Browsing Artículos by Author "Wang, Qian"
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Advances in the Development of Trifluoromethoxylation Reagents
Wang, Qian; Zhang, Xin; Sorochinsky, Alexander E.; Butler, Greg; Han, Jianlin; Soloshonok, Vadym Anatolievch
(MDPI, 2021-12-10)
This review provides a short summary of the traditional methods for synthesis of CF3-O-containing compounds, followed by a critical overview of known trifluoromethoxylating reagents, focusing on their preparation, synthetic ... -
The Latest FDA-Approved Pharmaceuticals Containing Fragments of Tailor-Made Amino Acids and Fluorine
Wang, Qian; Han, Jianlin; Sorochinsky, Alexander
; Landa Álvarez, Aitor; Butler, Greg; Soloshonok, Vadym Anatolievch
(MDPI, 2022-08-14)
Nowadays, the selective introduction of fluorine into bioactive compounds is a mature strategy in the design of drugs allowing to increase efficiency, biological half-life and bio-absorption. On the other hand, amino acids ...