Browsing Artículos by Author "Ghosh, Sankar"

Now showing items 1-2 of 2

    • Thumbnail

      Disease-Associated SNPs in Inflammation-Related lncRNAs 

      Castellanos Rubio, Ainara; Ghosh, Sankar (Frontiers Media, 2019-03-08)
      Immune-mediated diseases, such as celiac disease, type 1 diabetes or multiple sclerosis, are a clinically heterogeneous group of diseases that share many key genetic triggers. Although the pathogenic mechanisms responsible ...
    • Thumbnail

      The T1D-associated lncRNA Lnc13 modulates human pancreatic β cell inflammation by allele-specific stabilization of STAT1 mRNA 

      González Moro, Itziar ORCID; Olazagoitia Garmendia, Ane; Colli, Maikel L.; Cobo Vuilleumier, Nadia; Postler, Thomas S.; Marselli, Lorella; Marchetti, Piero; Ghosh, Sankar; Gauthier, Benoit R.; Eizirik, Decio L.; Castellanos Rubio, Ainara; Santín Gómez, Izortze (National Academy of Sciences, 2020-03-05)
      The vast majority of type 1 diabetes (T1D) genetic association signals lie in non-coding regions of the human genome. Many have been predicted to affect the expression and secondary structure of long non-coding RNAs ...