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Now showing items 6437-6456 of 10661
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Molecular dynamics simulations of the calmodulin-induced α-helix in the SK2 calcium-gated potassium ion channel
; ; ; ; Núñez Viadero, Eider
; ; ; (Elsevier, 2023-02)
The family of small-conductance Ca2+-activated potassium ion channels (SK channels) is composed of four members (SK1, SK2, SK3, and SK4) involved in neuron-firing regulation. The gating of these channels depends on the ... -
Molecular Epidemiology, Antimicrobial Surveillance, and PK/PD Analysis to Guide the Treatment of Neisseria gonorrhoeae Infections
; ; ; ; Martínez Ballesteros, Ilargi; ; Garaizar Candina, Javier ; (MDPI, 2021-10-15)
The aim of this study was to apply molecular epidemiology, antimicrobial surveillance, and PK/PD analysis to guide the antimicrobial treatment of gonococci infections in a region of the north of Spain. Antibiotic susceptibility ... -
Molecular Identification of Fungal Species through Multiplex-qPCR to Determine Candidal Vulvovaginitis and Antifungal Susceptibility
Arrieta Aguirre, Inés; ; Carrano, Giulia ; ; ; Moragues Tosantos, María Dolores (MDPI, 2023-11-27)
Vulvovaginal candidiasis (VVC) is a prevalent condition affecting women worldwide. This study aimed to develop a rapid qPCR assay for the accurate identification of VVC etiological agents and reduced azole susceptibility. ... -
Molecular investigation and description of Iberozospeum n. gen., including the description of one new species (Eupulmonata, Ellobioidea, Carychiidae)
(Springer, 2022)[EN] The subterranean realm of the Cantabrian-Pyrenean region of northern Spain harbours a rich diversity of Zospeum. Due to their tiny size and the difficulty of finding them alive, scarce animal material has been available ... -
Molecular markers of oocyte differentiation in European eel during hormonally induced oogenesis
Rojo Bartolomé, Iratxe; ; ; ; ; ; (Elsevier, 2017-09-01)
Reproduction in captivity is a key study issue in Anguilla anguilla as a possible solution for its dwindling population. Understanding the mechanisms controlling the production of ribosomal building blocks during artificially ... -
Molecular Mechanisms Regulating the DNA Repair Protein APE1: A Focus on Its Flexible N-Terminal Tail Domain
López Jiménez, David; Rodríguez Pérez, José Antonio ; Bañuelos Rodríguez, Sonia (MDPI, 2021-06-11)
APE1 (DNA (apurinic/apyrimidinic site) endonuclease 1) is a key enzyme of one of the major DNA repair routes, the BER (base excision repair) pathway. APE1 fulfils additional functions, acting as a redox regulator of ... -
Molecular nanoribbon gels
; Dubey, Rajeev K.; ; ; ; ; Mateo Alonso, Aurelio (Royal Society of Chemistry, 2022-08)
Herein, we show that twisted molecular nanoribbons with as many as 322 atoms in the aromatic core are efficient gelators capable of self-assembling into ordered pi-gels with morphologies and sol-gel transitions that vary ... -
Molecular Optomechanics Approach to Surface-Enhanced Raman Scattering
(American Chemical Society, 2022)[EN] CONSPECTUS: Molecular vibrations constitute one of the smallest mechanical oscillators available for micro-/nanoengineering. The energy and strength of molecular oscillations depend delicately on the attached specific ... -
Molecular phylogeny of the genus Chondrina (Gastropoda, Panpulmonata, Chondrinidae) in the Iberian Peninsula.
Somoza Valdeolmillos, Eder; ; Caro Aramendia, Amaia ; Chueca Simón, Luis Javier ; Martínez Ortí, Alberto ; Puente Martínez, Ana Isabel ; (Elsevier, 2022-07)
[EN] Chondrina Reichenbach, 1828 is a highly diverse genus of terrestrial molluscs currently including 44 species with about 28 subspecific taxa. It is distributed through North Africa, central and southern Europe, from ... -
Molecular Recognition in C-Type Lectins: The Cases of DC- SIGN, Langerin, MGL, and L-Sectin
Valverde, Pablo; Martínez, J. Daniel; Cañada, F. Javier; Ardá, Ana; Jiménez Barbero, Jesús (2020-11-02)
Carbohydrates play a pivotal role in intercellular communication processes. In particular, glycan antigens are key for sustaining homeostasis, helping leukocytes to distinguish damaged tissues and invading pathogens from ... -
Molecular recognition of a membrane-anchored HIV-1 pan-neutralizing epitope.
