Search
Now showing items 2901-2910 of 2942
MTHFR Polymorphisms In Childhood Acute lymphoblastic Leukemia: Influence On Methotrexate Therapy
(Dove Medical Press LTD, 2017)
Methotrexate (MTX) is an important component in the therapy used to treat childhood
acute lymphoblastic leukemia (ALL). Methylenetetrahydrofolate reductase (MTHFR) is a key
enzyme for MTX pharmacokinetics. Two single-nucleotide ...
Confirmation of involvement of new variants at CDKN2A/B in pediatric acute lymphoblastic leukemia susceptibility in the Spanish population
(Public Library Science, 2017-05-08)
The locus CDKN2A/B (9p21.3), which comprises the tumor suppressors genes CDKN2A and CDKN2B and the long noncoding RNA (lncRNA) known as ANRIL (or CDKN2B-AS), was associated with childhood acute lymphoblastic leukemia (ALL) ...
Involvement of SNPs in miR-3117 and miR-3689d2 in Childhood Acute Lymphoblastic Leukemia Risk
(Board, 2018-04-01)
Acute lymphoblastic leukemia (ALL) is the most common cancer in children. Numerous studies have shown that microRNAs (miRNAs) could play a role in this disease. Nowadays, more than 2500 miRNAs have been described, that ...
The use of role-play games in teaching: The International Climate Negotiation Game
(2016-04-13)
This paper presents a role-play game designed by the authors, which focuses on
international climate negotiations. The game has been used at a university with students all
drawn from the same course and at summer schools ...
ADAPTECC: A Role-Play Game about Adapting to Climate Change
(2016-04-19)
The ADAPTECC Climate Change Adaptation Game is a role-play game designed to enable
players to experience the difficulties that arise at local and regional levels when authorities have
to implement adaptation measures. ...
Genetic and metabolic determinants of methotrexate-induced mucositis in pediatric acute lymphoblastic leukemia
(Springer Nature, 2014-11-04)
Methotrexate (MTX) is an effective and toxic chemotherapeutic drug in the treatment of pediatric acute lymphoblastic leukemia(ALL). In this prospective study, we aimed to identify metabolic and genetic determinants of MTX ...
Stability of a Rh/CeO2–ZrO2 Catalyst in the Oxidative Steam Reforming of Raw Bio-oil
(ACS, 2018-02-21)
The oxidative steam reforming (OSR) of raw bio-oil (obtained by fast pyrolysis of pine sawdust) has been studied on a Rh/CeO2-ZrO2 catalyst under a wide range of operating conditions (600-750 ºC; steam to carbon molar ratio ...
Linguistic Accessibility for Small Language Cinema
(IGI Global, 2016)
Audiovisual accessibility is considered as a basic right. In a world where audiovisual material is more and more present, several measures have been taken in order to facilitate the access to it by people living with sensory ...
Velocity and power–load association of bench-press exercise in wheelchair basketball players and their relationships with field-test performance
(Human Kinetics, 2019-07)
Purpose: To analyze the relationship between mean propulsive velocity (MPV) of the bar and relative load (percentage of the 1-repetition maximum [%1RM]) in the bench-press (BP) exercise and to determine the relationship ...