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Integrative genomic analyses reveal mechanisms of glucocorticoid resistance in acute lymphoblastic leukemia
(Springer Nature, 2020-03)
Identification of genomic and epigenomic determinants of drug resistance provides important insights for improving cancer treatment. Using agnostic genome-wide interrogation of mRNA and miRNA expression, DNA methylation, ...
Conjugative Coupling Proteins and the Role of Their Domains in Conjugation, Secondary Structure and in vivo Subcellular Location
(Frontiers Media, 2020-08-11)
Type IV Coupling Proteins (T4CPs) are essential elements in many type IV secretion systems (T4SSs). The members of this family display sequence, length, and domain architecture heterogeneity, being the conserved ...
Submerged and reused: An archaeometric approach to the early Modern ceramics from Aveiro (Portugal)
(2020-11-02)
Aveiro, a city located in northern Portugal that lies next to the Atlantic Ocean, has a long potting tradition.
Indeed, during the 15th–17th centuries, this region played an important role in the maritime trade between ...
Promoting adherence to psychopharmacological treatment among prisoners with mental health problems: Follow-up of a randomized controlled trial
(Elsevier, 2020-12-14)
This study presents follow-up results regarding a treatment adherence programme (TAP) for prisoners, the initial effectiveness of which we previously evaluated in a randomized controlled trial. Here we used an experimental ...
Strategies to Improve Hazardous Waste Management at the Faculty of Engineering Vitoria-Gasteiz UPV/EHU
(2020-10-01)
[EN] Universities, considered as agents of social change, are essential for providing knowledge, innovations and solutions to the community, in order to nurture future leaders towards sustainable development. Therefore, ...
The Emotional Divergent–Convergent Thinking Program (EDICOP): Design, Implementation, and Results
(MDPI, 2020-11-13)
In a social environment that requires young people to adapt to increasingly demanding situations, emotional education and creativity training may be key for both personal development and academic performance. Given that ...
Age‐related cognitive decline in myotonic dystrophy type 1: An 11‐year longitudinal follow‐up study
(Wiley, 2020-03)
Background Myotonic dystrophy type 1 (DM1) is an inherited multi-systemic disease involving the central nervous system (CNS) and is consequently characterized by a range of cognitive impairments. However, whether this ...
The Sailor diagram – A new diagram for the verification of two-dimensional vector data from multiple models
(Copernicus Gesellschaft, 2020-07-15)
A new diagram is proposed for the verification of vector quantities generated by multiple models against a set of observations. It has been designed with the objective, as in the Taylor diagram, of providing a visual ...
Problem-Based Learning in University Studies on Renewable Energies: Case of a Laboratory Windpump
(MDPI, 2020-03-23)
In the last eight years, the new faculty of Engineering in Renewable Energies at the University of the Basque Country in Eibar has developed several sustainability goals related to clean energy and climate change, but also ...
The Binding of Aβ42 Peptide Monomers to Sphingomyelin/Cholesterol/Ganglioside Bilayers Assayed by Density Gradient Ultracentrifugation
(MDPI, 2020-02-29)
The binding of Aβ42 peptide monomers to sphingomyelin/cholesterol (1:1 mol ratio) bilayers containing 5 mol% gangliosides (either GM1, or GT1b, or a mixture of brain gangliosides) has been assayed by density gradient ...