Browsing Artículos by Author "Lete, Esther"
Now showing items 21-26 of 26
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Pd(II)-Catalyzed Fujiwara-Moritani Reactions for the Synthesis and Functionalization of Substituted Coumarins.
Ortiz de Elguea Flecha, Verónica; Carral Menoyo, Asier; Simón Vidal, Lorena; Martínez Nunes, Mikel ; Barbolla Cuardrado, Iratxe; Lete, Marta G.; Sotomayor Anduiza, María Nuria; Lete Expósito, María Esther (American Chemical Society, 2021-11-09)[EN]Highly substituted coumarins, privileged and versatile scaffolds for bioactive natural products and fluorescence imaging, are obtained via a Pd(II)-catalyzed direct C–H alkenylation reaction (Fujiwara–Moritani reaction), ... -
Perturbation Theory Model of Reactivity and Enantioselectivity of Palladium-catalyzed Heck-Heck cascade reactions
Blázquez Barbadillo, Cristina; Aranzamendi Uruburu, Eider; Coya Díaz de Sarralde, Estibaliz; Lete Expósito, María Esther; Sotomayor Anduiza, María Nuria; González Díaz, Humberto (Royal Society of Chemistry, 2016-04-13)Enantioselective intramolecular Heck-Heck cascade reactions have emerged as an excellent tool for the construction of polycyclic frameworks, such as Lycorane alkaloids, Xestoquinone and analogues. However, it is particularly ... -
Perturbation-Theory and Machine Learning (PTML). Model for High-Throughput Screening of Parham Reactions: Experimental and Theoretical Studies
Simón Vidal, Lorena; García Calvo, Oihane; Oteo, Uxue; Arrasate Gil, Sonia; Lete Expósito, María Esther; Sotomayor Anduiza, María Nuria; González Díaz, Humberto (American Chemical Society, 2018-06-13)Machine Learning (ML) algorithms are gaining importance in the processing of chemical information and modelling of chemical reactivity problems. In this work, we have developed a PTML model combining Perturbation-Theory ... -
Phenolic Activation in Chiral Brønsted Acid-Catalyzed Intramolecular α‑Amidoalkylation Reactions for the Synthesis of Fused Isoquinolines
Aranzamendi Uruburu, Eider; Sotomayor Anduiza, María Nuria; Lete Expósito, María Esther (ACS, 2017-06-16)An organolithium addition−intramolecular α- amidoalkylation sequence on N-phenethylimides has been developed for the synthesis of fused tetrahydroisoquinoline systems using 1,1′-bi-2-naphthol (binol)-derived Brønsted acids. ... -
Selective Pd(II)-catalyzed Acylation of Pyrrole with Aldehydes. Application to the Synthesis of Celastramycin analogues and Tolmetin
Santiago Alvarez, Carlos; Rubio, Ibon; Sotomayor Anduiza, María Nuria; Lete Expósito, María Esther (Wiley-VCH, 2020-04-27)The Pd(II)-catalyzed C-2 acylation of pyrrole with aldehydes in the presence of TBHP as oxidant has been studied for the synthesis of di(hetero)aryl ketones. The use of 2-pyrimidine as directing group leads to 2-acylpyrroles ... -
Transition metal-guanidine complexes as catalysts in organic reactions. Recent developments
Barbolla Cuadrado, Iratxe; Sotomayor Anduiza, María Nuria; Lete Expósito, María Esther (ARKAT USA, 2020-07-28)Guanidines have received great attention due to their application as superbasic proton sponges and organocatalysts, as well as excellent N-donor ligands able to coordinate with different metals. The introduction of ...