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Intrapericardial Delivery of APA-Microcapsules as Promising Stem Cell Therapy Carriers in an Experimental Acute Myocardial Infarction Model
(MDPI, 2021-11-01)
The administration of cardiosphere-derived cells (CDCs) after acute myocardial infarction (AMI) is very promising. CDC encapsulation in alginate-poly-l-lysine-alginate (APA) could increase cell survival and adherence. The ...
Meta-Analysis of Prevalence of Depression in Dental Students during COVID-19 Pandemic
(MDPI, 2021-11-21)
Background and Objectives: The COVID-19 pandemic has a negative impact on the mental health of the population in general, and in college students in particular. Dental students have seen their teaching altered and their ...
Hybrid Quinolinyl Phosphonates as Heterocyclic Carboxylate Isosteres: Synthesis and Biological Evaluation against Topoisomerase 1B (TOP1B)
(MDPI, 2021-08-09)
This work describes, for the first time, the synthesis of dialkyl (2-arylquinolin-8-yl)phosphonate derivatives. The preparation was carried out through a direct and simple process as a multicomponent Povarov reaction of ...
A Multicomponent Protocol for the Synthesis of Highly Functionalized γ-Lactam Derivatives and Their Applications as Antiproliferative Agents
(MDPI, 2021-08-09)
An efficient synthetic methodology for the preparation of 3-amino 1,5-dihydro-2H-pyrrol-2-ones through a multicomponent reaction of amines, aldehydes, and pyruvate derivatives is reported. In addition, the densely substituted ...
Simple and Fast DNA Based Sensor System for Screening of Small-Molecule Compounds Targeting Eukaryotic Topoisomerase 1
(MDPI, 2021-08-13)
Background: Eukaryotic topoisomerase 1 is a potential target of anti-parasitic and anti-cancer drugs. Parasites require topoisomerase 1 activity for survival and, consequently, compounds that inhibit topoisomerase 1 activity ...
Co-Creation of Knowledge for Ecosystem Services Approach to Spatial Planning in the Basque Country
(MDPI, 2020-06-30)
Sustainable development has to be based on scientific knowledge, social agreements, and political decisions. This study aimed to analyse the implementation of the ecosystem services approach (ESA) in the spatial planning ...
Floristic Composition Mediates Change in Forage Nutritive Quality of Atlantic Mountain Grasslands after Experimental Grazing Exclusion
(MDPI, 2020-12-24)
Simultaneous reduction of biodiversity and forage nutritive value after grazing abandonment represents a critical agroecological problem observed in temperate mountain grasslands. However, how both processes affect each ...
Searching for kagome multi-bands and edge states in a predicted organic topological insulator
(Royal Society of Chemistry, 2021-03-18)
Recently, mixed honeycomb-kagome lattices featuring metal-organic networks have been theoretically proposed as topological insulator materials capable of hosting nontrivial edge states. This new family of so-called "organic ...
Functionally Graded AISI 316L and AISI H13 Manufactured by L-DED for Die and Mould Applications
(MDPI, 2021-01-15)
Tooling in the die and mould industry is subjected to high-wear and high-temperature environments, which often leads to the premature failure of this high-added-value tooling. When severe damage occurs, an alternative to ...
Social Dominance Orientation Boosts Collective Action Among Low-Status Groups
(Frontiers Media, 2021-06-11)
We propose that low-status group members' support for group-based hierarchy and inequality (i.e., social dominance orientation; SDO) may represent an ideological strategy to guarantee the legitimacy of future ingroup ...