Now showing items 21-40 of 224

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      Anti-TNFα treatment in Crohn’s disease: Impact on hepatic steatosis, gut-derived hormones and metabolic status 

      Manka, Paul; Sydor, Svenja; Wase, Nishikant; Best, Jan; Brandenburg, Malte; Hellbeck, Annika; Schänzer, Julia; Vilchez-Vargas, Ramiro; Link, Alexander; Figge, Anja; Jähnert, Andreas; Von Arnim, Ulrike; Coombes, Jason D.; Cubero, Francisco-Javier; Kahraman, Alisan; Kim, Moon-Sung; Kälsch, Julia; Kinner, Sonja; Faber, Klaas-Nico; Moshage, Han; Gerken, Guido; Syn, Wing-Kin; Friedman, Scott L.; Canbay, Ali; Bechmann, Lars P. (Wiley, 2021-11)
      Background and Aims An association between Crohn's disease (CD) and hepatic steatosis has been reported. However, the underlying mechanisms of steatosis progression in CD are not clear. Among the most effective CD treatments ...
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      Application of Bioactive Thermal Proteome Profiling to Decipher the Mechanism of Action of the Lipid Lowering 13(2)-Hydroxy-pheophytin Isolated from a Marine Cyanobacteria 

      Carrasco del Amor, Ana María; Freitas, Sara; Urbatzka, Ralph; Fresnedo Aranguren, María Olatz; Cristobal Barragán, Susana (MDPI, 2019-06-21)
      The acceleration of the process of understanding the pharmacological application of new marine bioactive compounds requires identifying the compound protein targets leading the molecular mechanisms in a living cell. The ...
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      Association of Birth Order with Cardiovascular Disease Risk Factors in Young Adulthood: A Study of One Million Swedish Men 

      Jelenkovic Moreno, Aline; Silventoinen, Karri; Tynelius, Per; Myrskylae, Mikko; Rasmussen, Finn (Public Library of Science, 2013-05-16)
      Background: Birth order has been suggested to be linked to several cardiovascular disease (CVD) risk factors, but the evidence is still inconsistent. We aim to determine the associations of birth order with body mass index ...
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      Association of Current and Former Smoking With Body Mass Index: a Study of Smoking Discordant Twin Pairs From 21 Twin Cohorts 

      Piirtola, Maarit; Jelenkovic Moreno, Aline; Latvala, Antti; Sund, Reijo; Honda, Chika; Inui, Fujio; Watanabe, Mikio; Tomizawa, Rie; Iwatani, Yoshinori; Ordoñana Martín, Juan Ramón; Sánchez Romera, Juan Francisco; Colodro Conde, Lucia; Tarnoki, Adam D.; Tarnoki, David L.; Martin, Nicholas G.; Montgomery, Grant W.; Medland, Sarah E.; Rasmussen, Finn; Tynelius, Per; Tan, Qihua; Zhang, Dongfeng; Pang, Zengchang; Rebato Ochoa, Esther Matilde ORCID; Stazi, Maria A.; Fagnani, Corrado; Brescianini, Sonia; Busjahn, Andreas; Harris, Jennifer R.; Brandt, Ingunn; Nilsen, Thomas Sevenius; Cutler, Tessa L.; Hopper, John L.; Corley, Robin P.; Huibregtse, Brooke M.; Sung, Joohon; Kim, Jina; Lee, Jooyeon; Lee, Sooji; Gatz, Margaret; Butler, David A.; Franz, Carol E.; Kremen, William S.; Lyons, Michael J.; Magnusson, Patrik K. E.; Pedersen, Nancy L.; Aslan, Anna K. Dahl; Oncel, Sevgi Y.; Aliev, Fazil; Derom, Catherine A.; Vlietinck, Robert F.; Loos, Ruth J. F.; Silberg, Judy L.; Maes, Hermine H.; Boomsma, Dorret I.; Sorensen, Thorkild I. A.; Korhonen, Tellervo; Kaprio, Jaakko; Silventoinen, Karri (Public Library Science, 2018-07-12)
      Background Smokers tend to weigh less than never smokers, while successful quitting leads to an increase in body weight. Because smokers and non-smokers may differ in genetic and environmental family background, we ...
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      Associations Between Birth Size and Later Height From Infancy Through Adulthood: an Individual Based Pooled Analysis of 28 Twin Cohorts Participating in the Codatwins Project 

