Search
Now showing items 11-18 of 18
In Vitro Interaction and Killing-Kinetics of Amphotericin B Combined with Anidulafungin or Caspofungin against Candida auris
(MDPI, 2021-08-25)
Treatment of invasive infections caused by Candida auris is challenging due to the limited therapeutic options. The combination of antifungal drugs may be an interesting and feasible approach to be investigated. The aim ...
In Vitro Synergistic Interactions of Isavuconazole and Echinocandins against Candida auris
(MDPI, 2021-03-28)
Candida auris is an emergent fungal pathogen that causes severe infectious outbreaks globally. The public health concern when dealing with this pathogen is mainly due to reduced susceptibility to current antifungal drugs. ...
In Vitro Antifungal Activity of Ibrexafungerp (SCY-078) Against Contemporary Blood Isolates From Medically Relevant Species of Candida: A European Study
(Frontiers Media, 2022-05)
BackgroundIbrexafungerp (SCY-078) is the newest oral and intravenous antifungal drug with broad activity, currently undergoing clinical trials for invasive candidiasis. ObjectiveThe aim of this study was to assess the in ...
Candidiasis by Candida glabrata, Candida nivariensis and Candida bracarensis in Galleria mellonella: Virulence and Therapeutic Responses to Echinocandins
(MDPI, 2021-11-23)
Candida albicans is the major etiological agent of invasive candidiasis but the increasing prevalence of emerging species of Candida, such as Candida glabrata and phylogenetically closely related species, Candida nivariensis ...
In vitro activities of carvacrol, cinnamaldehyde and thymol against Candida biofilms
(Elsevier, 2021-11)
[EN]Oral candidiasis is frequently associated with Candida biofilms. Biofilms are microbial communities related to persistent, recalcitrant and difficult to-treat infections. Conventional treatments are not sufficient to ...
Caenorhabditis elegans as a Model System To Assess Candida glabrata, Candida nivariensis, and Candida bracarensis Virulence and Antifungal Efficacy
(American Society for Microbiology (ASM), 2020-09-21)
Although Candida albicans remains the major etiological agent of invasive
candidiasis, Candida glabrata and other emerging species of Candida are
increasingly isolated. This species is the second most prevalent cause of ...
Utility of two PCR-RFLP-based techniques for identification of Candida parapsilosis complex blood isolates
(Wiley-Blackwell, 2020-05)
Background: Candida parapsilosis is the second or third most frequently isolated
Candida species related to nosocomial infections, even overtaking Candida albicans
in some hospitals. C. parapsilosis constitutes a complex ...
PK/PD modeling and simulation of the in vitro activity of the combinations of isavuconazole with echinocandins against Candida auris
(Wiley, 2023-06)
In vitro combination of echinocandins and isavuconazole against the emerging species Candida auris is mainly synergistic. However, this combination has not been evaluated in clinical settings. A pharmacokinetic/pharmacodynamic ...