Search
Now showing items 4521-4530 of 8786
Assessment of Different Niosome Formulations for Optogenetic Applications: Morphological and Electrophysiological Effects
(MDPI, 2023-07-01)
Gene therapy and optogenetics are becoming promising tools for treating several nervous system pathologies. Currently, most of these approaches use viral vectors to transport the genetic material inside the cells, but ...
Age, Origin and Functional Study of the Prevalent LDLR Mutation Causing Familial Hypercholesterolaemia in Gran Canaria
(MDPI, 2023-07-11)
The p.(Tyr400_Phe402del) mutation in the LDL receptor (LDLR) gene is the most frequent cause of familial hypercholesterolaemia (FH) in Gran Canaria. The aim of this study was to determine the age and origin of this prevalent ...
Aerodynamic Performance of Vertical-Axis Wind Turbines
(MDPI, 2023-07-05)
The nonstationary separated incompressible flows around Darrieus and Savonius rotors of vertical-axis wind turbines were investigated through computational simulation using the Reynolds averaged Navier–Stokes equations and ...
Data Mining of Polymer Phase Transitions upon Temperature Changes by Small and Wide-Angle X-ray Scattering Combined with Raman Spectroscopy
(MDPI, 2021-11-30)
The complex physical transformations of polymers upon external thermodynamic changes are related to the molecular length of the polymer and its associated multifaceted energetic balance. The understanding of subtle transitions ...
Preparation of Selenium-Based Drug-Modified Polymeric Ligand-Functionalised Fe3O4 Nanoparticles as Multimodal Drug Carrier and Magnetic Hyperthermia Inductor
(MDPI, 2023-06-30)
In recent years, much effort has been invested into developing multifunctional drug delivery systems to overcome the drawbacks of conventional carriers. Magnetic nanoparticles are not generally used as carriers but can be ...
Normal-Fat vs. High-Fat Diets and Olive Oil vs. CLA-Rich Dairy Fat: A Comparative Study of Their Effects on Atherosclerosis in Male Golden Syrian Hamsters
(MDPI, 2023-07-06)
The relationship between milk fat intake (because of its high saturated fatty acid content) and the risk of suffering from cardiovascular diseases remains controversial. Thus, Golden Syrian hamsters were fed two types of ...
Synthesis of Aminoalkyl Sclareolide Derivatives and Antifungal Activity Studies
(MDPI, 2023-05-12)
Sclareolide was developed as an efficient C-nucleophilic reagent for an asymmetric Mannich addition reaction with a series of N-tert-butylsulfinyl aldimines. The Mannich reaction was carried out under mild conditions, ...
Total and Free Fatty Acids Analysis in Milk and Dairy Fat
(MDPI, 2019-03-05)
Dairy fat is one of the most complex natural fats because of its fatty acid (FA) composition. Ruminant dairy fat contains more than 400 different FA varying in carbon chain length, and degree, position and configuration ...
Predictive Dynamic Window Approach Development with Artificial Neural Fuzzy Inference Improvement
(MDPI, 2019-08-26)
The aim of this paper is to improve the dynamic window approach algorithm for mobile robots by implementing a prediction window with a fuzzy inference system to adapt to fixed parameters, depending on the surrounding ...
Experimental Evaluation of Perfluorocarbon Aerosol Generation with Two Novel Nebulizer Prototypes
(MDPI, 2019-01-05)
The potential of non-invasive ventilation procedures and new minimally invasive techniques has resulted in the research of alternative approaches as the aerosolization for the treatment of respiratory distress syndrome ...