dc.contributor.author | Laín Torre, Ana | |
dc.contributor.author | Elguezabal Vega, Natalia María | |
dc.contributor.author | Amutio, Elena | |
dc.contributor.author | Fernández de Larrinoa Santamaría, Iñigo | |
dc.contributor.author | Moragues Tosantos, María Dolores | |
dc.contributor.author | Pontón, José | |
dc.date.accessioned | 2011-06-08T14:58:51Z | |
dc.date.available | 2011-06-08T14:58:51Z | |
dc.date.issued | 2008 | |
dc.identifier.citation | Clinical and Developmental Immunology 2008 : (2008) // Article ID 721950 | es |
dc.identifier.issn | 1740-2522 | |
dc.identifier.uri | http://hdl.handle.net/10810/2774 | |
dc.description | 7 p. | es |
dc.description.abstract | Invasive candidiasis is a frequent and often fatal complication in immunocompromised and critically ill patients. Unfortunately, the diagnosis of invasive candidiasis remains difficult due to the lack of specific clinical symptoms and a definitive diagnostic method. The detection of antibodies against different Candida antigens may help in the diagnosis. However, the methods traditionally used for the detection of antibodies have been based on crude antigenic fungal extracts, which usually show low-reproducibility and cross-reactivity problems. The development of molecular biology techniques has allowed the production of recombinant antigens which may help to solve these problems. In this review we will discuss the usefulness of recombinant antigens in the diagnosis of invasive candidiasis. | es |
dc.description.sponsorship | Research performed in the authors’ laboratories
has been financed by Grants PI040556 from Fondo de Investigación Sanitaria and
GIU06/56 from Universidad del País Vasco. | es |
dc.language.iso | eng | es |
dc.publisher | Hindawi Publishing Corporation | es |
dc.rights | info:eu-repo/semantics/openAccess | es |
dc.subject | albicans germ tubes | es |
dc.subject | linked immunosorbent assay | es |
dc.subject | ALS gene family | es |
dc.subject | systemic candidiasis | es |
dc.subject | virulence factors | es |
dc.subject | wall protein | es |
dc.subject | enolase | es |
dc.subject | antibodies | es |
dc.subject | serodiagnosis | es |
dc.subject | expression | es |
dc.title | Use of Recombinant Antigens for the Diagnosis of Invasive Candidiasis | es |
dc.type | info:eu-repo/semantics/article | es |
dc.rights.holder | Copyright © 2008 Ana Laín et al. This is an open access article distributed under the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | es |
dc.relation.publisherversion | http://www.hindawi.com/journals/cdi/2008/721950/ | es |
dc.identifier.doi | 10.1155/2008/721950 | |
dc.departamentoes | Enfermería | es_ES |
dc.departamentoes | Inmunología, microbiología y parasitología | es_ES |
dc.departamentoes | Química aplicada | es_ES |
dc.departamentoeu | Erizaintza | es_ES |
dc.departamentoeu | Immunologia, mikrobiologia eta parasitologia | es_ES |
dc.departamentoeu | Kimika aplikatua | es_ES |
dc.subject.categoria | IMMUNOLOGY AND ALLERGY | |
dc.subject.categoria | IMMUNOLOGY AND MICROBIOLOGY | |