Listar Artículos por autor "Lawrie, Charles H."
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High SOX9 Maintains Glioma Stem Cell Activity through a Regulatory Loop Involving STAT3 and PML
Aldaz Donamaría, Paula; Martín Martín, Natalia; Sáenz Antoñanzas, Ander; Carrasco-Garcia, Estefania; Álvarez-Satta, María; Elúa Pinin, Alejandro; Pollard, Steven M.; Lawrie, Charles H.; Moreno-Valladares, Manuel; Samprón Lebed, Nicolás; Hench, Jürgen; Lovell-Badge, Robin; Carracedo Pérez, Arkaitz; Matheu Fernández, Ander (MDPI, 2022-05)
Glioma stem cells (GSCs) are critical targets for glioma therapy. SOX9 is a transcription factor with critical roles during neurodevelopment, particularly within neural stem cells. Previous studies showed that high levels ... -
Identification of miRNAs and Their Target Genes Associated with Sunitinib Resistance in Clear Cell Renal Cell Carcinoma Patients
Armesto, María; Nemours, Stéphane; Arestín, María; Bernal, Iraide; Solano Iturri, Jon Danel; Manrique, Manuel; Basterretxea, Laura; Larrinaga Embeita, Gorka; Angulo, Javier C.; Lecumberri, David; Iturregui, Ane Miren; López, José I.; Lawrie, Charles H. (MDPI, 2024-06-22)
Sunitinib has greatly improved the survival of clear cell renal cell carcinoma (ccRCC) patients in recent years. However, 20–30% of treated patients do not respond. To identify miRNAs and genes associated with a response, ...