Antibiotic Use in Febrile Children Presenting to the Emergency Department: a Systematic Review
dc.contributor.author | Van De Voort, Elles | |
dc.contributor.author | Mintegi Raso, Santiago | |
dc.contributor.author | Gervaix, Alain | |
dc.contributor.author | Moll, Henriette A. | |
dc.contributor.author | Oostenbrink, Rianne | |
dc.date.accessioned | 2018-12-14T09:43:42Z | |
dc.date.available | 2018-12-14T09:43:42Z | |
dc.date.issued | 2018-10-08 | |
dc.identifier.citation | Frontiers In Pediatrics 6 : (2018) // Article ID 260 | es_ES |
dc.identifier.issn | 2296-2360 | |
dc.identifier.uri | http://hdl.handle.net/10810/30346 | |
dc.description.abstract | Introduction: While fever is the main complaint among pediatric emergency services and high antibiotic prescription are observed, only a few studies have been published addressing this subject. Therefore this systematic review aims to summarize antibiotic prescriptions in febrile children at the ED and assess its determinants. Methods: We extracted studies published from 2000 to 2017 on antibiotic use in febrile children at the ED from different databases. Author, year, and country of publishing, study design, inclusion criteria, primary outcome, age, and number of children included in the study was extracted. To compare the risk-of-bias all articles were assessed using the MINORS criteria. For the final quality assessment we additionally used the sample size and the primary outcome. Results: We included 26 studies reporting on antibiotic prescription and 28 intervention studies on the effect on antibiotic prescription. In all 54 studies antibiotic prescriptions in the ED varied from 15 to 90.5%, pending on study populations and diagnosis. Respiratory tract infections were mostly studied. Pediatric emergency physicians prescribed significantly less antibiotics then general emergency physicians. Most frequent reported interventions to reduce antibiotics are delayed antibiotic prescription in acute otitis media, viral testing and guidelines. Conclusion: Evidence on antibiotic prescriptions in children with fever presenting to the ED remains inconclusive. Delayed antibiotic prescription in acute otitis media and guidelines for fever and respiratory infections can effectively reduce antibiotic prescription in the ED. The large heterogeneity of type of studies and included populations limits strict conclusions, such a gap in knowledge on the determining factors that influence antibiotic prescription in febrile children presenting to the ED remains. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Frontiers Media SA | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | * |
dc.subject | pediatric emergency care | es_ES |
dc.subject | fever | es_ES |
dc.subject | children | es_ES |
dc.subject | antibiotic prescription | es_ES |
dc.subject | management | es_ES |
dc.subject | acute otitis-media | es_ES |
dc.subject | respiratory-tract infections | es_ES |
dc.subject | serious bacterial-infections | es_ES |
dc.subject | randomized clinical-trial | es_ES |
dc.subject | C-reactive protein | es_ES |
dc.subject | localizing signs | es_ES |
dc.subject | rapid diagnosis | es_ES |
dc.subject | prescribing antibiotics | es_ES |
dc.subject | primary-care | es_ES |
dc.title | Antibiotic Use in Febrile Children Presenting to the Emergency Department: a Systematic Review | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.holder | Copyright © 2018 van de Voort, Mintegi, Gervaix, Moll and Oostenbrink. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. | es_ES |
dc.rights.holder | Atribución 3.0 España | * |
dc.relation.publisherversion | https://www.frontiersin.org/articles/10.3389/fped.2018.00260/full | es_ES |
dc.identifier.doi | 10.3389/fped.2018.00260 | |
dc.departamentoes | Pediatría | es_ES |
dc.departamentoeu | Pediatria | es_ES |
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Except where otherwise noted, this item's license is described as Copyright © 2018 van de Voort, Mintegi, Gervaix, Moll and Oostenbrink. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.