      Jelenkovic Moreno, Aline; Yokoyama, Yoshie; Sund, Reijo; Hur, Yoon-Mi; Harris, Jennifer R.; Brandt, Ingunn; Nilsen, Thomas Sevenius; Ooki, Syuichi; Ullemar, Vilhelmina; Almqvisth, Catarina; Magnusson, Patrik K. E.; Saudino, Kimberly J.; Stazi, Maria A.; Fagnani, Corrado; Brescianini, Sonia; Nelson, Tracy L.; Whitfield, Keith E.; Knafo Noam, Ariel; Mankuta, David; Abramson, Lior; Cutler, Tessa L.; Hopper, John L.; Llewellyn, Clare H.; Fisher, Abigail; Corley, Robin P.; Huibregtse, Brooke M.; Derom, Catherine A.; Vlietinck, Robert F.; Bjerregaard Andersen, Morten; Nielsen, Henning Beck; Sodemann, Morten; Krueger, Robert F.; McGue, Matt; Pahlen, Shandell; Burt, S. Alexandra; Klump, Kelly L.; Dubois, Lise; Boivin, Michel; Brendgen, Mara; Dionne, Ginette; Vitaro, Frank; Willemsen, Gonneke; Bartels, Meike; Van Beijsterveld, Catharina E. M.; Craig, Jeffrey M.; Saffery, Richard; Rasmussen, Finn; Tynelius, Per; Heikkila, Kauko; Pietilainen, Kirsi H.; Bayasgalan, Gombojav; Narandalai, Danshiitsoodol; Haworth, Claire M. A.; Plomin, Robert; Ji, Fuling; Ning, Feng; Pang, Zengchang; Rebato Ochoa, Esther Matilde ORCID; Tarnoki, Adam D.; Tarnoki, David L.; Kim, Jina; Lee, Jooyeon; Lee, Sooji; Sung, Joohon; Loos, Ruth J. F.; Boomsma, Dorret I.; Sorensen, Thorkild I. A.; Kaprio, Jaakko; Silventoinen, Karri (Elsevier Ireland, 2018-05)
      Background: There is evidence that birth size is positively associated with height in later life, but it remains unclear whether this is explained by genetic factors or the intrauterine environment. Aim: To analyze the ...
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      Atorvastatin Provides a New Lipidome Improving Early Regeneration After Partial Hepatectomy in Osteopontin Deficient Mice 

      Núñez García, Maitane; Gómez Santos, Beatriz; Saenz de Urturi Indart, Diego; Mestre, Daniela; González Romero, Francisco; Buqué García, Xabier ORCID; Gutiérrez de Juan, Virginia; Martínez Chantar, María Luz ORCID; Syn, Wing-Kin; Fresnedo Aranguren, María Olatz; Aspichueta Celaá, Patricia (Nature Publishing Group, 2018-10-02)
      Osteopontin (OPN), a multifunctional cytokine that controls liver glycerolipid metabolism, is involved in activation and proliferation of several liver cell types during regeneration, a condition of high metabolic demands. ...
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      Autocrine regulation of human sperm motility by tachykinins 

      Pinto, Francisco M.; Ravina, Cristina G.; Subirán Ciudad, Nerea ORCID; Cejudo Román, Antonio; Fernández Sánchez, Manuel; Irazusta Astiazaran, Jon ORCID; Garrido, Nicolás; Candenas, Luz (BioMed Central, 2010)
      Background We examined the presence and function of tachykinins and the tachykinin-degrading enzymes neprilysin (NEP) and neprilysin-2 (NEP2) in human spermatozoa. Methods Freshly ejaculated semen was collected from ...
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      Banpirismoaren mitoa zientziaren argitan 

      Echeazarra, Leyre (Elhuyar, 2023-12-01)
      Ezaguna denez, mitoak jendeak mundua azaltzeko asmatu dituen istorioak dira. Banpirismoaren mitoa gizateria bezain zaharra da. Antzinatik XVIII. mendera arte, banpiroak izaki izugarri gaiztotzat hartzen ziren, eta beldur ...
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      Biluzik elurretan. 

