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Now showing items 8311-8320 of 8852
Errors in the interpretation of copy number variations due to the use of public databases as a reference
(Elsevier, 2014-03-14)
The identification of new cryptic deletions and duplications can be used to improve prognostic classification in cancer. To obtain accurate results, it is necessary to discriminate between somatic alterations in the tumor ...
C24:0 and C24:1 sphingolipids in cholesterol-containing, five- and six-component lipid membranes
(Nature, 2020-08-24)
The biophysical properties of sphingolipids containing lignoceric (C24:0) or nervonic (C24:1) fatty acyl residues have been studied in multicomponent lipid bilayers containing cholesterol (Chol), by means of confocal ...
Lipid Self-Assemblies under the Atomic Force Microscope
(MDPI, 2021-09-18)
Lipid model membranes are important tools in the study of biophysical processes such as lipid self-assembly and lipid–lipid interactions in cell membranes. The use of model systems to adequate and modulate complexity helps ...
Spin Hall magnetoresistance at Pt/CoFe2O4 interfaces and texture effects
(AIP publishing, 2014-10-08)
We report magnetoresistance measurements on thin Pt bars grown on epitaxial (001) and (111) CoFe2O4 (CFO) ferrimagnetic insulating films. The results can be described in terms of the recently discovered spin Hall ...
CHO/LY-B Cell Growth under Limiting Sphingolipid Supply: Correlation between Lipid Composition and Biophysical Properties of Sphingolipid-Restricted Cell Membranes
(Wiley, 2021-06)
Sphingolipids (SL) are ubiquitous in mammalian cell membranes, yet there is little data on the behavior of cells under SL- restriction conditions. LY- B cells derive from a CHO linein whichserine palmitoyl transferase ...
Erythrocyte Membrane Nanomechanical Rigidity Is Decreased in Obese Patients
(MDPI, 2022-02-08)
This work intends to describe the physical properties of red blood cell (RBC) membranes in obese adults. The hypothesis driving this research is that obesity, in addition to increasing the amount of body fat, will also ...
Stiffening near-net-shape functional parts of Inconel 718 LPBF considering material anisotropy and subsequent machining issues
(Elsevier, 2021-12-24)
[EN] Additive manufacturing of metallic parts has witnessed significant development. The laser powder bed fusion (LPBF) process has emerged as a key process for manufacturing thin-walled components. However, despite the ...
Strategic knowledge-based approach for CAD modelling learning
(Springer, 2018-10-01)
Strategic knowledge is a differentiating factor for conveying the design intent when modelling parts in parametric feature-based CAD systems. Nevertheless, it is rarely considered in training or, when it is tackled, it ...
Plasma membrane effects of sphingolipid-synthesis inhibition by myriocin in CHO cells: a biophysical and lipidomic study
(Nature Research, 2022)
[EN] Suppression of a specific gene effect can be achieved by genetic as well as chemical methods. Each approach may hide unexpected drawbacks, usually in the form of side effects. In the present study, the specific inhibitor ...