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The Cryo-EM Structure of a Complete 30S Translation Initiation Complex from Escherichia coli
(Public Library of Science, 2011-07-05)
Formation of the 30S initiation complex (30S IC) is an important checkpoint in regulation of gene expression. The selection of mRNA, correct start codon, and the initiator fMet-tRNA(fMet) requires the presence of three ...
Increased expression of cystine/glutamate antiporter in multiple sclerosis
(BioMed Central, 2011-06-03)
Background: Glutamate excitotoxicity contributes to oligodendrocyte and tissue damage in multiple sclerosis (MS). Intriguingly, glutamate level in plasma and cerebrospinal fluid of MS patients is elevated, a feature which ...