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Delta(9)-Tetrahydrocannabinol Promotes Oligodendrocyte Development and CNS Myelination in Vivo
(Wiley, 2021-03)
Delta(9)-Tetrahydrocannabinol (THC), the main bioactive compound found in the plantCannabis sativa, exerts its effects by activating cannabinoid receptors present in many neural cells. Cannabinoid receptors are also ...
Endocannabinoid signaling in brain diseases: Emerging relevance of glial cells
(Wiley, 2023-01)
The discovery of cannabinoid receptors as the primary molecular targets of psychotropic cannabinoid Delta(9)-tetrahydrocannabinol (Delta(9)-THC) in late 1980s paved the way for investigations on the effects of cannabis-based ...
Gene Expression Analysis of Astrocyte and Microglia Endocannabinoid Signaling during Autoimmune Demyelination
(MDPI, 2020-08-24)
The endocannabinoid system is associated with protective effects in multiple sclerosis (MS) that involve attenuated innate immune cell responses. Astrocytes and microglia are modulated by endocannabinoids and participate ...