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CHO/LY-B Cell Growth under Limiting Sphingolipid Supply: Correlation between Lipid Composition and Biophysical Properties of Sphingolipid-Restricted Cell Membranes
(Wiley, 2021-06)
Sphingolipids (SL) are ubiquitous in mammalian cell membranes, yet there is little data on the behavior of cells under SL- restriction conditions. LY- B cells derive from a CHO linein whichserine palmitoyl transferase ...
Erythrocyte Membrane Nanomechanical Rigidity Is Decreased in Obese Patients
(MDPI, 2022-02-08)
This work intends to describe the physical properties of red blood cell (RBC) membranes in obese adults. The hypothesis driving this research is that obesity, in addition to increasing the amount of body fat, will also ...
Stiffening near-net-shape functional parts of Inconel 718 LPBF considering material anisotropy and subsequent machining issues
(Elsevier, 2021-12-24)
[EN] Additive manufacturing of metallic parts has witnessed significant development. The laser powder bed fusion (LPBF) process has emerged as a key process for manufacturing thin-walled components. However, despite the ...
Strategic knowledge-based approach for CAD modelling learning
(Springer, 2018-10-01)
Strategic knowledge is a differentiating factor for conveying the design intent when modelling parts in parametric feature-based CAD systems. Nevertheless, it is rarely considered in training or, when it is tackled, it ...
Plasma membrane effects of sphingolipid-synthesis inhibition by myriocin in CHO cells: a biophysical and lipidomic study
(Nature Research, 2022)
[EN] Suppression of a specific gene effect can be achieved by genetic as well as chemical methods. Each approach may hide unexpected drawbacks, usually in the form of side effects. In the present study, the specific inhibitor ...
Power module electronics in HEVEV applications New trends in widebandgap semiconductor technologies and design aspects
(Elsevier, 2019-08-02)
A large number of factors such as the increasingly stringent pollutant emission policies, fossil fuel scarcity and their price volatility have increased the interest towards the partial or total electrification of current ...
The role of power device technology in the electric vehicle powertrain
(Wiley, 2022-12)
In the automotive industry, the design and implementation of power converters and especially inverters, are at a turning point. Silicon (Si) IGBTs are at present the most widely used power semiconductors in most commercial ...
Next generation electric drives for HEV/EV propulsion systems: Technology, trends and challenges
(Elsevier, 2019-08-23)
In recent decades, several factors such as environmental protection, fossil fuel scarcity, climate change and pollution have driven the research and development of a more clean and sustainable transport. In this context, ...
Wide Bandgap semiconductor HF-oscillation attenuation method with tuned gate RLC filter
(IEEE, 2020-01-06)
Wide Bandgap (WBG) transistors provide better switching performance and higher operating temperatures compared to state of the art Si devices and are suited for high frequency applications due to very short switching times. ...
The power flow and the wave energy flux at an operational wave farm: Findings from Mutriku, Bay of Biscay
(Elservier, 2021-04-14)
Mutriku is a wave farm on the Spanish coast of the Bay of Biscay that has now been continuously supplying electricity for more than nine years. Since 1979, there has been a growing trend in wave energy flux for the whole ...