Now showing items 4792-4811 of 10647

    • Thumbnail

      Human DenPulp Stem Cells Grown in Neurogenic Media Differentiate Into Endothelial Cells and Promote Neovasculogenesis in the Mouse Brain 

      Luzuriaga González, Jon ORCID; Pastor Alonso, Oier; Encinas Pérez, Juan Manuel; Unda Rodríguez, Fernando José ORCID; Ibarretxe Bilbao, Gaskon ORCID; Pineda Martí, José Ramón ORCID (Frontiers Media, 2019-03-28)
      Dental pulp stem cells (DPSCs) have the capacity to give rise to cells with neuronal-like phenotypes, suggesting their use in brain cell therapies. In the present work, we wanted to address the phenotypic fate of adult ...
    • Thumbnail

      Human Early Life Exposome (HELIX) study: a European population-based exposome cohort 

      Maitre, Léa; De Bont, Jeroen; Casas, Maribel; Robinson, Oliver; Aasvang, Gunn Marit; Agier, Lydiane; Andrušaitytė, Sandra; Ballester, Ferrán; Basagaña, Xavier; Borrás, Eva; Brochot, Céline; Bustamante, Mariona; Carracedo, Angel; De Castro, Montserrat; Dedele, Audrius; De Castro, Montserrat; Dedele, Audrius; Donaire González, David; Estivill, Xavier; Evandt, Jorunn; Fossati, Serena; Giorgis Allemand, Lise; Granum, Berit; Grazuleviciene, Regina; Gützkow, Kristine Bjerve; Småstuen Haug, Line; Hernández Ferrer, Carles; Heude, Barbara; Ibarluzea Maurolagoitia, Jesús María; Julvez, Jordi; Karachaliou, Marianna; Keun, Hector C; Hjertager Krog, Norun; Lau, Chung-Ho E.; Leventakou, Vasiliki; Lyon Caen, Sarah; Manzano, Cyntia; Mason, Dan; McEachan, Rosemary; Meltzer, Helle Margrete; Petraviciene, Inga; Quentin, Joane; Roumeliotaki, Theano; Sabido, Eduard; Saulnier, Pierre-Jean; Siskos, Alexandros P; Siroux, Valérie; Sunyer, Jordi; Tamayo, Ibon; Urquiza, Jose; Vafeiadi, Marina; Van Gent, Diana; Vives Usano, Marta; Waiblinger, Dagmar; Warembourg, Charline; Chatzi, Leda; Coen, Muireann; Van den Hazel, Peter; Nieuwenhuijsen, Mark J.; Slama, Rémy; Thomsen, Cathrine; Wright, John; Vrijheid, Martine (BMJ, 2018-09)
      Purpose Essential to exposome research is the collection of data on many environmental exposures from different domains in the same subjects. The aim of the Human Early Life Exposome (HELIX) study was to measure and describe ...
    • Thumbnail

      Human Endogenous Retrovirus HERV-Fc1 Association with Multiple Sclerosis Susceptibility: A Meta-Analysis 

      De la Hera, Belén; Varadé, Jezabel; García-Montojo, Marta; Alcina, Antonio; Fedetz, María; Alloza Moral, Iraide; Astobiza Pérez, Janire; Leyva, Laura; Fernández, Óscar; Izquierdo, Guillermo; Rodríguez-Antigüedad Zarranz, Alfredo; Arroyo, Rafael; Álvarez-Lafuente, Roberto; Vandenbroeck, Koen; Matesanz, Fuencisla; Urcelay, Elena (Public Library Science, 2014-03-03)
      Background: Human endogenous retroviruses (HERVs) are repetitive sequences derived from ancestral germ-line infections by exogenous retroviruses and different HERV families have been integrated in the genome. HERV-Fc1 in ...
    • Thumbnail

      Human Hair Follicle-Derived Mesenchymal Stromal Cells from the Lower Dermal Sheath as a Competitive Alternative for Immunomodulation 

