Browsing Artículos by Author "Wang, Demin"

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      Altered nuclear export signal recognition as a driver of oncogenesis 

      Taylor, Justin; Sendino Mouliet, Maria ORCID; Gorelick, Alexander N; Pastore, Alessandero; Chang, Matthew T.; Penson, Alexander V.; Gavrila, Elena I.; Stewart, Connor; Melnik, Ella M.; Herrejon Chavez, Florisela; Bitner, Lilian; Yoshimi, Akihide; Lee, Stanley Chun-wei; Inoue, Daichi; Liu, Bo; Zhang, Xiao J.; Mato, Anthony R.; Dogan, Ahmet; Kharas, Michael G.; Chen, Yuhong; Wang, Demin; Soni, Rajesh K.; Hendrickson, Ronald C.; Prieto Agujeta, Gorka ORCID; Rodríguez Pérez, José Antonio ORCID; Taylor, Barry S.; Abdel-Wahab, Omar (AACR, 2019-10-01)
      Altered expression of XPO1, the main nuclear export receptor in eukaryotic cells, has been observed in cancer, and XPO1 has been a focus of anticancer drug development. However, mechanistic evidence for cancer-specific ...