Now showing items 41-60 of 161

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      Development, Application and Evaluation of an Active Learning Methodology for Health Science Students, Oriented towards Equity and Cultural Diversity in the Treatment and Care of Geriatric Patients 

      Sánchez de Miguel, Manuel Norberto ORCID; Orkaizagirre Gomara, Aintzane; Izagirre Otaegi, Andrea; Ortiz de Elguea Díaz, Francisco Javier ORCID; Badiola Echaburu, Iker ORCID; Gómez Gastiasoro, Ainara (MDPI, 2022-11-06)
      The increased aging of populations and rises in immigration have prompted the design of new methodologies and instruments for fostering the invisible care of geriatric patients among health science students in accordance ...
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      Dexamethasone Protects Retinal Ganglion Cells But Not Muller Glia Against Hyperglycemia In Vitro 

      Pereiro Díez, Xandra ORCID; Ruzafa Andrés, Noelia ORCID; Acera Osa, Arantxa; Fonollosa Calduch, Alejandro; Rodríguez, Francisco David; Vecino Cordero, Elena ORCID (Public Library Science, 2018-11-26)
      Diabetic retinopathy (DR) is a common complication of diabetes, for which hyperglycemia is a major etiological factor. It is known that retinal glia (Muller cells) and retinal ganglion cells (RGCs) are affected by diabetes, ...
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      Differential Distribution of RBPMS in Pig, Rat, and Human Retina after Damage 

      Pereiro Díez, Xandra ORCID; Ruzafa Andrés, Noelia ORCID; Urcola Carrera, Javier Haritz ORCID; Sharma, Sansar C.; Vecino Cordero, Elena ORCID (MDPI, 2020-12-07)
      RNA binding protein with multiple splicing (RBPMS) is expressed exclusively in retinal ganglion cells (RGCs) in the retina and can label all RGCs in normal retinas of mice, rats, guinea pigs, rabbits, cats, and monkeys, ...
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      Discoidin Domain Receptor 2 Expression as Worse Prognostic Marker in Invasive Breast Cancer 

      Romayor Arredondo, Irene ORCID; Luque García Vaquero, Marina; Márquez Clavijo, Joana ORCID; Arteta Ruiz, Beatriz ORCID; Barceló Galíndez, José Ramón; Benedicto García, Aitor (Wiley, 2022)
      [EN] Discoidin domain receptor 2 (DDR2) is arising as a promising therapeutic target in breast carcinoma (BC). The ability of DDR2 to bind to collagen promotes protumoral responses in cancer cells that influence the tumor ...
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      Docosahexaenoic acid reduces cerebral damage and ameliorates long-term cognitive impairments caused by neonatal hypoxia-ischemia in rats 

      Arteaga Cabeza, Olatz; Revuelta Aramberri, Miren ORCID; Urigüen Echeverría, Leyre ORCID; Martínez Millán, Luis; Hilario Rodríguez, Enrique; Álvarez Díaz, Antonia Ángeles (Springer, 2011-10-29)
      As the interest in the neuroprotective possibilities of docosahexaenoic acid (DHA) for brain injury has grown in the recent years, we aimed to investigate the long-term effects of this fatty acid in an experimental model ...
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      Editorial: Tumor microenvironment in primary brain cancers 

      Niechi, Ignacio; Pineda Martí, José Ramón ORCID (Frontiers, 2023-01-24)
      Primary brain tumors are most commonly detected in the late stages of the disease and there are only a few treatment opportunities. Overall survival rates are significantly low and the response to chemo/radiotherapy is not ...
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      Effect of Hypoxia on the Retina and Superior Colliculus of Neonatal Pigs 

      Ruzafa Andrés, Noelia ORCID; Rey Santano, María Carmen; Mielgo, Victoria; Pereiro Díez, Xandra ORCID; Vecino Cordero, Elena ORCID (Public LIbrary Science, 2017-04-13)
      Purpose To evaluate the effect of hypoxia on the neonatal pig retina and brain, we analysed the retinal ganglion cells (RGCs) and neurons in the superior colliculus, as well as the response of astrocytes in both these ...
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      Effect of Neonatal Asphyxia on the Impairment of the Auditory Pathway by Recording Auditory Brainstem Responses in Newborn Piglets: A New Experimentation Model to Study the Perinatal Hypoxic-Ischemic Damage on the Auditory Syste 

