Search
Now showing items 111-116 of 116
Association between birthweight and later body mass index: an individual-based pooled analysis of 27 twin cohorts participating in the CODATwins project
(Oxford University Press, 2017-10)
Background: There is evidence that birthweight is positively associated with body mass
index (BMI) in later life, but it remains unclear whether this is explained by genetic factors
or the intrauterine environment. We ...
Genetic and environmental factors affecting birth size variation: a pooled individual-based analysis of secular trends and global geographical differences using 26 twin cohorts
(Oxford University Press, 2018-05-19)
Background: The genetic architecture of birth size may differ geographically and over
time. We examined differences in the genetic and environmental contributions to birthweight,
length and ponderal index (PI) across ...
Genetic and environmental influences on adult human height across birth cohorts from 1886 to 1994
(eLife Sciences Publications, 2016-12-14)
Human height variation is determined by genetic and environmental factors, but it
remains unclear whether their influences differ across birth-year cohorts. We conducted an
individual-based pooled analysis of 40 twin ...
A novel RT-QPCR-based assay for the relative quantification of residue specific m6A RNA methylation
(Nature Publishing Group, 2019-12)
N6-methyladenosine (m6A) is the most common and abundant RNA modification. Recent studies have shown its importance in the regulation of several biological processes, including the immune response, and different approaches ...
The methylome of the celiac intestinal epithelium harbours genotype-independent alterations in the HLA region
(Nature Publishing, 2019-02-04)
The Human Leucocyte Antigen (HLA) locus and other DNA sequence variants identified in Genome-Wide Association (GWA) studies explain around 50% of the heritability of celiac disease (CD). However, the pathogenesis of CD ...
Genetic and environmental influences on height from infancy to early adulthood: An individualbased pooled analysis of 45 twin cohorts
(Nature Research, 2016-06-23)
Height variation is known to be determined by both genetic and environmental factors, but a
systematic description of how their influences differ by sex, age and global regions is lacking. We
conducted an individual-based ...