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Influence of MUC5B gene on antisynthetase syndrome
(Nature, 2020-01-29)
MUC5B rs35705950 (G/T) is strongly associated with idiopathic pulmonary fibrosis (IPF) and also contributes to the risk of interstitial lung disease (ILD) in rheumatoid arthritis (RA-ILD) and chronic hypersensitivity ...
Influence of MUC5B gene on antisynthetase syndrome
(Nature, 2020-01-29)
MUC5B rs35705950 (G/T) is strongly associated with idiopathic pulmonary fibrosis (IPF) and also contributes to the risk of interstitial lung disease (ILD) in rheumatoid arthritis (RA-ILD) and chronic hypersensitivity ...
Hole-in-one: simple non-surgical technique for the management of anterior chamber migrated Ozurdex implant
(GMS, 2020-02-27)
Introduction: The migration of a dexamethasone implant to the anterior chamber is a vision-threatening complication which can happen in non-compartmentalized eyes treated with this device. Previous literature suggests that ...
Primary biliary cholangitis: pathogenic mechanisms
(2021-03)
Purpose of review
Primary biliary cholangitis (PBC) is characterized by autoimmune damage of intrahepatic bile ducts associated with a loss of tolerance to mitochondrial antigens. PBC etiopathogenesis is intriguing ...
rs641738C>T nearMBOAT7is associated with liver fat, ALT and fibrosis in NAFLD: A meta-analysis
(Elsevier, 2021-01)
Background & Aims: A common genetic variant near MBOAT7 (rs641738C>T) has been previously associated with hepatic fat and advanced histology in NAFLD; however, these findings have not been consistently replicated in the ...
Urinary Tartaric Acid, a Biomarker of Wine Intake, Correlates with Lower Total and LDL Cholesterol
(MDPI, 2021-08-22)
Postmenopausal women are at higher risk of developing cardiovascular diseases due to changes in lipid profile and body fat, among others. The aim of this study was to evaluate the association of urinary tartaric acid, a ...
Clinical features and outcomes of Streptococcus anginosus group infective Endocarditis: a multicenter matched cohort study
(Oxford University Press, 2021-03-29)
[EN] Background. Although Streptococcus anginosus group (SAG) endocarditis is considered a severe disease associated with abscess
formation and embolic events, there is limited evidence to support this assumption.
Methods. ...
Immune Checkpoint Inhibitors: The Emerging Cornerstone in Cholangiocarcinoma Therapy?
(Karger, 2021-09)
[EN]Background: Cholangiocarcinoma (CCA) encompasses a heterogeneous group of malignant tumors with dismal prognosis and increasing incidence worldwide. Both late diagnosis due to the lack of early symptoms and the refractory ...
Melatonin Protects Cholangiocytes from Oxidative Stress-Induced Proapoptotic and Proinflammatory Stimuli via miR-132 and miR-34
(MDPI, 2020-12-18)
Biosynthesis of melatonin by cholangiocytes is essential for maintaining the function of biliary epithelium. However, this cytoprotective mechanism appears to be impaired in primary biliary cholangitis (PBC). MiR-132 has ...