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Antimicrobial Peptides with Anti-Candida Activity
(MDPI, 2022-08-17)
[EN] Mycoses are accountable for millions of infections yearly worldwide. Invasive candidiasis is the most usual, presenting a high morbidity and mortality. Candida albicans remains the prevalent etiologic agent, but the ...
Virulence of Candida Auris from Different Clinical Origins in Caenorhabditis Elegans and Galleria Mellonella Host Models
(Taylor & Francis, 2021-01-01)
Candida auris is an emerging multidrug-resistant fungal pathogen responsible for nosocomial outbreaks of invasive candidiasis. Although several studies on the pathogenicity of this species have been reported, the knowledge ...
In vitro and in vivo anti-Candida activity of citral in combination with fluconazole
(Taylor & Francis, 2022)
[EN] Background The ability of Candida to develop biofilms on inert surfaces or living tissues favors recalcitrant and chronic candidiasis associated, in many instances, with resistance to current antifungal therapy. Aim ...
Antifungal Activity of the Human Uterine Cervical Stem Cells Conditioned Medium (hUCESC-CM) Against Candida albicans and Other Medically Relevant Species of Candida
(Frontiers Media, 2018-11-21)
Candidiasis is a major cause of human morbidity and mortality. Human uterine cervical stem cells conditioned medium (hUCESC-CM) is obtained from stromal stem cells of the cervical transformation zone, which are in permanent ...
Candidiasis by Candida glabrata, Candida nivariensis and Candida bracarensis in Galleria mellonella: Virulence and Therapeutic Responses to Echinocandins
(MDPI, 2021-11-23)
Candida albicans is the major etiological agent of invasive candidiasis but the increasing prevalence of emerging species of Candida, such as Candida glabrata and phylogenetically closely related species, Candida nivariensis ...
In vitro activities of carvacrol, cinnamaldehyde and thymol against Candida biofilms
(Elsevier, 2021-11)
[EN]Oral candidiasis is frequently associated with Candida biofilms. Biofilms are microbial communities related to persistent, recalcitrant and difficult to-treat infections. Conventional treatments are not sufficient to ...
Caenorhabditis elegans as a Model System To Assess Candida glabrata, Candida nivariensis, and Candida bracarensis Virulence and Antifungal Efficacy
(American Society for Microbiology (ASM), 2020-09-21)
Although Candida albicans remains the major etiological agent of invasive
candidiasis, Candida glabrata and other emerging species of Candida are
increasingly isolated. This species is the second most prevalent cause of ...
Prevalence and antifungal susceptibility profiles of Candida glabrata, Candida parapsilosis and their close-related species in oral candidiasis
(Elsevier, 2018-11)
Objective: To evaluate the importance of Candida glabrata, Candida parapsilosis and their close-related species, Candida bracarensis, Candida nivariensis, Candida metapsilosis and Candida orthopsilosis in patients with ...
Utility of two PCR-RFLP-based techniques for identification of Candida parapsilosis complex blood isolates
(Wiley-Blackwell, 2020-05)
Background: Candida parapsilosis is the second or third most frequently isolated
Candida species related to nosocomial infections, even overtaking Candida albicans
in some hospitals. C. parapsilosis constitutes a complex ...
Efficacy of the combination of amphotericin B and echinocandins against Candida auris in vitro and in the Caenorhabditis elegans host model
(American Society of Microbiology, 2024-01)
The multidrug-resistant Candida auris is a global health emergency, being responsible for outbreaks of invasive candidiasis worldwide. Limited effective therapeutic options make it difficult to treat this emerging pathogen. ...