Browsing Artículos by Author "Ocejo Vinyals, Javier Gonzalo"
Now showing items 1-2 of 2
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First computational design using lambda-superstrings and in vivo validation of SARS-CoV-2 vaccine
Martínez Fernández, Luis ; Malaina Celada, Iker ; Salcines Cuevas, David; Terán Navarro, Héctor; Zeoli, Andrea; Alonso Alegre, Santos ; Martínez de la Fuente Martínez, Ildefonso Abel; González López, Elena; Ocejo Vinyals, Javier Gonzalo; Gozalo Margüello, Mónica; Calvo Montes, Jorge; Álvarez Domínguez, Carmen (Nature Research, 2022-04)[EN] Coronavirus disease 2019 (COVID-19) is the greatest threat to global health at the present time, and considerable public and private effort is being devoted to fighting this recently emerged disease. Despite the ... -
Testing a vaccine candidate against Hepatitis C virus designed by combinatorial optimization
Malaina Celada, Iker ; Martínez Fernández, Luis ; Salcines Cuevas, David; Terán Navarro, Héctor; Ocejo Vinyals, Javier Gonzalo; González López, Elena; Soriano, Vicente; Ubeda, María; Pérez Pinilla, Martín Blas ; Martínez de la Fuente Martínez, Ildefonso Abel; Álvarez Domínguez, Carmen (Nature, 2023)This paper presents a new procedure for vaccine design against highly variable viruses such as Hepatitis C. The procedure uses an optimization algorithm to design vaccines that maximize the coverage of epitopes across ...