      Hernaez Estrada, Beatriz; González Pujana, Ainhoa; Cuevas, Andoni; Izeta Permisán, Ander ORCID; Spiller, Kara L.; Igartua Olaechea, Manuela ORCID; Santos Vizcaíno, Edorta ORCID; Hernández Martín, Rosa María ORCID (MDPI, 2022-01-24)
      Mesenchymal stromal cells (MSCs) have unique immunomodulatory capacities. We investigated hair follicle-derived MSCs (HF-MSCs) from the dermal sheath, which are advantageous as an alternative source because of their ...
    • Thumbnail

      Human LDL Structural Diversity Studied by IR Spectroscopy 

      Fernández Higuero, José Ángel; Salvador, Ana M.; Martín Plágaro, César Augusto; González Milicua, José Carlos; Rodríguez Arrondo, José Luis (Public Library Science, 2014-03-18)
      Lipoproteins are responsible for cholesterol traffic in humans. Low density lipoprotein (LDL) delivers cholesterol from liver to peripheral tissues. A misleading delivery can lead to the formation of atherosclerotic plaques. ...
    • Thumbnail

      Human metapneumovirus as cause of severe community-acquired pneumonia in adults: insights from a ten-year molecular and epidemiological analysis 

      Vidaur, Loreto; Totorika, Izarne; Montes, Milagrosa; Vicente Anza, Diego; Rello, Jordi; Cilla Eguiluz, Carlos Gustavo (Springer, 2019-07-24)
      BackgroundInformation on the clinical, epidemiological and molecular characterization of human metapneumovirus in critically ill adult patients with severe community-acquired pneumonia (CAP) and the role of biomarkers ...
    • Thumbnail

      Human mitochondrial DNA is extensively methylated in a non-CpG context 

      Patil, Vibha; Cuenin, Cyrille; Chung, Felicia; Rodríguez Aguilera, Jesús R.; Fernández Jiménez, Nora ORCID; Romero Garmendia, Irati; Bilbao Catalá, José Ramón ORCID; Cahais, Vincent; Rothwell, Joseph; Herceg, Zdenko (Oxford University Press, 2019-09-06)
      Mitochondrial dysfunction plays critical roles in cancer development and related therapeutic response; however, exact molecular mechanisms remain unclear. Recently, alongside the discovery of mitochondrial-specific DNA ...
    • Thumbnail

      Human Papillomavirus (HPV) genotype 18 variants in patients with clinical manifestations of HPV related infections in Bilbao, Spain 

      Arroyo, Sara L.; Basaras Ibarzabal, Miren ORCID; Arrese Arratibel, Miren Elixabete ORCID; Hernáez, Silvia; Andia Ortiz, Daniel; Esteban, Valetín; García Etxebarria, Koldo; Jugo Orrantia, Begoña Marina ORCID; Cisterna Cáncer, Ramón (BioMed Central, 2012)
      Background:Human papillomavirus (HPV) variants differ in their biological and chemical properties, and therefore, may present differences in pathogenicity. Most authors classified variants based on the phylogenetic analysis ...
    • Thumbnail

      Human resources information in the Management Report of the top Spanish companies 

      Saitua Iribar, Ainhoa; Andicoechea Arondo, Miren Lorea ORCID; Albizu Gallastegi, Eneka ORCID (Elsevier, 2014-01-22)
      Since 2005 in Spain it has been mandatory to include information about human resources in the Management Reports, provided it is relevant to understanding business evolution. We study the human resources (HR) disclosure ...
    • Thumbnail

      Human Sperm Testicular Angiotensin Converting Enzyme Helps Determine Human Embryo Quality 

      Gianzo Citores, Marta; Urizar Arenaza, Itziar ORCID; Muñoa Hoyos, Iraia ORCID; Larreategui, Zaloa; Garrido, Nicolás; Casis Sáenz, Luis; Irazusta Astiazaran, Jon ORCID; Subirán Ciudad, Nerea ORCID (Wolters Kluwer Medknow, 2018-06-05)
      Angiotensin-converting enzyme functions in the male reproductive system, but the extent of its function in reproduction is not fully understood. The primary objective of this work was to investigate the relationship between ...
    • Thumbnail

