dc.contributor.author | Urgoitia Gabikaetxebarria, Garazi | |
dc.contributor.author | San Martín Faces, Raúl | |
dc.contributor.author | Herrero Corral, María Teresa | |
dc.contributor.author | Domínguez Pérez, Pilar Esther | |
dc.date.accessioned | 2019-03-07T11:57:15Z | |
dc.date.available | 2019-03-07T11:57:15Z | |
dc.date.issued | 2018-12-08 | |
dc.identifier.citation | Catalysts 8(12) : (2018) // Article ID 640 | es_ES |
dc.identifier.issn | 2073-4344 | |
dc.identifier.uri | http://hdl.handle.net/10810/31903 | |
dc.description.abstract | Csp(3)-H oxidation of benzylic methylene compounds is an established strategy for the synthesis of aromatic ketones, esters, and amides. The need for more sustainable oxidizers has encouraged researchers to explore the use of molecular oxygen. In particular, homogeneous metal-catalyzed aerobic oxidation of benzylic methylenes has attracted much attention. This account summarizes the development of this oxidative strategy in the last two decades, examining key factors such as reaction yields, substrate: catalyst ratio, substrate scope, selectivity over other oxidation byproducts, and reaction conditions including solvents and temperature. Finally, several mechanistic proposals to explain the observed results will be discussed. | es_ES |
dc.description.sponsorship | (IT-774-13 (Basque Government) and CTQ2017-86630-P (Spanish Ministry of Economy and Competitiveness) projects. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | MDPI | es_ES |
dc.relation | info:eu-repo/grantAgreement/MINECO/CTQ2017-86630-P | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | * |
dc.subject | oxidation | es_ES |
dc.subject | molecular oxygen | es_ES |
dc.subject | metal catalysts | es_ES |
dc.subject | aryl ketones | es_ES |
dc.subject | benzoate esters | es_ES |
dc.subject | benzamides | es_ES |
dc.subject | liquid-phase oxidation | es_ES |
dc.subject | enzymatic allylic oxidations | es_ES |
dc.subject | n-hydroxyphthalimide | es_ES |
dc.subject | selective oxidation | es_ES |
dc.subject | alkyl arenes | es_ES |
dc.subject | hydrocarbon oxidation | es_ES |
dc.subject | cobalt nanoparticles | es_ES |
dc.subject | efficient synthesis | es_ES |
dc.subject | mediated oxidation | es_ES |
dc.title | Recent Advances in Homogeneous Metal-Catalyzed Aerobic C–H Oxidation of Benzylic Compounds | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.holder | This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0). | es_ES |
dc.rights.holder | Atribución 3.0 España | * |
dc.relation.publisherversion | https://www.mdpi.com/2073-4344/8/12/640 | es_ES |
dc.identifier.doi | 10.3390/catal8120640 | |
dc.departamentoes | Química orgánica II | es_ES |
dc.departamentoeu | Kimika organikoa II | es_ES |