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dc.contributor.authorSalazar de Pablo, Gonzalo ORCID
dc.contributor.authorDe Michell, Andrea
dc.contributor.authorNieman, Dorien H.
dc.contributor.authorCorrell, Christoph U.
dc.contributor.authorKessing, Lars Vedel
dc.contributor.authorPfennig, Andrea
dc.contributor.authorBechdolf, Andreas
dc.contributor.authorBorgwardt, Stefan
dc.contributor.authorArango, Celso
dc.contributor.authorVan Amelsvoort, Therese
dc.contributor.authorVieta, Eduard
dc.contributor.authorSolmi, Marco
dc.contributor.authorOliver, Dominic
dc.contributor.authorCatalán Alcántara, Ana ORCID
dc.contributor.authorVerdino, Valeria
dc.contributor.authorDi Maggio, Lucia
dc.contributor.authorBonoldi, Ilaria
dc.contributor.authorVaquerizo Serrano, Julio
dc.contributor.authorBoy, Ottone Baccaredda
dc.contributor.authorProvenzani, Umberto
dc.contributor.authorRuzzi, Francesca
dc.contributor.authorCalorio, Federica
dc.contributor.authorNosari, Guido
dc.contributor.authorDi Marco, Benedetto
dc.contributor.authorFamularo, Irene
dc.contributor.authorMolteni, Silvia
dc.contributor.authorFilosi, Eleonora
dc.contributor.authorMensi, Martina
dc.contributor.authorBalottin, Umberto
dc.contributor.authorPoliti, Pierluigi
dc.contributor.authorIl Shin, Jae
dc.contributor.authorFusar-Poli, Paolo
dc.date.accessioned2021-02-03T09:20:25Z
dc.date.available2021-02-03T09:20:25Z
dc.date.issued2020-12
dc.identifier.citationEuropean Neuropsychopharmacology 41 : 28-39 (2020)es_ES
dc.identifier.issn0924-977X
dc.identifier.issn1873-7862
dc.identifier.urihttp://hdl.handle.net/10810/50006
dc.description.abstractPromotion of good mental health in young people is important. Our aim was to evaluate the consistency and magnitude of the efficacy of universal/selective interventions to promote good mental health. A systematic PRISMA/RIGHT-compliant meta-analysis (PROSPERO: CRD42018088708) search of Web of Science until 04/31/2019 identified original studies comparing the efficacy of universal/selective interventions for good mental health vs a control group, in samples with a mean age < 35 years. Meta-analytical random-effects model, heterogeneity statistics, assessment of publication bias, study quality and sensitivity analyses investigated the efficacy (Hedges' g = effect size, ES) of universal/selective interventions to promote 14 good mental health outcomes defined a-priori. 276 studies were included (total participants: 159,508, 79,142 interventions and 80,366 controls), mean age = 15.0 (SD = 7.4); female = 56.0%. There was a significant overall improvement in 10/13 good mental health outcome categories that could be meta-analysed: compared to controls, interventions significantly improved (in descending order of magnitude) mental health literacy (ES = 0.685, p < 0.001), emotions (ES = 0.541, p < 0.001), self-perceptions and values (ES = 0.49, p < 0.001), quality of life (ES = 0.457, p = 0.001), cognitive skills (ES = 0.428, p < 0.001), social skills (ES = 0.371, p < 0.001), physical health (ES = 0.285, p < 0.001), sexual health (ES = 0.257, p = 0.017), academic/occupational performance (ES = 0.211, p < 0.001) and attitude towards mental disorders (ES = 0.177, p = 0.006). Psychoeducation was the most effective intervention for promoting mental health literacy (ES = 0.774, p < 0.001) and cognitive skills (ES = 1.153, p = 0.03). Physical therapy, exercise and relaxation were more effective than psychoeducation and psychotherapy for promoting physical health (ES= 0.498, p<0.001). In conclusion, several universal/selective interventions can be effective to promote good mental health in young people. Future research should consolidate and extend these findings.es_ES
dc.description.sponsorshipThis study was supported by the European College of Neuropsychopharmacology Network Board. Dr Salazar de Pablo is supported by the Alicia Koplowitz Foundation. Dr FusarPoli is supported by the PSYSCAN project through the European Commission. Dr. Correll has been a consultant and/or advisor to or has received honoraria from: Alkermes, Allergan, Angelini, Boehringer-Ingelheim, Gedeon Richter, Gerson Lehrman Group, Indivior, IntraCellular Therapies, Janssen/J&J, LB Pharma, Lundbeck, MedAvante-ProPhase, Medscape, Merck, Neurocrine, Noven, Otsuka, Pfizer, Recordati, Rovi, Servier, Sumitomo Dainippon, Sunovion, Supernus, Takeda, and Teva. He has provided expert testimony for Bristol-Myers Squibb, Janssen, and Otsuka. He served on a Data Safety Monitoring Board for Boehringer-Ingelheim, Lundbeck, Rovi, Supernus, and Teva. He received royalties from UpToDate and grant support from Janssen and Takeda. He is also a stock option holder of LB Pharma. Dr. Kessing has been a consultant to or has received honoraria or grants from Lundbeck. Dr. Arango has been a consultant to or has received honoraria or grants from Acadia, Angelini, Gedeon Richter, Janssen Cilag, Lundbeck, Otsuka, Roche, Sage, Servier, Shire, Schering Plough, Sumitomo Dainippon Pharma, Sunovion and Takeda. Dr. Bechdolf has been a consultant and/or advisor to or has received honoraria or grants from: Janssen/J&J, LB Pharma, Lundbeck, Otsuka, Pfizer and Recordati. Dr Catalan has received personal fees from Janssen. Dr. Vieta has received grants and served as consultant, advisor or CME speaker for the following entities: Abbott, Allergan, Angelini, Dainippon Sumitomo Pharma, Janssen, Lundbeck, Novartis, Otsuka, Richter, Sage, Sanofi-Aventis, and Takeda. Dr Fusar-Poli has received grants from Lundbeck and personal fees from Menarini, Lundbeck and Angelini. No other disclosures were reported.es_ES
dc.language.isoenges_ES
dc.publisherElsevieres_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/*
dc.subjectpromotiones_ES
dc.subjectgood mental healthes_ES
dc.subjectuniversales_ES
dc.subjectselectivees_ES
dc.subjectinterventiones_ES
dc.subjectoutcomeses_ES
dc.titleUniversal and selective interventions to promote good mental health in young people: Systematic review and meta-analysises_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.holderThis is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)es_ES
dc.rights.holderAtribución-NoComercial-SinDerivadas 3.0 España*
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/pii/S0924977X20309159?via%3Dihubes_ES
dc.identifier.doi10.1016/j.euroneuro.2020.10.007
dc.departamentoesNeurocienciases_ES
dc.departamentoeuNeurozientziakes_ES


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This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
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