      Álvarez, Francisco José; Revuelta Aramberri, Miren ORCID; Santaolalla Montoya, Francisco ORCID; Álvarez Díaz, Antonia Ángeles; Lafuente, Héctor; Arteaga Cabeza, Olatz; Alonso Alconada, Daniel ORCID; Sánchez del Rey, Ana Salomé; Hilario Rodríguez, Enrique; Martínez Ibargüen, Agustín (Public Library Science, 2015-05-26)
      Introduction Hypoxia-ischemia (HI) is a major perinatal problem that results in severe damage to the brain impairing the normal development of the auditory system. The purpose of the present study is to study the effect ...
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      Effect of resveratrol on alcohol-induced mortality and liver lesions in mice 

      Bujanda Fernández de Pierola, Luis ORCID; García Barcina, María; Gutiérrez de Juan, Virginia; Bidaurrazaga Van Dierdonck, Joseba; Fernández de Luco, Marian; Gutiérrez Stampa, María Angeles; Larzabal, Mikel; Hijona Muruamendiaraz, Elizabeth; Sarasqueta, Cristina; Echenique Elizondo, Miguel; Arenas Mirave, Juan Ignacio (BioMed Central, 2006-11-14)
      Background Resveratrol is a polyphenol with important antiinflammatory and antioxidant properties. We investigated the effect of resveratrol on alcohol-induced mortality and liver lesions in mice. Methods Mice were ...
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      Effects of Adult Müller Cells and Their Conditioned Media on the Survival of Stem Cell-Derived Retinal Ganglion Cells 

      Pereiro Díez, Xandra ORCID; Miltner, Adam M.; La Torre, Anna; Vecino Cordero, Elena ORCID (MDPI, 2020-07-22)
      Retinal neurons, particularly retinal ganglion cells (RGCs), are susceptible to the degenerative damage caused by different inherited conditions and environmental insults, leading to irreversible vision loss and, ultimately, ...
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      Effects of Cannabidiol, Hypothermia, and Their Combination in Newborn Rats with Hypoxic-Ischemic Encephalopathy 

      Álvarez Díaz, Francisco José; Álvarez Díaz, Antonia Ángeles; Rodríguez Arellano, José Julio; Lafuente, Héctor; Canduela Pérez, Miren Josune; Hind, William; Blanco Bruned, José Luis; Alonso Alconada, Daniel ORCID; Hilario Rodríguez, Enrique (Society for Neuroscience, 2023-04)
      Therapeutic hypothermia is well established as a standard treatment for infants with hypoxic-ischemic (HI) encephalopathy but it is only partially effective. The potential for combination treatments to augment hypothermic ...
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      Effects of Folinic Acid Administration on Lower Limb Ischemia/Reperfusion Injury in Rats 

      Cearra Guezuraga, Iñigo; Herrero de la Parte, Borja; Ruiz Montesinos, María Inmaculada ORCID; Alonso Varona, Ana Isabel; Moreno Franco, Diana Isabel; García-Alonso Montoya, Ignacio ORCID (MDPI, 2021-11-25)
      Surgery under ischemic conditions, lasting up to 3 h, is routinely performed in orthopedic surgery, causing undesirable injury due to ischemia-reperfusion syndrome, with short and medium-term functional repercussions. To ...
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      Elevation of Tear MMP-9 Concentration as a Biomarker of Inflammation in Ocular Pathology by Antibody Microarray Immunodetection Assays 

      De la Fuente López, Miguel; Rodríguez Agirretxe, Ignacio; Vecino Cordero, Elena ORCID; Astigarraga Arribas, Egoitz; Acera Osa, Arantxa; Barreda Gómez, Gabriel (MDPI, 2022-05-18)
      Matrix metalloproteinases are a family of enzymes fundamental in inflammatory processes. Between them, MMP-9 is up-regulated during inflammation; thus, its quantification in non-invasive fluids is a promising approach for ...
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      Enhanced Adipogenic Differentiation of Human Dental Pulp Stem Cells in Enzymatically Decellularized Adipose Tissue Solid Foams 

