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Areas of interest and sentiment analysis towards second generation antipsychotics, lithium and mood stabilizing anticonvulsants: Unsupervised analysis using Twitter
(Elsevier, 2024-04)
Background
Severe mental disorders like Schizophrenia and related psychotic disorders (SRD) or Bipolar Disorder (BD) require pharmacological treatment for relapse prevention and quality of life improvement. Yet, treatment ...
A nonlinear meccano for Alzheimer's emergence by amyloid β-mediated glutamatergic hyperactivity
(Elsevier, 2024-05)
The pathophysiological process of Alzheimer's disease (AD) is believed to begin many years before the formal diagnosis of AD dementia. This protracted preclinical phase offers a crucial window for potential therapeutic ...
Oocyte electroporation prior to in vitro fertilization is an efficient method to generate single, double, and multiple knockout porcine embryos of interest in biomedicine and animal production
(Elsevier, 2024-04)
Genetically modified pigs play a critical role in mimicking human diseases, xenotransplantation, and the development of pigs resistant to viral diseases. The use of programmable endonucleases, including the CRISPR/Cas9 ...
Sexually transmitted infections, sexual life and risk behaviours of people living with schizophrenia: systematic review and meta-analysis
(Cambridge University Press, 2024)
Background
Sexually transmitted infections (STIs), along with sexual health and behaviour, have received little attention in schizophrenia patients.
Aims
To systematically review and meta-analytically characterise ...
The effect of omega-3 fatty acids on alcohol-induced damage
(Frontiers Media, 2023-04)
Alcohol is the most widely consumed psychoactive substance in the world that has a severe impact on many organs and bodily systems, particularly the liver and nervous system. Alcohol use during pregnancy roots long-lasting ...
A validated WAIS-IV short-form to estimate intellectual functioning in myotonic dystrophy type 1
(Elsevier, 2022-09)
Currently, no rapid and specific instrument is available to briefly estimate intelligence in patients with myotonic dystrophy type 1 (DM1), a multisystemic disease that involves the CNS and is associated with cognitive ...
Plasma and serum alpha-synuclein as a biomarker in Parkinson's disease: A meta-analysis
(Elsevier, 2022-06)
Background
Reliable biomarkers for Parkinson's disease (PD) diagnosis are urgently needed. Alpha-synuclein (α-syn) and its proteoforms play a key role in PD pathology but in vivo measurements have raised conflicting ...