Self-Healing Hydrogels: The Next Paradigm Shift in Tissue Engineering?
dc.contributor.author | Talebian, S. | |
dc.contributor.author | Mehrali, M. | |
dc.contributor.author | Taebnia, N. | |
dc.contributor.author | Pennisi, C.P. | |
dc.contributor.author | Kadumudi, F.B. | |
dc.contributor.author | Foroughi, J. | |
dc.contributor.author | Hasany, M. | |
dc.contributor.author | Nikkhah, M. | |
dc.contributor.author | Akbari, Mohsen | |
dc.contributor.author | Orive Arroyo, Gorka | |
dc.contributor.author | Dolatshahi-Pirouz, Alireza ![]() | |
dc.date.accessioned | 2019-11-26T10:03:21Z | |
dc.date.available | 2019-11-26T10:03:21Z | |
dc.date.issued | 2019-08-21 | |
dc.identifier.citation | Advanced Science 6(16) : (2019) // Article ID 1801664 | es_ES |
dc.identifier.issn | 2198-3844 | |
dc.identifier.uri | http://hdl.handle.net/10810/36466 | |
dc.description.abstract | Given their durability and long-term stability, self-healable hydrogels have, in the past few years, emerged as promising replacements for the many brittle hydrogels currently being used in preclinical or clinical trials. To this end, the incompatibility between hydrogel toughness and rapid self-healing remains unaddressed, and therefore most of the self-healable hydrogels still face serious challenges within the dynamic and mechanically demanding environment of human organs/tissues. Furthermore, depending on the target tissue, the self-healing hydrogels must comply with a wide range of properties including electrical, biological, and mechanical. Notably, the incorporation of nanomaterials into double-network hydrogels is showing great promise as a feasible way to generate self-healable hydrogels with the above-mentioned attributes. Here, the recent progress in the development of multifunctional and self-healable hydrogels for various tissue engineering applications is discussed in detail. Their potential applications within the rapidly expanding areas of bioelectronic hydrogels, cyborganics, and soft robotics are further highlighted. | es_ES |
dc.description.sponsorship | S.T. and M.M. contributed equally to this work. A.D.P. acknowledges the Danish Council for Independent Research (Technology and Production Sciences, 5054-00142B), Gigtforeningen (R139-A3864) and the Villum Foundation (10103). This work is also part of the VIDI research program with project number R0004387, which is (partly) financed by the Netherlands Organisation for Scientific Research (NWO). The authors acknowledge funding from the Australian Research Council under the Discovery Early Career Researcher Award (J. Foroughi, DE130100517). The authors also thank Ashish for creating Figure 21. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Wiley | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | * |
dc.subject | cyborganics | es_ES |
dc.subject | nanocomposite hydrogels | es_ES |
dc.subject | nanomaterials | es_ES |
dc.subject | self-healing hydrogels | es_ES |
dc.subject | tissue engineering | es_ES |
dc.subject | hyaluronic-acid hydrogels | es_ES |
dc.subject | shear-thinning hydrogels | es_ES |
dc.subject | disulfide bond formation | es_ES |
dc.subject | double-network hydrogel | es_ES |
dc.subject | syringe-injectable electronics | es_ES |
dc.subject | oxide nanocomposite hydrogel | es_ES |
dc.subject | density-functional theory | es_ES |
dc.subject | covalent cross-linking | es_ES |
dc.subject | cell delivery carrier | es_ES |
dc.subject | diels-alder reaction | es_ES |
dc.title | Self-Healing Hydrogels: The Next Paradigm Shift in Tissue Engineering? | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.holder | © 2019 The Authors. Published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. | es_ES |
dc.rights.holder | Atribución 3.0 España | * |
dc.relation.publisherversion | https://www.ncbi.nlm.nih.gov/pubmed?Db=pubmed&Cmd=Retrieve&list_uids=31453048&dopt=abstractplus | es_ES |
dc.identifier.doi | 10.1002/advs.201801664 | |
dc.departamentoes | Farmacia y ciencias de los alimentos | es_ES |
dc.departamentoeu | Farmazia eta elikagaien zientziak | es_ES |
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Except where otherwise noted, this item's license is described as © 2019 The Authors. Published by WILEY-VCH Verlag GmbH & Co. KGaA,
Weinheim. This is an open access article under the terms of the Creative
Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.