Browsing Artículos by Author "CRENDE ARRUABARRENA, OLATZ"
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GeromiRs Are Downregulated in the Tumor Microenvironment during Colon Cancer Colonization of the Liver in a Murine Metastasis Model
Gerovska, Daniela; García Gallastegui, Patricia ; Crende Arruabarrena, Olatz ; Márquez Clavijo, Joana ; Larrinaga Embeita, Gorka ; Unzurrunzaga, Maite; Araúzo Bravo, Marcos J.; Badiola Echaburu, Iker (MDPI, 2021-05-01)Cancer is a phenomenon broadly related to ageing in various ways such as cell cycle deregulation, metabolic defects or telomerases dysfunction as principal processes. Although the tumor cell is the main actor in cancer ... -
Is There Such a Thing as a Genuine Cancer Stem Cell Marker? Perspectives from the Gut, the Brain and the Dental Pulp
Crende Arruabarrena, Olatz ; García Gallastegui, Patricia ; Luzuriaga González, Jon ; Badiola Echaburu, Iker ; De la Hoz Torres, Carmen; Unda Rodríguez, Fernando José ; Ibarretxe Bilbao, Gaskon ; Pineda Martí, José Ramón (MDPI, 2020-11-27)The conversion of healthy stem cells into cancer stem cells (CSCs) is believed to underlie tumor relapse after surgical removal and fuel tumor growth and invasiveness. CSCs often arise from the malignant transformation of ... -
Vascular endothelial growth factor regulates melanoma cell adhesion and growth in the bone marrow microenvironment via tumor cyclooxygenase-2
Valcarcel, María; Mendoza, Lorea; Hernández, José Julio; Carrascal, Teresa; Salado, Clarisa; Crende Arruabarrena, Olatz ; Vidal Vanaclocha, Fernando (BioMed Central, 2011-08)Background: Human melanoma frequently colonizes bone marrow (BM) since its earliest stage of systemic dissemination, prior to clinical metastasis occurrence. However, how melanoma cell adhesion and proliferation mechanisms ... -
What Are the Roles of Proprotein Convertases in the Immune Escape of Tumors?
Mehranzadeh, Elham; Crende Arruabarrena, Olatz ; Badiola Echaburu, Iker ; García Gallastegui, Patricia (MDPI, 2022-12-19)Protein convertases (PCs) play a significant role in post-translational procedures by transforming inactive precursor proteins into their active forms. The role of PCs is crucial for cellular homeostasis because they are ...