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PI3K-regulated Glycine N-methyltransferase is required for the development of prostate cancer
(Springer Nature, 2022-02)
[EN] Glycine N-Methyltransferase (GNMT) is a metabolic enzyme that integrates metabolism and epigenetic regulation. The product of GNMT, sarcosine, has been proposed as a prostate cancer biomarker. This enzyme is predominantly ...
Birth and Early Steps of the Organization of Biophysics in Spain
(MDPI, 2022-11-19)
In the 1960s, Biophysics was an unheard of scientific field in Spain, and even outside Spain, the distinction between Biophysics and Molecular Biology was not clear at the time. This paper describes briefly the developments ...
Relationship between the Dynamics of Gross Composition, Free Fatty Acids and Biogenic Amines, and Microbial Shifts during the Ripening of Raw Ewe Milk-Derived Idiazabal Cheese
(MDPI, 2022-11-21)
This study reports for the first time the relationship between bacterial succession, characterized by high-throughput sequencing (sequencing of V3–V4 16S rRNA regions), and the evolution of gross composition, free fatty ...
Quantitative super-resolution imaging of pathological aggregates reveals distinct toxicity profiles in different synucleinopathies
(National Academy of Sciences, 2022-10)
Protein aggregation is a hallmark of major neurodegenerative disorders. Increasing data suggest that smaller aggregates cause higher toxic response than filamentous aggregates (fibrils). However, the size of small aggregates ...
Characterization of Microbial Shifts during the Production and Ripening of Raw Ewe Milk-Derived Idiazabal Cheese by High-Throughput Sequencing
(MDPI, 2022-05-18)
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Characterization of Microbial Shifts during the Production and Ripening of Raw Ewe Milk-Derived Idiazabal Cheese by High-Throughput Sequencing
by Gorka Santamarina-García
* [ORCID] ...
Dietary fatty acid metabolism: New insights into the similarities of lipid metabolism in humans and hamsters
(Elsevier, 2022-07)
[EN] Hamsters have been long accepted as animal models to study the lipid metabolism in humans. However, very few scientific works described in detail the fatty acid (FA) composition of plasma and erythrocytes in hamsters ...
Antibiotics in Dairy Production: Where Is the Problem?
(MDPI, 2022-08-01)
Antibiotics have long been used for the prevention and treatment of common diseases and for prophylactic purposes in dairy animals. However, in recent decades it has become a matter of concern due to the widespread belief ...
Reply to Roy and Pucadyil: A gain of function by a GTPase-impaired Drp1
(National Academy of Sciences, 2022-06)
Identification of a New Cholesterol-Binding Site within the IFN-gamma Receptor that is Required for Signal Transduction
(Wiley, 2022)
[EN] The cytokine interferon-gamma (IFN-gamma) is a master regulator of innate and adaptive immunity involved in a broad array of human diseases that range from atherosclerosis to cancer. IFN-gamma exerts it signaling ...
Super-Resolution Microscopy to Study Interorganelle Contact Sites
(MDPI, 2022-12-05)
Interorganelle membrane contact sites (MCS) are areas of close vicinity between the membranes of two organelles that are maintained by protein tethers. Recently, a significant research effort has been made to study MCS, ...