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A survey on the use of mice, pigs, dogs and monkeys as animal models in biomedical research in Spain
(Springernature, 2022)
[EN] Background The use of animals in biomedical science remains controversial. An individual's level of concern is generally influenced by their culture, previous or current experience with animals, and the specific animal ...
Looking Backward to Move Forward: a Meta-Analysis of Stem Cell Therapy in Amyotrophic Lateral Sclerosis
(Springer, 2021-04-01)
Transplantation of several types of stem cells (SC) for the treatment of amyotrophic lateral sclerosis (ALS) has been evaluated in numerous Phase I/II clinical trials with inconclusive results. Here, we conducted a ...
Postweaning Grouping as a Strategy to Reduce Singly Housed Male Mice
(MDPI, 2020-11-17)
Rearing laboratory mice in groups is important since social isolation after weaning induces brain alterations, which entails behavioral abnormalities in adulthood. Age is an important factor when grouping males of different ...
Professional Quality of Life in Research Involving Laboratory Animals
(MDPI, 2021-09-08)
Many workers contribute to the success of animal welfare and study outcomes in biomedical research. However, the professional quality of life (ProQoL) of those who work with laboratory animals has not been explored in ...
Working with laboratory rodents in Spain: a survey on welfare and wellbeing
(Springer Nature, 2021-07-27)
[EN] Background: Replacement, reduction and refinement, the 3R principles, provide a framework to minimize the use
and suffering of animals in science. In this context, we aimed to determine the actual perception that ...
Mice in translational neuroscience: What R we doing?
(Elsevier, 2022-10)
Animal models play a pivotal role in translational neuroscience but recurrent problems in data collection, an-alyses, and interpretation, lack of biomarkers, and a tendency to over-reliance on mice have marred neuroscience ...
Professional quality of life among Spanish veterinarians
(Wiley, 2022-12)
BackgroundIn: Spain, the perceived professional quality of life among veterinarians has not been explored.
Methods: Veterinarians were invited to complete an online questionnaire in which they answered the Professional ...
Refinement in the European Union: A Systematic Review
(MDPI, 2022-11-23)
Refining experiments and housing conditions so as to cause the minimum possible pain and distress is one of the three principles (3Rs) on which Directive 2010/63/EU is based. In this systematic review, we aimed to identify ...
Individualized Housing Modifies the Immune–Endocrine System in CD1 Adult Male Mice
(MDPI, 2023-03-10)
In the last years, different research groups have made considerable efforts to improve the care and use of animals in research. Mice (Mus musculus) are the most widely used animal species in research in the European Union ...
Implementing the 3Rs in Laboratory Animal Research - From Theory to Practice
(MDPI, 2023-09-29)
Editorial of the Special Issue "Implementing the 3Rs in Laboratory Animal Research—From Theory to Practice"