      Garcia Urkia, Nerea; Luzuriaga González, Jon ORCID; Uribe Etxebarria, Veronica; Irastorza Epelde, Igor ORCID; Fernandez San Argimiro, Francisco Javier; Olalde, Beatriz; Briz, Nerea; Unda Rodríguez, Fernando José ORCID; Ibarretxe Bilbao, Gaskon ORCID; Madarieta, Iratxe; Pineda Martí, José Ramón ORCID (MDPI, 2022-07-23)
      Engineered 3D human adipose tissue models and the development of physiological human 3D in vitro models to test new therapeutic compounds and advance in the study of pathophysiological mechanisms of disease is still ...
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      Enzyme Therapy: Current Challenges and Future Perspectives 

      De la Fuente López, Miguel; Lombardero, Laura; Gómez-González, Alfonso; Solari, Cristina; Angulo Barturen, Iñigo; Acera Osa, Arantxa; Vecino Cordero, Elena ORCID; Astigarraga, Egoitz; Barreda Gómez, Gabriel (MDPI, 2021-08-25)
      In recent years, enzymes have risen as promising therapeutic tools for different pathologies, from metabolic deficiencies, such as fibrosis conditions, ocular pathologies or joint problems, to cancer or cardiovascular ...
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      Estimation of preterm labor immediacy by nonlinear methods 

      Malaina Celada, Iker ORCID; Martínez Fernández, Luis ORCID; Matorras Weinig, José Roberto; Bringas Roldán, Carlos; Aranburu Laka, Larraitz; Fernández-Llebrez del Rey, Luis; González, Leire; Arana, Itziar; Pérez Pinilla, Martín Blas ORCID; Martínez de la Fuente Martínez, Ildefonso Abel (Public Library Science, 2017-06-01)
      Preterm delivery affects about one tenth of human births and is associated with an increased perinatal morbimortality as well as with remarkable costs. Even if there are a number of predictors and markers of preterm delivery, ...
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      Evaluation of bioactive sphingolipids in 4-HPR-resistant leukemia cells 

      Apraiz García, Aintzane ORCID; Idkowiak-Baldys, Jolanta K.; Boyano López, María Dolores ORCID; Pérez-Yarza Pérez-Irezabal, Gorka ORCID; Hannun, Yusuf A.; Asumendi Mallea, Aintzane ORCID (BioMed Central, 2011-10-07)
      Background -- N-(4-hydroxyphenyl)retinamide (4-HPR, fenretinide) is a synthetic retinoid with potent pro-apoptotic activity against several types of cancer, but little is known regarding mechanisms leading to chemoresistance. ...
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      Evidence of conditioned behavior in amoebae 

      Martínez de la Fuente Martínez, Ildefonso Abel; Bringas Roldán, Carlos; Malaina Celada, Iker ORCID; Fedetz, María; Carrasco Pujante, José; Morales, Miguel; Knafo Farhi, Dina Shira; Martínez Fernández, Luis ORCID; Pérez Samartín, Alberto Luis ORCID; López Fernández de Villaverde, José Ignacio ORCID; Pérez-Yarza Pérez-Irezabal, Gorka ORCID; Boyano López, María Dolores ORCID (Nature, 2019-08-15)
      Associative memory is the main type of learning by which complex organisms endowed with evolved nervous systems respond efficiently to certain environmental stimuli. It has been found in different multicellular species, ...
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      Expansion of Human Limbal Epithelial Stem/Progenitor Cells Using Different Human Sera: A Multivariate Statistical Analysis 

      Hernáez Moya, Raquel; González, Sheyla; Urkaregi Etxepare, Arantza; José Ignacio Pijoan Zubizarreta; Deng, Sophie X.; Andollo Victoriano, María Noelia ORCID (MDPI, 2020-07-25)
      Transplantation of human cultured limbal epithelial stem/progenitor cells (LESCs) has demonstrated to restore the integrity and functionality of the corneal surface in about 76% of patients with limbal stem cell deficiency. ...
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      Factibilidad de la utilización de la inteligencia artificial para el cribado de pacientes con COVID-19 en Paraguay 

      Galván, Pedro; Fusillo, José; González, Felipe; Vukujevic, Oraldo; Recalde, Luciano; Rivas, Ronald; Ortellado, José; Portillo, Juan; Borba, Julio; Hilario Rodríguez, Enrique (Pan American Health Organization, 2022)
      Objective. Study the feasibility of using artificial intelligence as a sensitive and specific method for COVID-19 screening in patients with respiratory conditions, using chest CT scan images and a telemedicine platform. ...