      Echeazarra, Leyre (Elhuyar, 2021-07-21)
      2021. urte hau historikoa izaten ari da, ez bakarrik COVID-19aren pandemiagatik eta AEBko Kapitolioari eraso egin ziotelako, baita Filomena deituriko ekaitz gogorrak eragindako muturreko hotz-boladagatik ere. Zer pentsatuko ...
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      BIRC6 Is Associated with Vulnerability of Carotid Atherosclerotic Plaque 

      Alloza Moral, Iraide; Salegi, Andrea; Mena Lucía, Jorge; Tulloch Navarro, Raquel; Martín Plágaro, César Augusto; Aspichueta Celaá, Patricia; Martínez Salazar, Lucía; Uriarte Carpio, Jon; De la Hera Cagigal, Patricia; Vega Manrique, Reyes; Triviño, Juan Carlos; Freijo, María del Mar; Vandenbroeck, Koen (MDPI, 2020-12-09)
      Carotid atherosclerotic plaque rupture can lead to cerebrovascular accident (CVA). By comparing RNA-Seq data from vascular smooth muscle cells (VSMC) extracted from carotid atheroma surgically excised from a group of ...
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      Birth size and gestational age in opposite-sex twins as compared to same-sex twins: An individualbased pooled analysis of 21 cohorts 

      Jelenkovic Moreno, Aline; Sund, Reijo; Yokoyama, Yoshie; Hur, Yoon-Mi; Ullemar, Vilhelmina; Almqvist, Catarina; Magnusson, Patrik K. E.; Willemsen, Gonneke; Bartels, Meike; Van Beijsterveldt, Catharina EM; Bogl, Leonie H; Pietiläinen, Kirsi H; Vuoksimaa, Eero; Ji, Fuling; Ning, Feng; Pang, Zengchang; Nelson, Tracy L; Whitfield, Keith E.; Rebato Ochoa, Esther Matilde ORCID; Llewellyn, Clare H.; Fisher, Abigail; Bayasgalan, Gombojav; Narandalai, Danshiitsoodol; Bjerregaard-Andersen, Morten; Beck-Nielsen, Henning; Sodemann, Morten; Tarnoki, Adam D.; Tarnoki, David L.; Ooki, Syuichi; Stazi, Maria A.; Fagnani, Corrado; Brescianini, Sonia; Dubois, Lise; Boivin, Michel; Brendgen, Mara; Dionne, Ginette; Vitaro, Frank; Cutler, Tessa L.; Hopper, John L.; Krueger, Robert F.; McGue, Matt; Pahlen, Shandell; Craig, Jeffrey M.; Saffery, Richard; Haworth, Claire MA (Nature Publishing, 2018-04-19)
      It is well established that boys are born heavier and longer than girls, but it remains unclear whether birth size in twins is affected by the sex of their co-twin. We conducted an individual-based pooled analysis of 21 ...
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      Bone Health and Its Relationship with Impact Loading and the Continuity of Physical Activity throughout School Periods 

      Hervás Barbara, Gotzone; Ruiz Litago, Fátima ORCID; Irazusta Astiazaran, Jon ORCID; Irazusta Astiazaran, Amaya; Sanz Echevarría, María Begoña; Gil Goicouría, Francisco Javier ORCID; Fraile Bermúdez, Ana Belén; Pérez Rodrigo, Carmen ORCID; Zarrazquin Arizaga, Idoia (MDPI, 2019-08-14)
      Bone is influenced by physical activity (PA) throughout life, but childhood and adolescence provide a key opportunity to maximize peak bone mass. Thus, it is important to identify the relationship between PA practiced in ...
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      CaMKII modulates the cardiac transient outward K+ current through their association in non-caveolar membrane rafts 

      Alday, Aintzane; Ahyayauch, Hasna; Fernández López, Victor; Echeazarra Escudero, Leire; Urrutia Iñiguez, Janire; Casis Sáenz, Oscar ORCID; Gallego Muñoz, Mónica ORCID (University of Duisburg-Essen, 2020-01-15)
      Background/aims: To test whether the physiological regulation of the cardiac Kv4 channels by the Ca2+/calmodulin-dependent protein kinase II (CaMKII) is restricted to lipid rafts and whether the interactions observed in ...
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      Can Vitality and Mental Health Influence Upper Extremity Pain? A Prospective Cohort Study of 1185 Female Hospital Nurses 

