BackBrowsing Artículos by Author "Lawrie, Charles"
Now showing items 1-4 of 4
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An Integrative Omics Approach Reveals Involvement of BRCA1 in Hepatic Metastatic Progression of Colorectal Cancer
; Larrinaga Embeita, Gorka
; ; Márquez Clavijo, Joana ; García Gallastegui, Patricia ; ; ; ; ; ; Badiola Echaburu, Iker ; (MDPI, 2020-08-22)
(1) Background & Aims: The roles of different cells in the tumor microenvironment (TME) are critical to the metastatic process. The phenotypic transformation of the liver cells is one of the most important stages of the ... -
Expression and activity of angiotensin-regulating enzymes is associated with prognostic outcome in clear cell renal cell carcinoma patients
Errarte Yarza, Peio; Beitia San Vicente, Maider; Pérez Urzelai, Itxaro; Manterola, Lorea; Lawrie, Charles; Solano Iturri, Jon Danel; Calvete Candenas, Julio; Unda Urzaiz, Jesús Miguel; López, José I.; Larrinaga Embeita, Gorka (Public Library Science, 2017-08-15)
The discovery of the intrarenal renin-angiotensin system (iRAS), which regulates angiogenesis, cell differentiation and proliferation, has opened new perspectives in the knowledge of kidney carcinogenesis. In this study ... -
Ideafix: a decision tree-based method for the refinement of variants in FFPE DNA sequencing data
Tellaetxe Abete, Maitena; Calvo Molinos, Borja; Lawrie, Charles (Oxford University Press, 2021-12)
[EN]Increasingly, treatment decisions for cancer patients are being made from next-generation sequencing results generated from formalin-fixed and paraffin-embedded (FFPE) biopsies. However, this material is prone to ... -
Stromal oncostatin M cytokine promotes breast cancer progression by reprogramming the tumor microenvironment
Araujo, Angela M.; Abaurrea, Andrea; Azcoaga, Peio; López Velazco, Joanna I.; Manzano, Sara; Rodríguez Martínez, Javier; Rezola, Ricardo; Egia Mendikute, Leire; Valdés Mora, Fátima; Flores, Juana M.; Jenkins, Liam; Pulido, Laura; Osorio Querejeta, Iñaki; Fernández Nogueira, Patricia; Ferrari, Nicola; Viera, Cristina; Martín Martín, Natalia; Tzankov, Alexandar; Eppenberger Castori, Serenella; Álvarez López, Isabel; Urruticoechea, Ander; Bragado, Paloma; Coleman, Nicholas; Palazón, Asís; Carracedo Pérez, Arkaitz; Gallego Ortega, David; Calvo González, Fernando; Isacke, Clare M.; Caffarel, María M.; Lawrie, Charles (American Society of Clinical Investigation, 2022-04-01)
[EN] The tumor microenvironment (TME) is reprogrammed by cancer cells and participates in all stages of tumor progression. The contribution of stromal cells to the reprogramming of the TME is not well understood. Here, we ...