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dc.contributor.authorFernández Landa, Julen
dc.contributor.authorCalleja González, Julio María ORCID
dc.contributor.authorLeón Guereño, Patxi
dc.contributor.authorCaballero García, Alberto
dc.contributor.authorCórdova, Alfredo
dc.contributor.authorMielgo Ayuso, Juan Francisco
dc.date.accessioned2020-01-16T11:04:52Z
dc.date.available2020-01-16T11:04:52Z
dc.date.issued2019-10-20
dc.identifier.citationNutrients 11(10) : (2019) // Article ID 2528es_ES
dc.identifier.issn2072-6643
dc.identifier.urihttp://hdl.handle.net/10810/38489
dc.description.abstractAlthough there are many studies showing the isolated effect of creatine monohydrate (CrM) and beta-hydroxy beta-methylbutyrate (HMB), it is not clear what effect they have when they are combined. The main purpose of this systematic review was to determine the efficacy of mixing CrM plus HMB in comparison with their isolated effects on sports performance, body composition, exercise induced markers of muscle damage, and anabolic-catabolic hormones. This systematic review was carried out in accordance with PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement guidelines and the PICOS model, for the definition of the inclusion criteria. Studies were found by searching PubMed/MEDLINE, Web of Science (WOS), and Scopus electronic databases from inception to July 3rd 2019. Methodological quality and risk of bias were assessed by two authors independently, and disagreements were resolved by third-party evaluation, in accordance with the Cochrane Collaboration Guidelines samples. The literature was examined regarding the effects of the combination of CrM plus HMB on sport performance using several outcome variables (athletic performance, body composition, markers of muscle damage, and hormone status). This systematic review included six articles that investigated the effects of CrM plus HMB on sport performance (two on strength performance, showing improvements in one of them; three on anaerobic performance, presenting enhancements in two of them; and one on aerobic performance, not presenting improvements), body composition (three on body mass, showing improvements in one of them; two on fat free mass, presenting increases in one of them; and two on fat mass, showing decreases in one of them) and markers of muscle damage and hormone status (four on markers of muscle damage and one on anabolic-catabolic hormones, not showing benefits in any of them). In summary, the combination of 3-10 g/day of CrM plus 3 g/day of HMB for 1-6 weeks could produce potential positive effects on sport performance (strength and anaerobic performance) and for 4 weeks on body composition (increasing fat free mass and decreasing fat mass). However, this combination seems to not show positive effects relating to markers of exercise-induced muscle damage and anabolic-catabolic hormones.es_ES
dc.language.isoenges_ES
dc.publisherMDPIes_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es/*
dc.subjectsport nutritiones_ES
dc.subjectanaerobices_ES
dc.subjectaerobices_ES
dc.subjectbody compositiones_ES
dc.subjectmuscle recoveryes_ES
dc.subjecthydroxy-beta-methylbutyratees_ES
dc.subjectskeletal-musclees_ES
dc.subjecthmb/creatine supplementationes_ES
dc.subjectresistance-exercisees_ES
dc.subjectmuscular strengthes_ES
dc.subjectblood lactatees_ES
dc.subjectdouble-blindes_ES
dc.subjectmasses_ES
dc.subjectcapacityes_ES
dc.subjectrestrictiones_ES
dc.titleEffect of the Combination of Creatine Monohydrate Plus HMB Supplementation on Sports Performance, Body Composition, Markers of Muscle Damage and Hormone Status: A Systematic Reviewes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.holder© 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/)es_ES
dc.rights.holderAtribución 3.0 España*
dc.relation.publisherversionhttps://www.mdpi.com/2072-6643/11/10/2528/htmes_ES
dc.identifier.doi10.3390/nu11102528
dc.departamentoesEducación física y deportivaes_ES
dc.departamentoeuGorputz eta Kirol Hezkuntzaes_ES


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© 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/)
Except where otherwise noted, this item's license is described as © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/)