders characterized by progressive development of symptomatic biliary cysts. Current surgical and pharmacological approaches are ineffective, and liver ...
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      Targeting NAE1-mediated protein hyper-NEDDylation halts cholangiocarcinogenesis and impacts on tumor-stroma crosstalk in experimental models. 

      Olaizola Rebe, Paula; Lee-Law, Pui Y.; García Fernández de Barrena, Maite; Álvarez Asiain, Laura; Cadamuro, Massimiliano ORCID; Azkargorta, Mikel; O’Rourke, Colm J.; Caballero Camino, Francisco Javier ORCID; Olaizola, Irene; Rodríguez Macías, Rocío Isabel; García Marín, Jose Juan; Serrano Maciá, Marina; Martínez Chantar, María Luz ORCID; Ávila, Matías A. ORCID; Aspichueta Celaá, Patricia; CALVISI, Diego Francesco ORCID; Evert, Matthias; Fabris, Luca; Castro, Rui ORCID; Elortza, Felix; Andersen, Jesper B.; Bujanda Fernández de Pierola, Luis ORCID; Rodrigues, Pedro M.; Perugorria, Maria Jesus ORCID; Bañales Asurmendi, Jesús María ORCID (Elsevier, 2022-07)
      [EN] BACKGROUND & AIMS: Cholangiocarcinoma (CCA) comprises a heterogeneous group of malignant tumors associated with dismal prognosis. Alterations in post-translational modifications (PTMs), including NEDDylation, result ...
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      Targeting UBC9-Mediated Protein Hyper-SUMOylation in Cystic Cholangiocytes Halts Polycystic Liver Disease in Experimental Models 

      Lee-Law, Pui Y.; Olaizola Rebe, Paula; Caballero Camino, Francisco Javier ORCID; Izquierdo Sánchez, Laura; Rodrigues, Pedro M.; Santos Laso, Álvaro; Azkargorta, Mikel; Elortza, Felix; Martínez Chantar, María Luz ORCID; Perugorria Montiel, María Jesús; Aspichueta Celaá, Patricia; Marzioni, Marco; LaRusso, Nicholas F.; Bujanda Fernández de Pierola, Luis ORCID; Drenth, Joost P. H.; Bañales Asurmendi, Jesús María ORCID (Elsevier, 2021-02)
      BACKGROUND & AIMS: Polycystic liver diseases (PLDs) are genetic disorders characterized by progressive development of multiple fluid-filled biliary cysts. Most PLD-causative genes participate in protein biogenesis and/or ...