BackBrowsing Artículos by Author "Esteller, Manel"
Now showing items 1-4 of 4
-
A new approach to epigenome-wide discovery of non-invasive methylation biomarkers for colorectal cancer screening in circulating cell-free DNA using pooled samples
Gallardo-Gómez, María; Moran, Sebastian; Páez de la Cadena, María; Martínez-Zorzano, Vicenta Soledad; Rodríguez-Berrocal, Francisco Javier; Rodríguez-Girondo, Mar; Esteller, Manel; Cubiella, Joaquín; Bujanda Fernández de Pierola, Luis
; Castells, Antoni; Balaguer, Francesc; Jover, Rodrigo; De Chiara, Loretta (Biomed Central, 2018-04-16)
Background: Colorectal cancer is the fourth cause of cancer-related deaths worldwide, though detection at early stages associates with good prognosis. Thus, there is a clear demand for novel non-invasive tests for the early ... -
Lymphangioleiomyomatosis Biomarkers Linked to Lung Metastatic Potential and Cell Stemness
Ruiz de Garibay, Gorka; Herranz, Carmen; Llorente, Alicia; Boni, Jacopo; Serra- Musach, Jordi; Mateo, Francesca; Aguilar, Helena; Gómez-Baldó, Laia; Petit, Anna; Vidal, August; Climent, Fina; Hernández-Losa, Javier; Cordero, Álex; González- Suárez, Eva; Sánchez-Mut, José Vicente; Esteller, Manel; Llatjós, Roger; Varela, Mar; López Fernández de Villaverde, José Ignacio; García, Nadia; Extremera, Ana I.; Gumà, Anna; Ortega, Raúl; Plà, María Jesús; Fernández, Adela; Pernas, Sònia; Falo, Catalina; Morilla, Idoia; Campos, Miriam; Gil, Miguel; Román, Antonio; Molina-Molina, María; Ussetti, Piedad; Laporta, Rosalía; Valenzuela, Claudia; Ancochea, Julio; Xaubet, Antoni; Casanova, Álvaro; Pujana, Miguel Angel (Public Library Science, 2015-07-07)
Lymphangioleiomyomatosis (LAM) is a rare lung-metastasizing neoplasm caused by the proliferation of smooth muscle-like cells that commonly carry loss-of-function mutations in either the tuberous sclerosis complex 1 or 2 ... -
Synthetic Conjugates of Ursodeoxycholic Acid Inhibit Cystogenesis in Experimental Models of Polycystic Liver Disease
Caballero Camino, Francisco Javier; Rivilla de la Cruz, Iván ; Herráez Aguilar, Elisa; Briz Sánchez, Oscar; Santos Laso, Álvaro; ; ; Rodrigues, Pedro M.; Muñoz Garrido, Patricia; Jin, Sujeong; Peixoto, Estanislao; Richard, Seth; Gradilone, Sergio A.; Perugorria Montiel, María Jesús; Esteller, Manel; Bujanda Fernández de Pierola, Luis ; Marin, José J. G.; Bañales Asurmendi, Jesús María ; Cossío Mora, Fernando Pedro (Wiley, 2020-09-22)
Background and Aims Polycystic liver diseases (PLDs) are genetic disorders characterized by progressive development of symptomatic biliary cysts. Current surgical and pharmacological approaches are ineffective, and liver ... -
Towards a more precise therapy in cancer: Exploring epigenetic complexity
Cossío Mora, Fernando Pedro; Esteller, Manel; Berdasco, María (Elsevier, 2020-08)
A plethora of preclinical evidences suggests that pharmacological targeting of epigenetic dysregulation is a potent strategy to combat human diseases. Nevertheless, the implementation of epidrugs in clinical practice is ...