Regulation of Male Fertility by the Renin-Angiotensin System
dc.contributor.author | Gianzo Citores, Marta | |
dc.contributor.author | Subirán Ciudad, Nerea | |
dc.date.accessioned | 2020-11-17T13:01:39Z | |
dc.date.available | 2020-11-17T13:01:39Z | |
dc.date.issued | 2020-10-26 | |
dc.identifier.citation | International Journal of Molecular Sciences 21(21) : (2020) // Article ID 7943 | es_ES |
dc.identifier.issn | 1422-0067 | |
dc.identifier.uri | http://hdl.handle.net/10810/48215 | |
dc.description.abstract | The renin-angiotensin system (RAS) is a peptidic system known mainly for its roles in the maintenance of blood pressure and electrolyte and fluid homeostasis. However, several tissues and cells have been described to possess an intrinsic RAS that acts locally through different paracrine and autocrine mechanisms. In the male reproductive system, several components of this system have been observed in various organs and tissues, such as the testes, spermatozoa and seminal fluid. Some functions attributed to this local RAS are maintenance of seminal plasma electrolytes, regulation of steroidogenesis and spermatogenesis, and sperm functions. However, their specific actions in these locations are not fully understood. Therefore, a deep knowledge of the functions of the RAS at both the testicular and seminal levels could clarify its roles in male infertility and sperm physiology, and the different RAS elements could be used to design tools enabling the diagnosis and/or treatment of male infertility. | es_ES |
dc.description.sponsorship | This study was supported by grants from the Basque Government (GIC12/173) and University of the Basque Country (UPV/EHU) (EHUA14/17). | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | MDPI | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | |
dc.subject | renin-angiotensin system | es_ES |
dc.subject | male infertility | es_ES |
dc.subject | angiotensin | es_ES |
dc.subject | renin | es_ES |
dc.subject | testis | es_ES |
dc.subject | spermatozoa | es_ES |
dc.title | Regulation of Male Fertility by the Renin-Angiotensin System | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.date.updated | 2020-11-12T14:13:40Z | |
dc.rights.holder | 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). | es_ES |
dc.relation.publisherversion | https://www.mdpi.com/1422-0067/21/21/7943/htm | es_ES |
dc.identifier.doi | 10.3390/ijms21217943 | |
dc.departamentoes | Fisiología | |
dc.departamentoeu | Fisiologia |
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Except where otherwise noted, this item's license is described as 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).