Browsing Artículos by Author "Cossío Arrieta, Unai"
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In vivo multimodal imaging of adenosine A1 receptors in neuroinflammation after experimental stroke
Joya, Ana; Ardaya Franco, María Isabel; Montilla López, Alejandro ; Garbizu, Maider; Plaza García, Sandra; Gómez Vallejo, Vanessa; Padró, Daniel; Gutiérrez Martín, Juan José; Ríos, Xabier; Ramos Cabrer, Pedro; Cossío Arrieta, Unai; Pulagam, Krishna Reddy; Higuchi, Makoto; Domercq García, María ; Cavaliere, Fabio; Matute Almau, Carlos José; Llop Roig, Jordi ; Martín Muñoz, Abraham (Ivyspring International Publisher, 2021)Adenosine A(l) receptors (A(l)ARs) are promising imaging biomarkers and targets for the treatment of stroke. Nevertheless, the role of A(l)ARs on ischemic damage and its subsequent neuroinflammatory response has been ... -
In vivo PET Imaging of Gliogenesis After Cerebral Ischemia in Rats
Ardaya Franco, María Isabel; Joya, Ana; Padró, Daniel; Plaza García, Sandra; Gómez Vallejo, Vanessa; Sánchez, Mercedes; Garbizu, Maider; Cossío Arrieta, Unai; Matute Almau, Carlos José; Cavaliere, Fabio; Llop Roig, Jordi ; Martín Muñoz, Abraham (Frontiers Media, 2020-07-30)In vivopositron emission tomography of neuroinflammation has mainly focused on the evaluation of glial cell activation using radiolabeled ligands. However, the non-invasive imaging of neuroinflammatory cell proliferation ... -
Longitudinal Evaluation of a Novel BChE PET Tracer as An Early In Vivo Biomarker in the Brain of a Mouse Model for Alzheimer Disease
Rejc, Luka; Gómez Vallejo, Vanessa; Joya, Ana; Moreno, Oscar; Egimendia Tolaretxipi, Ander; Castellnou Arenas, Pilar; Ríos Anglada, Xabier; Cossío Arrieta, Unai; Baz Maldonado, Zuriñe; Passannante, Rossana; Tobalina Larrea, Ignacio; Ramos Cabrer, Pedro; Giralt, Albert; Sastre, Magdalena; Capetillo González de Zarate, Estibaliz; Košak, Urban; Knez, Damijan; Gobec, Stanislav; Marder, Mariel; Martín Muñoz, Abraham; Llop Roig, Jordi (Ivyspring International Publisher, 2021-04-26)Purpose: The increase in butyrylcholinesterase (BChE) activity in the brain of Alzheimer disease (AD) patients and animal models of AD position this enzyme as a potential biomarker of the disease. However, the information ... -
Longitudinal evaluation of neuroinflammation and oxidative stress in a mouse model of Alzheimer disease using positron emission tomography
Rejc, Luka; Gómez Vallejo, Vanessa; Joya, Ana; Arsequell, Gemma; Egimendia Tolaretxipi, Ander; Castellnou Arenas, Pilar; Ríos Anglada, Xabier; Cossío Arrieta, Unai; Baz Maldonado, Zuriñe; Iglesias, Leyre; Capetillo González de Zarate, Estibaliz; Ramos Cabrer, Pedro; Martín Muñoz, Abraham; Llop Roig, Jordi (BMC, 2022)[EN] Background: Validation of new biomarkers of Alzheimer disease (AD) is crucial for the successful development and implementation of treatment strategies. Additional to traditional AT(N) biomarkers, neuroinflammation ... -
Three-Dimensional Conductive Scaffolds as Neural Prostheses Based on Carbon Nanotubes and Polypyrrole
Alegret Ramón, Nuria; Domínguez Alfaro, Antonio; González-Domínguez, Jose M.; Arnaiz, Blanca; Cossío Arrieta, Unai; Bosi, Susanna; Vázquez, Ester; Ramos Cabrer, Pedro; Mecerreyes Molero, David; Prato, Maurizio (ACS Publications, 2018-12-19)Three-dimensional scaffolds for cellular organization need to enjoy a series of specific properties. On the one hand, the morphology, shape and porosity are critical parameters and eventually related with the mechanical ...