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Incidence of mental disorders in the general population aged 1–30 years disaggregated by gender and socioeconomic status
(Springer, 2023-01)
Purpose
The objective of this study was to estimate the incidence and age of onset of mental disorders diagnosed by gender and socioeconomic status (SES) in children, adolescents, and young adults up to 30 years of age ...
Target cell-specific plasticity rules of NMDA receptor-mediated synaptic transmission in the hippocampus
(Frontiers Media, 2023-04)
Long-term potentiation and depression of NMDA receptor-mediated synaptic transmission (NMDAR LTP/LTD) can significantly impact synapse function and information transfer in several brain areas. However, the mechanisms that ...
Influence of ocular biometric factors on the defocus curve in an enlarged depth-of-focus intraocular lens
(Springer, 2023-03)
Background
To assess the influence of biometric measurements on the defocus curve after the implantation of enlarged depth-of-focus (EDoF) intraocular lens (IOL).
Methods
Patients who underwent cataract surgery with ...
The Long-Term Neuroprotective Effect of the Endocannabinoid 2-AG and Modulation of the SGZ’s Neurogenic Response after Neonatal Hypoxia-Ischemia
(MDPI, 2023-06-07)
Neonatal hypoxia-ischemia (HI) often causes hypoxic-ischemic encephalopathy (HIE), a neurological condition that can lead to overall disability in newborns. The only treatment available for affected neonates is therapeutic ...
Alterations of Oligodendrocyte and Myelin Energy Metabolism in Multiple Sclerosis
(MDPI, 2023-08-18)
Multiple sclerosis (MS) is a complex autoimmune disease of the central nervous system (CNS), characterized by demyelination and neurodegeneration. Oligodendrocytes play a vital role in maintaining the integrity of myelin, ...
The Role of Premorbid IQ and Age of Onset as Useful Predictors of Clinical, Functional Outcomes, and Recovery of Individuals with a First Episode of Psychosis
(MDPI, 2021-06-02)
Background: premorbid IQ (pIQ) and age of onset are predictors of clinical severity and long-term functioning after a first episode of psychosis. However, the additive influence of these variables on clinical, functional, ...
Cost-utility analysis of the UPRIGHT intervention promoting resilience in adolescents
(BMC, 2023-03)
Background
As mental health in adulthood is related to mental status during adolescence, school-based interventions have been proposed to improve resilience. The objective of this study was to build a simulation model ...
The Spanish version of the reflective functioning questionnaire: Validity data in the general population and individuals with personality disorders.
(Public Library Science, 2023-04)
Introduction
Mentalization or reflective functioning (RF) is the capacity to interpret oneself or the others in terms of internal mental states. Its failures have been linked to several mental disorders and interventions ...
Effects of Cannabidiol, Hypothermia, and Their Combination in Newborn Rats with Hypoxic-Ischemic Encephalopathy
(Society for Neuroscience, 2023-04)
Therapeutic hypothermia is well established as a standard treatment for infants with hypoxic-ischemic (HI) encephalopathy but it is only partially effective. The potential for combination treatments to augment hypothermic ...
Cerebrolysin Attenuates Exacerbation of Neuropathic Pain, Blood-spinal Cord Barrier Breakdown and Cord Pathology Following Chronic Intoxication of Engineered Ag, Cu or Al (50–60 nm) Nanoparticles
(Springer, 2023-01)
Neuropathic pain is associated with abnormal sensations and/or pain induced by non-painful stimuli, i.e., allodynia causing burning or cold sensation, pinching of pins and needles like feeling, numbness, aching or itching. ...