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Now showing items 5721-5730 of 5750
Revealing novel biomarkers for diagnosing chronic kidney disease in pediatric patients
(Nature, 2024)
Pediatric chronic kidney disease (CKD) is a clinical condition characterized by progressive renal function deterioration. CKD diagnosis is based on glomerular filtration rate, but its reliability is limited, especially at ...
Linked evolution of Paleocene sea floor relief and deep marine currents in the Subbetic Zone, southern Spain
(Elsevier, 2024-06)
Paleocene deposits of the Subbetic Zone (southern Spain) provide outstanding evidence of the influence of sea mountains on deep marine currents. This part of the Betic Cordillera External Zones corresponds to the distal ...
Controlling of the single domain wall propagation in magnetic microwires by magnetostatic interaction
(Elsevier, 2024-06)
Ultrafast magnetization switching through the single domain wall (DW) propagation has been reported in amorphous micrometric and submicrometric wires. However the performance of prospective devices utilizing DW propagation ...
Applying the Kolmogorov–Zurbenko filter followed by random forest models to 7Be observations in Spain (2006–2021)
(Elsevier, 2024-05)
n this study, we analysed 7Be weekly surface measurements from six Spanish laboratories from 2006 to 2021. The Kolmogorov–Zurbenko filter was applied to the six 7Be time series, and following an iterative process, the ...
Rigidified Bis(sulfonyl)ethylenes as Effective Michael Acceptors for Asymmetric Catalysis: Application to the Enantioselective Synthesis of Quaternary Hydantoins
(ACS, 2023-01-11)
The catalytic, enantio- and diastereoselective addition of
hydantoin surrogates II to “rigidified” vinylidene bis(sulfone) reagents is
developed, thus overcoming the inability of commonly employed β-
substituted vinylic ...
Brønsted Base-Catalyzed Enantioselective α-Functionalization of Carbonyl Compounds Involving π-Extended Enolates
(Wiley, 2023-11)
Chiral Brønsted base (BB) catalyzed asymmetric transformations constitute an important tool for synthesis. A meaningful fraction of these transformations proceeds through transiently generated enolate intermediates, which ...
Catalytic Asymmetric α-Functionalization of α-Branched Aldehydes
(MDPI, 2023-03-16)
Aldehydes constitute a main class of organic compounds widely applied in synthesis. As such, catalyst-controlled enantioselective α-functionalization of aldehydes has attracted great interest over the years. In this context, ...
Reducing Negative Aging Stereotypes via Educational Intervention in Older People: A Randomized Controlled Study
(Sage, 2022-09-13)
Anti-ageism interventions traditionally target younger individuals. We analyzed the effect of an educational intervention that combined an infusion of aging content with videos to reduce negative stereotypes toward aging ...
Organocatalytic Michael Addition of Unactivated α-Branched Nitroalkanes to Afford Optically Active Tertiary Nitrocompounds
(ACS, 2023-11-27)
The direct, asymmetric conjugate addition of unactivated α-branched nitroalkanes is developed based on the combined use of chiral amine/ureidoaminal bifunctional catalysts and a tunable acrylate template to provide tertiary ...
Synthesis of 4,6-Difluoro-Tryptophan as a Probe for Protein 19F NMR
(Wiley-VCH GmbH, Weinheim, 2024-03-25)
A scalable procedure for the synthesis of 4,6-difluorotryptophan is reported based on a deaminative
coupling of a 4,6-difluorogramine with 2-benzylthio-1,5-dihydro-4H-imidazolone as glycine equivalent. Thus prepared ...