      Núñez-Cortés, Rodrigo; Espin Elorza, Ander ORCID; Calatayud, Joaquín; Pérez-Alenda, Sofía; Cruz-Montecinos, Carlos; López-Bueno, Rubén; Vinstrup, Jonas; Jakobsen, Markus D.; Andersen, Lars Louis (MDPI, 2023-10-07)
      Musculoskeletal disorders of the upper extremity are among the most common occupational problems affecting nurses. The aim of this study was to analyze the prospective association between vitality and mental health and ...
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      Clinical Implications of (Pro)renin Receptor (PRR) Expression in Renal Tumours 

      Solano Iturri, Jon Danel; Echevarría Orella, Enrique ORCID; Unda Urzaiz, Jesús Miguel; Loizaga Iriarte, Ana; Pérez Fernández, Amparo; Angulo, Javier C.; López Fernández de Villaverde, José Ignacio ORCID; Larrinaga Embeita, Gorka ORCID (MDPI, 2021-02-10)
      (1) Background: Renal cancer is one of the most frequent malignancies in Western countries, with an unpredictable clinical outcome, partly due to its high heterogeneity and the scarcity of reliable biomarkers of tumour ...
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      Clinical progress in MSC-based therapies for the management of severe COVID-19. 

      Rosselló Gelabert, María; González Pujana, Ainhoa; Igartua Olaechea, Manuela ORCID; Santos Vizcaíno, Edorta ORCID; Hernández Martín, Rosa María ORCID (Elsevier, 2022-12)
      Considering the high impact that severe Coronavirus disease 2019 (COVID-19) cases still pose on public health and their complex pharmacological management, the search for new therapeutic alternatives is essential. Mesenchymal ...
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      Conformational Plasticity Underlies Membrane Fusion Induced by an HIV Sequence Juxtaposed to the Lipid Envelope 

      De la Arada Echevarría, Igor ORCID; Torralba Iturbe, Johana ORCID; Tascón, Igor; Colom Diego, Adai; Ubarrechena Belandia, Iván ORCID; Rodríguez Arrondo, José Luis; Apellaniz Unzalu, Beatriz ORCID; Nieva Escandón, José Luis (Springer Nature, 2021-01-14)
      Envelope glycoproteins from genetically-divergent virus families comprise fusion peptides (FPs) that have been posited to insert and perturb the membranes of target cells upon activation of the virus-cell fusion reaction. ...
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      Current Food Consumption amongst the Spanish ANIBES Study Population 

      Partearroyo Cediel, Teresa; Samaniego Vaesken, María de Lourdes; Ruiz, Emma; Aranceta Bartrina, Javier; Gil, Ángel; González Gross, Marcela; Ortega, Rosa M.; Serra Majem, Lluís; Varela Moreiras, Gregorio (MDPI, 2019-11)
      Dietary habits amongst the Spanish population are currently a relevant cause for concern, as macronutrient profiles and micronutrient intakes seem to be inadequate and globally moving away from the traditional Mediterranean ...
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      Deciphering the roles of triiodothyronine (T3) and thyroid stimulating hormone (TSH) on cardiac electrical remodeling in clinical and experimental hypothyroidism 

      Casis Sáenz, Oscar ORCID; Echeazarra, Leyre; Sáenz Díez, Beatriz; Gallego Muñoz, Mónica ORCID (Springer, 2024-02)
      Hypothyroidism is the most frequent endocrine pathology. Although clinical or overt hypothyroidism has been traditionally associated to low T3 / T4 and high thyrotropin (TSH) circulating levels, other forms exist such as ...
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      Delta and kappa opioid receptors in human endometrium during the menstrual cycle: Expression and localization 

      Olabarrieta López, Estíbaliz; Totorikaguena Iturriaga, Lide ORCID; Matorras Weinig, José Roberto; Aguirregoitia Marcos, Ekaitz; Aguirregoitia Marcos, Naiara ORCID (Elsevier, 2023-04)
      Objective Endogenous opioid peptides were reported to be involved in the regulation of reproductive physiology and their precursors and receptors were described in many of the male and female reproductive tissues. Mu ...