BackBrowsing Artículos by Author "Ubarretxena-Belandia, Iban"
Now showing items 1-4 of 4
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Conformational Plasticity Underlies Membrane Fusion Induced by an HIV Sequence Juxtaposed to the Lipid Envelope
; Torralba Iturbe, Johana
; ; ; Ubarrechena Belandia, Iván ; ; Apellaniz Unzalu, Beatriz ; Nieva Escandón, José Luis (Springer Nature, 2021-01-14)
Envelope glycoproteins from genetically-divergent virus families comprise fusion peptides (FPs) that have been posited to insert and perturb the membranes of target cells upon activation of the virus-cell fusion reaction. ... -
Cryo-EM structure of translesion DNA synthesis polymerase ζ with a base pair mismatch
Malik, Radhika; Johnson, Robert E.; Prakash, Louise; Prakash, Satya; Ubarrechena Belandia, Iván; Aggarwal, Aneel K. (Nature Research, 2022-02)
[EN] The B-family multi-subunit DNA polymerase ζ (Polζ) is important for translesion DNA synthesis (TLS) during replication, due to its ability to extend synthesis past nucleotides opposite DNA lesions and mismatched base ... -
Design and validation of an open-source modular Microplate Photoirradiation System for high-throughput photobiology experiments
Katz, Suzanna; Backeris, Peter; Merck, Christopher; Suprun, Maria; D’Souza, Sunita; Bishop, David F.; Desnick, Robert J.; Moore, Kateri; Ubarrechena Belandia, Iván; Lemischka, Ihor R. (Public Library Science, 2018-10-05)
Research in photobiology is currently limited by a lack of devices capable of delivering precise and tunable irradiation to cells in a high-throughput format. This limits researchers to using expensive commercially available ... -
Presenilin1 familial Alzheimer disease mutants inactivate EFNB1- and BDNF-dependent neuroprotection against excitotoxicity by affecting neuroprotective complexes of N-methyl-d-aspartate receptor
Al Rahim, Md; Yoon, Yonejung; Dimovasili, Christina; Shao, Zhiping; Huang, Qian; Zhang, Emily; Kezunovic, Nebojsa; Chen, Lei; Schaffner, Adam; Huntley, George W.; Ubarrechena Belandia, Iván; Georgakopoulos, Anastasios; Robakis, Nikolaos K. (Oxfor University Press, 2020-07-20)
Excitotoxicity is thought to play key roles in brain neurodegeneration and stroke. Here we show that neuroprotection against excitotoxicity by trophic factors EFNB1 and brain-derived neurotrophic factor (called here factors) ...