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Pharmacogenetics of MicroRNAs and MicroRNAs Biogenesis Machinery in Pediatric Acute Lymphoblastic Leukemia
(Public Library Science, 2014-03-10)
Despite the clinical success of acute lymphoblastic leukemia (ALL) therapy, toxicity is frequent. Therefore, it would be useful to identify predictors of adverse effects. In the last years, several studies have investigated ...
Is Social Media a New Type of Social Support? Social Media Use in Spain during the COVID-19 Pandemic: A Mixed Methods Study
(MDPI, 2022-03-26)
This study examines Spanish adults’ social media use during the COVID-19 pandemic using mixed-methods to assess and understand frequency, context, and changes in social media use during two critical time points in Spain. ...
The Emotional Divergent–Convergent Thinking Program (EDICOP): Design, Implementation, and Results
(MDPI, 2020-11-13)
In a social environment that requires young people to adapt to increasingly demanding situations, emotional education and creativity training may be key for both personal development and academic performance. Given that ...
Age‐related cognitive decline in myotonic dystrophy type 1: An 11‐year longitudinal follow‐up study
(Wiley, 2020-03)
Background Myotonic dystrophy type 1 (DM1) is an inherited multi-systemic disease involving the central nervous system (CNS) and is consequently characterized by a range of cognitive impairments. However, whether this ...
The Sailor diagram – A new diagram for the verification of two-dimensional vector data from multiple models
(Copernicus Gesellschaft, 2020-07-15)
A new diagram is proposed for the verification of vector quantities generated by multiple models against a set of observations. It has been designed with the objective, as in the Taylor diagram, of providing a visual ...
Optimal strategies of deployment of far offshore co-located wind-wave energy farms
(Elsevier, 2022-01-01)
[EN] The most profitable offshore energy resources are usually found away from the coast. Nevertheless, the accessibility and grid integration in those areas are more complicated. To avoid this problematic, large scale ...
Systematic Review of Pharmacogenetic Factors That Influence High-Dose Methotrexate Pharmacokinetics in Pediatric Malignancies
(MDPI, 2021-06-07)
Methotrexate (MTX) is a mainstay therapeutic agent administered at high doses for the treatment of pediatric and adult malignancies, such as acute lymphoblastic leukemia, osteosarcoma, and lymphoma. Despite the vast evidence ...
A Comprehensive Study of Vesicular and Non-Vesicular miRNAs from a Volume of Cerebrospinal Fluid Compatible with Clinical Practice
(Ivyspring International Publisher, 2019)
Cerebrospinal fluid (CSF) microRNAs (miRNAs) have emerged as potential biomarkers for minimally invasive diagnosis of central nervous system malignancies. However, despite significant advances in recent years, this field ...
Combining random forests and physics-based models to forecast the electricity generated by ocean waves: A case study of the Mutriku wave farm
(Pergamon-Elsevier, 2019-10-01)
This paper combines random forests with physics-based models to forecast the electricity output of the Mutriku wave farm on the Bay of Biscay. The period analysed was 2014-2016, and the forecast horizon was 24 h in 4-h ...
Global estimations of wind energy potential considering seasonal air density changes
(Pergamon-Elsevier, 2019-11-15)
The literature typically considers constant annual average air density when computing the wind energy potential of a given location. In this work, the recent reanalysis ERA5 is used to obtain global seasonal estimates of ...