Browsing Artículos by Author "Gerovska, Daniela"
Now showing items 1-6 of 6
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An Integrative Omics Approach Reveals Involvement of BRCA1 in Hepatic Metastatic Progression of Colorectal Cancer
Gerovska, Daniela; Larrinaga Embeita, Gorka ; Solano Iturri, Jon Danel; Márquez Clavijo, Joana ; García Gallastegui, Patricia ; Khatib, Abdel Majid; Poschmann, Gereon; Stühler, Kai; Armesto, María; Lawrie, Charles; Badiola Echaburu, Iker ; Araúzo Bravo, Marcos J. (MDPI, 2020-08-22)(1) Background & Aims: The roles of different cells in the tumor microenvironment (TME) are critical to the metastatic process. The phenotypic transformation of the liver cells is one of the most important stages of the ... -
GeromiRs Are Downregulated in the Tumor Microenvironment during Colon Cancer Colonization of the Liver in a Murine Metastasis Model
Gerovska, Daniela; García Gallastegui, Patricia ; Crende Arruabarrena, Olatz ; Márquez Clavijo, Joana ; Larrinaga Embeita, Gorka ; Unzurrunzaga, Maite; Araúzo Bravo, Marcos J.; Badiola Echaburu, Iker (MDPI, 2021-05-01)Cancer is a phenomenon broadly related to ageing in various ways such as cell cycle deregulation, metabolic defects or telomerases dysfunction as principal processes. Although the tumor cell is the main actor in cancer ... -
HuR/ELAVL1 drives malignant peripheral nerve sheath tumor growth and metastasis
Palomo Irigoyen, Marta; Pérez Andrés, Encarni; Iruarrizaga Lejarreta, Marta; Barreira Manrique, Adrián; Tamayo Caro, Miguel; Vila Vecilla, Laura; Moreno Cugnon, Leire; Beitia, Nagore; Medrano, Daniela; Fernández Ramos, David; Lozano, Juan José; Okawa, Satoshi; Lavín, José L.; Martín Martín, Natalia; Sutherland, James D.; Guitiérez de Juan, Virginia; González López, Monika; Macías Cámara, Nuria; Mosén Ansorena, David; Laraba, Liyam; Hanemann, C. Oliver; Ercolano, Emanuela; Parkinson, David B.; Schultz, Christopher W.; Araúzo Bravo, Marcos J.; Ascensión, Alex M.; Gerovska, Daniela; Iribar López, Haizea; Izeta Permisán, Ander ; Pytel, Peter; Krastel, Philipp; Provenzani, Alessandro; Seneci, Pierfausto; Carrasco, Ruben D.; Del Sol, Antonio; Martínez Chantar, María Luz ; Barrio Olano, María Rosa; Serra, Eduard; Lazaro, Conxi; Flanagan, Adrienne M.; Gorospe, Myriam; Ratner, Nancy; Aransay Bañares, Ana María; Carracedo Pérez, Arkaitz ; Varela Rey, Marta; Woodhoo, Ashwin (The American Society for Clinical Investigation, 2020-07-01)Cancer cells can develop a strong addiction to discrete molecular regulators, which control the aberrant gene expression programs that drive and maintain the cancer phenotype. Here, we report the identification of the ... -
PR-LncRNA Signature Regulates Glioma Cell Activity Through Expression of SOX Factors
Torres Bayona, Sergio Andrés; Aldaz Donamaría, Paula; Auzmendi Iriarte, Jaione; Sáenz Antoñanzas, Ander; García Camino, Idoia; Arrazola Schlamilch, Mariano; Gerovska, Daniela; Undabeitia Huertas, José; Querejeta Ayerra, Arrate; Egaña Otaño, Larraitz; Villanua Bernues, Jorge Alberto; Ruiz Díaz, Irune ; Sarasqueta Eizaguirre, Cristina; Urculo Bareño, Enrique; Araúzo Bravo, Marcos J.; Huarte Martínez, Maite; Samprón Lebed, Nicolás; Matheu Fernández, Ander (Nature Publishing Group, 2018-08-24)Long non-coding RNAs (LncRNAs) have emerged as a relevant class of genome regulators involved in a broad range of biological processes and with important roles in tumor initiation and malignant progression. We have previously ... -
Reiterative Infusions of MSCs Improve Pediatric Osteogenesis Imperfecta Eliciting a Pro-Osteogenic Paracrine Response: TERCELOI Clinical Trial
Infante, Arantza; Gener, Blanca; Vázquez Ronco, Miguel; Olivares, Nerea; Arrieta, Arantza; Grau, Gema; Llano Rivas, Isabel; Madero, Luis; Bueno, Ana María; Sagastizabal, Belén; Gerovska, Daniela; Araúzo Bravo, Marcos J.; Astigarraga Aguirre, María Iciar; Rodríguez López, Clara Isabel (John Wiley & Sons, 2021-01-13)Background Osteogenesis imperfecta (OI) is a rare genetic disease characterized by bone fragility, with a wide range in the severity of clinical manifestations. The majority of cases are due to mutations in the COL1A1 or ... -
Reiterative infusions of MSCs improve pediatric osteogenesis imperfecta eliciting a pro-osteogenic paracrine response: TERCELOI clinical trial
Infante, Arantza; Gener, Blanca; Vázquez, Miguel; Olivares, Nerea; Arrieta, Arantza; Grau, Gema; Llano, Isabel; Madero, Luis; Bueno, Ana Maria; Sagastizabal, Belén; Gerovska, Daniela; Araúzo Bravo, Marcos J.; Astigarraga Aguirre, María Iciar; Rodríguez López, Clara Isabel (Wiley, 2021-01-12)Background Osteogenesis imperfecta (OI) is a rare genetic disease characterized by bone fragility, with a wide range in the severity of clinical manifestations. The majority of cases are due to mutations in the COL1A1 or ...