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      Immunogenomics of Colorectal Cancer Response to Checkpoint Blockade: Analysis of the KEYNOTE 177 Trial and Validation Cohorts 

      Bortolomeazzi, Michele; Keddar, Mohamed Reda; Montorsi, Lucia; Acha-Sagredo, Amelia; Benedetti, Lorena; Temelkovski, Damjan; Choi, Subin; Petrov, Nedyalko; Todd, Katrina; Wai, Patty; Kohl, Johannes; Denner, Tamara; Nye, Emma; Goldstone, Robert; Ward, Sophia; Wilson, Gareth A.; Al Bakir, Maise; Swanton, Charles; John, Susan; Miles, James; Larijani, Banafshé; Kunene, Victoria; Fontana, Elisa; Arkenau, Hendrik-Tobias; Parker, Peter J.; Rodriguez-Justo, Manuel; Shiu, Kai-Keen; Spencer, Jo; Ciccarelli, Francesca D. (Elsevier, 2021-10)
      BACKGROUND & AIMS: Colorectal cancer (CRC) shows variable response to immune checkpoint blockade, which can only partially be explained by high tumor mutational burden (TMB). We conducted an integrated study of the cancer ...