BackBrowsing Artículos by Author "Cortajarena, Aitziber"
Now showing items 1-7 of 7
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3D Printed Bioplastics with Shape-Memory Behavior Based on Native Bovine Serum Albumin
; Smith, Patrick T.
; Gómez López, Álvaro ; Fernandez, Maxence ; López Cortajarena, Aitziber ; ; Nelson, Alshakim (ACS, 2022-04-19)
Bio-based plastics that can supplant petroleum-derived materials are necessary to meet the future demands of sustainability in the life cycle of plastic materials. While there are significant efforts to develop protein-based ... -
An Emerging Nanozyme Class for à la carte Enzymatic-Like Activities based on Protein-Metal Nanocluster Hybrids
; ; ; ; López Cortajarena, Aitziber (Wiley, 2023-09)
In this study, the goal is to fabricate robust and highly efficient peroxidase-like nanozymes that can ultimately be assembled into films for their easy reuse in catalytic cycles. Nanozymes are designed by mimicking the ... -
Enhancing the Photocatalytic Conversion of Pt(IV) Substrates by Flavoprotein Engineering
; Martínez Martínez, Virginia; ; ; ; ; López Cortajarena, Aitziber ; (ACS, 2021-05-07)
Our recent work demonstrates that certain flavoproteins can catalyze the redox activation of Pt(IV) prodrug complexes under light irradiation. Herein, we used site-directed mutagenesis on the mini singlet oxygen generator ... -
High-throughput virtual search of small molecules for controlling the mechanical stability of human CD4
; ; ; ; ; ; ; ; ; López Cortajarena, Aitziber; ; San Sebastián Larzabal, Eider ; (Elsevier, 2024-04)
Protein mechanical stability determines the function of a myriad of proteins, especially proteins from the extracellular matrix. Failure to maintain protein mechanical stability may result in diseases and disorders such ... -
In vitro Production of Hemin-Based Artificial Metalloenzymes
; ; ; ; López Cortajarena, Aitziber (Wiley, 2024-02)
Developing enzyme alternatives is pivotal to improving and enabling new processes in biotechnology and industry. Artificial metalloenzymes (ArMs) are combinations of protein scaffolds with metal elements, such as metal ... -
Nanozymes with versatile redox capabilities inspired in metalloenzymes
; ; ; ; ; López Cortajarena, Aitziber (RSC, 2023)
Metalloenzymes represent exemplary systems in which an organic scaffold combines with a functional inorganic entity, resulting in excellent redox catalysts. Inspired by these natural hybrid biomolecules, biomolecular ... -
Toward Supramolecular Nanozymes for the Photocatalytic Activation of Pt(IV) Anticancer Prodrugs
Mazzei, Laura Filomena; Martínez, Álvaro; Trevisan, Lucia; Rosa Gastaldo, Daniele; López Cortajarena, Aitziber; Mancin, Fabrizio; Salassa, Luca (Royal Society Of Chemistry, 2020-09-16)
A supramolecular nanozyme for the photocatalytic conversion of a Pt(IV) anticancer complex to cisplatin is described herein. We employed 1.9 nm Au nanoparticles decorated with thiol ligands bearing a TACN (1,4,7-triazacyclononane) ...