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Utility of MALDI-TOF MS as a New Tool for Streptococcus Pneumoniae Serotyping
(Public Library Science, 2019-02-12)
Nowadays, more than 95 different Streptococcus pneumoniae serotypes are known, being less than one third responsible for the majority of severe pneumococcal infections. After the introduction of conjugate vaccines, a change ...
Folding Status Is Determinant over Traffic-Competence in Defining CFTR Interactors in the Endoplasmic Reticulum
(MDPI, 2019-04-14)
The most common cystic fibrosis-causing mutation (F508del, present in ~85% of CF patients) leads to CFTR misfolding, which is recognized by the endoplasmic reticulum (ER) quality control (ERQC), resulting in ER retention ...
Putative Role of Respiratory Muscle Training to Improve Endurance Performance in Hypoxia: A Review
(Frontiers Media, 2019-01-15)
Respiratory/inspiratory muscle training (RMT/IMT) has been proposed to improve the endurance performance of athletes in normoxia. In recent years, due to the increased use of hypoxic training method among athletes, the RMT ...
High-Altitude Cognitive Impairment Is Prevented by Enriched Environment Including Exercise via VEGF Signaling
(Frontiers Media, 2019)
Exposure to hypobaric hypoxia at high altitude (above 2500 m asl) causes cognitive impairment, mostly attributed to changes in brain perfusion and consequently neuronal death. Enriched environment and voluntary exercise ...
Observation of TransverseΛ= ̄ΛHyperon Polarization ine+e−Annihilation at Belle
(American Physical Society, 2019-01-29)
We report the first observation of the spontaneous polarization of Lambda and (Lambda) over bar hyperons transverse to the production plane in e(+)e(-) annihilation, which is attributed to the effect arising from a polarizing ...
Amyotrophic lateral sclerosis: a complex syndrome that needs an integrated research approach
(Wolters Kluwer, 2019-02)
Amyotrophic lateral sclerosis, the most common neurodegenerative disease affecting motor neurons, lacks an effective treatment. A small fraction of amyotrophic lateral sclerosis cases have a familial origin, related to ...
Flexible aromatic disulfide monomers for high-performance self-healable linear and cross-linked poly(urethane-urea) coatings
(Elsevier, 2019)
Implementation of the self-healing concept in coatings is challenging because they have to combine mechanical strength and chain mobility. This challenge is addressed in this work by studying the effect of the polymer ...
Extracellular Vesicles in Liver Diseases: Meeting Report from the International Liver Congress 2018
(Wiley, 2019-02)
Extracellular vesicles (EVs) are small and heterogeneous membrane-bound structures released by cells and found in all biological fluids. They are effective intercellular communicators, acting on a number of close and/or ...
Measurements of Isospin Asymmetry and Difference of Direct CP Asymmetries in Inclusive B→Xsγ Decays
(American Physical Society, 2019-02-20)
We report measurements of isospin asymmetry Delta(0-) and difference of direct CP asymmetries Delta A(CP) between charged and neutral B -> X-s gamma decays. This analysis is based on the data sample containing 772 x 10(6)B ...
Disease-Associated SNPs in Inflammation-Related lncRNAs
(Frontiers Media, 2019-03-08)
Immune-mediated diseases, such as celiac disease, type 1 diabetes or multiple sclerosis, are a clinically heterogeneous group of diseases that share many key genetic triggers. Although the pathogenic mechanisms responsible ...