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Super-Resolution STED Microscopy in live Brain Tissue
(Elsevier, 2021-08)
STED microscopy is one of several fluorescence microscopy techniques that permit imaging at higher spatial resolution than what the diffraction-limit of light dictates. STED imaging is unique among these super-resolution ...
Lysophosphatidic Acid Receptor 1 Specifically Labels Seizure-Induced Hippocampal Reactive Neural Stem Cells and Regulates Their Division
(Frontiers Media, 2020-08-14)
A population of neural stem cells (NSCs) dwelling in the dentate gyrus (DG) is able to generate neurons throughout adult life in the hippocampus of most mammals. These NSCs generate also astrocytes naturally and are capable ...
Solid-phase synthesis of imprinted nanoparticles as artificial antibodies against the C-terminus of the cannabinoid CB1 receptor: exploring a viable alternative for bioanalysis
(Springer, 2021-11)
[EN]The production of artificial anti-CB1 antibodies in nanoparticle format is described using the solid-phase imprinting approach. Instead of whole protein imprinting, a linear C-terminus sequence of the receptor comprising ...
Regret and therapeutic decisions in multiple sclerosis care: literature review and research protocol
(Frontiers Media, 2021-06-21)
[EN] Background: Decisions based on erroneous assessments may result in unrealistic
patient and family expectations, suboptimal advice, incorrect treatment, or costlymedical
errors. Regret is a common emotion in daily ...
Genetics of adult attachment: An updated review of the literature
(Baishideng Publishing Group, 2021-09-19)
Attachment style, which has been theorized to be rooted in childhood bonding experiences, influences adult cognitive, emotional and interpersonal functioning. Despite its relationship with early experiences, research ...
Assessment of Psychiatric Symptomatology in Bilingual Psychotic Patients: A Systematic Review and Meta-Analysis
(MDPI, 2020-06-10)
Language plays an important role in psychiatric conditions. Language disturbances are core symptoms of psychiatric ailments, and language is the main diagnostic tool to assess psychopathological severity. Although the ...
Environmental Enrichment Rescues Endocannabinoid-Dependent Synaptic Plasticity Lost in Young Adult Male Mice after Ethanol Exposure during Adolescence
(MDPI, 2021-07-16)
Binge drinking (BD) is a serious health concern in adolescents as high ethanol (EtOH) consumption can have cognitive sequelae later in life. Remarkably, an enriched environment (EE) in adulthood significantly recovers ...
Lack of the transient receptor potential vanilloid 1 shifts cannabinoid-dependent excitatory synaptic plasticity in the dentate gyrus of the mouse brain hippocampus
(Frontiers Media, 2021-07-07)
[EN] The transient receptor potential vanilloid 1 (TRPV1) participates in synaptic functions
in the brain. In the dentate gyrus, post-synaptic TRPV1 in the granule cell (GC)
dendritic spines mediates a type of long-term ...
Contribution of P2X4 Receptors to CNS Function and Pathophysiology
(MDPI, 2020-08-03)
The release and extracellular action of ATP are a widespread mechanism for cell-to-cell communication in living organisms through activation of P2X and P2Y receptors expressed at the cell surface of most tissues, including ...
Role of Mitochondrial Dynamics in Microglial Activation and Metabolic Switch
(American Association Of Immunologists, 2021-08-10)
Microglia act as sensors of injury in the brain, favoring its homeostasis. Their activation and polarization toward a proinflammatory phenotype are associated with injury and disease. These processes are linked to a metabolic ...