      HUMANISE: Human-Inspired Smart Management, towards a Healthy and Safe Industrial Collaborative Robotics 

      López de Ipiña Peña, Miren Karmele; Iradi Arteaga, Jon; Fernández Gómez de Segura, Elsa; Calvo, Pilar M.; Salle, Damien; Poologaindran, Anujan; Villaverde, Iván; Daelman, Paul; Sánchez Tapia, Emilio José; Requejo Rodríguez, Catalina ORCID; Suckling, John (MDPI, 2023-01-19)
      The workplace is evolving towards scenarios where humans are acquiring a more active and dynamic role alongside increasingly intelligent machines. Moreover, the active population is ageing and consequently emerging risks ...
    • Thumbnail

      Humanism after the Spanish Civil War: Gernika (1945-53), a Humanities and Social Sciencesbasque magazine 

      Ortiz de Pinedo, Aitor (2016-01-20)
      Espainiako Gerra Zibilaren eta II. Mundu Gerrarren ostean Gerra Hotza heldu zen. Testuinguru larri horretan humanismoan ikusi zuten hainbatek zibilizazio-krisiari irtenbidea topatzeko bidea. Gernika aldizkariak (1945-53) ...
    • Thumbnail

      Humor gráfico en la web. Aproximación descriptiva a los dibujantes de la ciber prensa en Euskadi 

      Castañeda Zumeta, Aitor (Fundación Sancho el Sabio, 2020-12-07)
      El presente artículo pretende una análisis descriptivo de la localización y visualidad otorgada al humor gráfico por parte de los diarios digitales vascos de mayor alcance y difusión. A través de un minucioso sistema de ...
    • Thumbnail

      Humoral Immunity Links Candida albicans Infection and Celiac Disease 

      Corouge, Marion; Loridant, Severine; Fradin, Chantal; Salleron, Julia; Damiens, Sebastien; Moragues Tosantos, María Dolores ORCID; Souplet, Vianney; Jouault, Thierry; Robert, Raymond; Dubucquoi, Sylvain; Sendid, Boualem; Poulain, Danie; Colombel, Jean Frederic (Public Library of Science, 2015-03-20)
      Objective The protein Hwp1, expressed on the pathogenic phase of Candida albicans, presents sequence analogy with the gluten protein gliadin and is also a substrate for transglutaminase. This had led to the suggestion ...
    • Thumbnail

      HuR/ELAVL1 drives malignant peripheral nerve sheath tumor growth and metastasis 

      Palomo Irigoyen, Marta; Pérez Andrés, Encarni; Iruarrizaga Lejarreta, Marta; Barreira Manrique, Adrián; Tamayo Caro, Miguel; Vila Vecilla, Laura; Moreno Cugnon, Leire; Beitia, Nagore; Medrano, Daniela; Fernández Ramos, David; Lozano, Juan José; Okawa, Satoshi; Lavín, José L.; Martín Martín, Natalia; Sutherland, James D.; Guitiérez de Juan, Virginia; González López, Monika; Macías Cámara, Nuria; Mosén Ansorena, David; Laraba, Liyam; Hanemann, C. Oliver; Ercolano, Emanuela; Parkinson, David B.; Schultz, Christopher W.; Araúzo Bravo, Marcos J.; Ascensión, Alex M.; Gerovska, Daniela; Iribar López, Haizea; Izeta Permisán, Ander ORCID; Pytel, Peter; Krastel, Philipp; Provenzani, Alessandro; Seneci, Pierfausto; Carrasco, Ruben D.; Del Sol, Antonio; Martínez Chantar, María Luz ORCID; Barrio Olano, María Rosa; Serra, Eduard; Lazaro, Conxi; Flanagan, Adrienne M.; Gorospe, Myriam; Ratner, Nancy; Aransay Bañares, Ana María; Carracedo Pérez, Arkaitz ORCID; Varela Rey, Marta; Woodhoo, Ashwin (The American Society for Clinical Investigation, 2020-07-01)
      Cancer cells can develop a strong addiction to discrete molecular regulators, which control the aberrant gene expression programs that drive and maintain the cancer phenotype. Here, we report the identification of the ...
    • Thumbnail

