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dc.contributor.authorLaín Torre, Ana
dc.contributor.authorElguezabal Vega, Natalia María
dc.contributor.authorAmutio, Elena
dc.contributor.authorFernández de Larrinoa Santamaría, Iñigo
dc.contributor.authorMoragues Tosantos, María Dolores ORCID
dc.contributor.authorPontón, José
dc.date.accessioned2011-06-08T14:58:51Z
dc.date.available2011-06-08T14:58:51Z
dc.date.issued2008
dc.identifier.citationClinical and Developmental Immunology 2008 : (2008) // Article ID 721950es
dc.identifier.issn1740-2522
dc.identifier.urihttp://hdl.handle.net/10810/2774
dc.description7 p.es
dc.description.abstractInvasive candidiasis is a frequent and often fatal complication in immunocompromised and critically ill patients. Unfortunately, the diagnosis of invasive candidiasis remains difficult due to the lack of specific clinical symptoms and a definitive diagnostic method. The detection of antibodies against different Candida antigens may help in the diagnosis. However, the methods traditionally used for the detection of antibodies have been based on crude antigenic fungal extracts, which usually show low-reproducibility and cross-reactivity problems. The development of molecular biology techniques has allowed the production of recombinant antigens which may help to solve these problems. In this review we will discuss the usefulness of recombinant antigens in the diagnosis of invasive candidiasis.es
dc.description.sponsorshipResearch performed in the authors’ laboratories has been financed by Grants PI040556 from Fondo de Investigación Sanitaria and GIU06/56 from Universidad del País Vasco.es
dc.language.isoenges
dc.publisherHindawi Publishing Corporationes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectalbicans germ tubeses
dc.subjectlinked immunosorbent assayes
dc.subjectALS gene familyes
dc.subjectsystemic candidiasises
dc.subjectvirulence factorses
dc.subjectwall proteines
dc.subjectenolasees
dc.subjectantibodieses
dc.subjectserodiagnosises
dc.subjectexpressiones
dc.titleUse of Recombinant Antigens for the Diagnosis of Invasive Candidiasises
dc.typeinfo:eu-repo/semantics/articlees
dc.rights.holderCopyright © 2008 Ana Laín et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.es
dc.relation.publisherversionhttp://www.hindawi.com/journals/cdi/2008/721950/es
dc.identifier.doi10.1155/2008/721950
dc.departamentoesEnfermeríaes_ES
dc.departamentoesInmunología, microbiología y parasitologíaes_ES
dc.departamentoesQuímica aplicadaes_ES
dc.departamentoeuErizaintzaes_ES
dc.departamentoeuImmunologia, mikrobiologia eta parasitologiaes_ES
dc.departamentoeuKimika aplikatuaes_ES
dc.subject.categoriaIMMUNOLOGY AND ALLERGY
dc.subject.categoriaIMMUNOLOGY AND MICROBIOLOGY


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