Torralba Iturbe, Johana; De la Arada Echevarría, Igor ; ; ; ; ; ; ; ; ; ; Apellaniz Unzalu, Beatriz ; ; (Nature, 2022)
Antibodies against the carboxy-terminal section of the membrane-proximal external region (C-MPER) of the HIV-1 envelope glycoprotein (Env) are considered as nearly pan-neutralizing. Development of vaccines capable of ... -
Molecular Recognition of Glycan-Bearing Glycomacromolecules Presented at Membrane Surfaces by Lectins: An NMR View
; ; ; ; ; ; ; ; ; ; Ardá, Ana; ; Jiménez Barbero, Jesús (American Chemical Society, 2023-05)
Lectin–glycan interactions are at the heart of a multitude of biological events. Glycans are usually presented in a multivalent manner on the cell surface as part of the so-called glycocalyx, where they interact with other ... -
Molecular Recognition of the Native HIV-1 MPER Revealed by STED Microscopy of Single Virions
Carravilla Palomanes, Pablo; Chojnacki, Jakub; Rujas Díez, Edurne; ; ; Waithe, Dominic; Apellaniz Unzalu, Beatriz ; Sicard, Taylor; Julien, Jean Philippe; Eggeling, Christian; (Springer, 2019-01-08)
Antibodies against the Membrane-Proximal External Region (MPER) of the Env gp41 subunit neutralize HIV-1 with exceptional breadth and potency. Due to the lack of knowledge on the MPER native structure and accessibility, ... -
Molecular Recognition, Transient Chirality and Sulfur Hydrogen Bonding in the Benzyl Mercaptan Dimer
Saragi, Rizalina Tama; Juanes, Marcos; Pinacho, Ruth; Rubio García, José Emiliano; Fernández González, José Andrés; Lesarri, Alberto (MDPI, 2021-10-26)
The homodimers of transiently chiral molecules offer physical insight into the process of molecular recognition, the preference for homo or heterochiral aggregation and the nature of the non-covalent interactions stabilizing ... -
Molecular ruler mechanism and interfacial catalysis of the integral membrane acyltransferase PatA
; ; ; ; ; ; ; ; ; Contreras Gómez, Xabier; ; ; ; ; ; ; (American Association for the Advancement of Science, 2021-10)
[EN]Glycolipids are prominent components of bacterial membranes that play critical roles not only in maintaining the structural integrity of the cell but also in modulating host-pathogen interactions. PatA is an essential ... -
Molecular Signature of Aluminum Hydroxide Adjuvant in Ovine PBMCs by Integrated mRNA and microRNA Transcriptome Sequencing
Varela Martínez, Endika; Abendaño Carbajo, Naiara ; Asín, Javier; Sistiaga Poveda, Maialen; Pérez, Marta Maria; Reina, Ramsés; De Andrés, Damián; Luján, Lluís; Jugo Orrantia, Begoña Marina (Frontiers Media, 2018-10-23)
There have been few in vivo studies on the effect of aluminum hydroxide adjuvant and its influence on the immune response to vaccination. In this study, lambs received a parallel subcutaneous treatment with either commercial ... -
Molecular Techniques for Dicistrovirus Detection without RNA Extraction or Purification
Querido, Jailson F. B.; Agirre, Jon; Martí, Gerardo A.; Guerín Aguilar, Diego Marcelo A.; Silva, Marcelo Sousa (Hindawi Publishing Corporation, 2013)
Dicistroviridae is a new family of small, nonenveloped, and +ssRNA viruses pathogenic to both beneficial arthropods and insect pests as well. Triatoma virus (TrV), a dicistrovirus, is a pathogen of Triatoma infestans ... -
Molecular Weight Enables Fine-Tuning the Thermal and Dielectric Properties of Polymethacrylates Bearing Sulfonyl and Nitrile Groups as Dipolar Entities
(MDPI, 2021-01-20)In this work, polymethacrylates containing sulfonyl and nitrile functional groups were successfully prepared by conventional radical polymerization and reversible addition-fragmentation chain-transfer polymerization (RAFT). ... -
Molecular-Level Insight into Charge Carrier Transport and Speciation in Solid Polymer Electrolytes by Chemically Tuning Both Polymer and Lithium Salt
; ; ; ; ; ; ; Manzano Moro, Hegoi; ; ; (American Chemical Society, 2023-01)
The advent of Li-metal batteries has seen progress toward studies focused on the chemical modification of solid polymer electrolytes, involving tuning either polymer or Li salt properties to enhance the overall cell ... -
Molecularly Imprinted Polymer-Based Sensors for the Detection of Skeletal- and Cardiac-Muscle-Related Analytes
(MDPI, 2023-06-15)Molecularly imprinted polymers (MIPs) are synthetic polymers with specific binding sites that present high affinity and spatial and chemical complementarities to a targeted analyte. They mimic the molecular recognition ...