      Hutsune bizkarroiak eta sasi-A’-kateak 

      Duguine Haristoy, Maia ORCID (IKER UMR 5478, 2013)
      Gehienetan arrunt bereizirik aztertzen diren bi espresio isil, argumentu isilak eta nz-mugimenduaren aztarnak (hots, kopia isilduak), modu bateratuan aztertzearen alde egiten dut lan honetan. Horretarako, bi kategoria hauen ...
    • Thumbnail

      Hvad de skrifva i tidningare i Stockholm” Prensa y opinión pública en Suecia ante la emigración temprana a América (1861-1865) 

      Álvarez Gila, Óscar ORCID (Universidade Federal de São Paulo, 2017-12)
      Este artículo analiza el modo en el que la prensa sueca presentó la emigración a América en el periodo comprendido entre 1861 y 1865, es decir, en los años de la Guerra Civil en Estados Unidos. Este país comenzaba a ser, ...
    • Thumbnail

      Hyaluronic Acid Combined with Serum Rich in Growth Factors in Corneal Epithelial Defects 

      Suárez Barrio, Carlota; Etxebarria, Jaime; Hernáez Moya, Raquel; Del Val Alonso, Marina; Rodríguez Astigarraga, Maddalen; Urkaregi Etxepare, Arantza; Freire Vallejo, Vanesa; Morales González, María Celia; Durán de la Colina, Juan Antonio; Vicario, Marta; Molina, Irene; Herrero Vanrell, Rocío; Andollo Victoriano, María Noelia ORCID (MDPI, 2019-04-03)
      The aim of this study is to assess if an adhesive biopolymer, sodium hyaluronate (NaHA), has synergistic effects with s-PRGF (a serum derived from plasma rich in growth factors and a blood derivative that has already shown ...
    • Thumbnail

      Hyaluronic acid-based nanoplatforms for Doxorubicin: A review of stimuli-responsive carriers, co-delivery and resistance suppression 

      Ashrafizadeh, Milad; Mirzaei, Sepideh; Gholami, Mohammad Hossein; Hashemi, Farid; Zabolian, Amirhossein; Raei, Mehdi; Hushmandi, Kiavash; Zarrabi, Ali; Voelcker, Nicolas H.; Aref, Amir Reza; Hamblin, Michael R.; Varma, Rajender S.; Samarghandian, Saeed; Arostegi, I. J.; Alzola, M.; Kumar, Alan Prem; Thakur, Vijay Kumar; Nabavi, Noushin; Makvandi, Pooyan; Tay, Franklin R.; Orive Arroyo, Gorka (Elsevier, 2021-11-15)
      [EN]An important motivation for the use of nanomaterials and nanoarchitectures in cancer therapy emanates from the widespread emergence of drug resistance. Although doxorubicin (DOX) induces cell cycle arrest and DNA damage ...
    • Thumbnail

      Hybrid 3D Printed and Electrospun Multi-Scale Hierarchical Polycaprolactone Scaffolds to Induce Bone Differentiation 

      González Pujana, Ainhoa; Carranza Fernandino, Teresa; Santos Vizcaíno, Edorta ORCID; Igartua Olaechea, Manuela ORCID; Guerrero Manso, Pedro Manuel ORCID; Hernández Martín, Rosa María ORCID; De la Caba Ciriza, María Coro ORCID (MDPI, 2022-12-19)
      Complex scaffolds composed of micro- and nano-structures are a key target in tissue engineering and the combination of sequential 3D printing and electrospinning enables the fabrication of these multi-scale structures. In ...